2015 American Transplant Congress

May 2-6, 2015 in Philadelphia, Pennsylvania

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Safer and More Effective Treatment of Acute Postoperative Pain in Living Liver Donors

D. Ladner,¹ R. Fisher,² J. Guarrera,³ E. Pomfret,⁴ M. Simpson,⁴ A. Daud,⁵ T. Curtis,⁵ E. Reyes,⁵ A. Skaro,¹ D. Woods.⁵
Safety and Efficacy of 3-Month Ciprofloxacin for BK Prophylaxis in Kidney Transplantation

S. Patel, R. Knight, J. Loucks, S. Kuten, A. Gaber.
Safety and Efficacy of All Oral DAA Therapy for Genotype 1 HCV Post-Liver Transplant: Interval Results from the HCV-TARGET Multicenter Prospective Observational Study

J. O'Leary,¹ R. Brown,² K. Reddy,³ A. Kuo,⁴ G. Morelli,⁵ R. Stravitz,⁶ G. Everson,⁷ C. Durand,⁸ H. Vargas,⁹ P. Kwo,¹⁰ C. Frenette,¹¹ J. Peter,¹² M. Vainorius,¹² L. Akushevich,¹² D. Nelson,⁵ M. Fried,¹² N. Terrault.¹³
Safety and Efficacy of Conversion from Conventional Twice Daily Tacrolimus to Once Daily Extended Release Tacrolimus in Stable Pancreas Transplant (SPK and PAK) Recipients

M. Dib, A. Barbas, M. Marquez, J. Laurence, G. Sapisochin, A. Norgate, J. Schiff, I. McGilvray, P. Greig, M. Selzner, M. Cattral.
Safety and Efficacy of Early Everolimus in De Novo Orthotopic Liver Transplantation

M. Gastaca,¹ I. Bilbao,² M. Jimenez,³ J. Bustamente,¹ C. Dopazo,² R. Gonzalez,³ R. Charco,² J. Santoyo,⁴ J. Ortiz de Urbina.¹
Safety and Efficacy of Low Dose and Very Low Dose Extended-Release Tacrolimus / MMF in De Novo Kidney Transplant Recipients

Y. Watarai,¹ M. Okada,¹ K. Futamura,¹ K. Ito,¹ T. Yamamoto,¹ M. Tsujita,¹ T. Hiramitsu,¹ N. Goto,¹ S. Narumi,¹ T. Kobayashi.²
Safety and Efficacy of Pegylated Interferon and Ribavirin for Chronic Hepatitis C Following Renal Transplantation

G. Chen, L. Zhu, S. Chen, X. Wang, Z. Lin.
Safety and Outcome of Ganciclovir-Resistant CMV Treated With Foscarnet: A Single Center Retrospective Study

B. Pierce,⁴ C. Richardson,⁴ K. Cunningham,⁴ C. D'Agostino,⁴ C. Tseng,⁴ J. Brown,⁴ C. O'Brien,⁴ B. Ho,^1,3,5 M. Ison.^1,2,3
Sarcopenia and Non-Ischemic Cardiomyopathy After Liver Transplantation

A. Mathew,¹ J. Pan,¹ F. Guglielmo,² A. Shah,³ C. Doria,³ D. Sass,¹ D. Halegoua-De Marzio.¹
SBRT(Stereotactic Body Radiotherapy) to Bridge or Down-Size HCC for Liver Transplantation

N. Thai,¹ K. Tom,¹ M. Szramowski,¹ P. Abrams,¹ J. Oliva,³ D. Monga,⁴ M. Raj,⁴ D. Parda,² A. Kirichenko.²
Screening for West Nile Virus in California: Resolving IgM Anti-WNV in the Area With Dengue Seroprevalence

C. Chinchilla-Reyes,^1,2 D. Tanglao,¹ T. Mone,³ M. Koss,¹ M. Nowicki.^1,2
Screening Recipients of Increased Risk Donor Organs: A Multicenter Study

N. Theodoropoulos,¹ K. Brizendine,² M. Ison.³
Selective Blockade of the CD28/B7/CTLA4 Pathway With Monovalent Anti-CD28 Antibodies Versus Targeting of B7 With CTLA4-Ig, in Non-Human Primate Kidney Allograft

S. Ville,¹ N. Poirier,^1,2 B. Vanhove,^1,2 G. Blancho.¹
Selective CD28 Blockade With or Without CD40-CD154 Blockade Promotes Cardiac Allograft Protection in Non-Human Primates

T. Zhang,¹ A. Kronfli,¹ B. Gheorghe,¹ L. Burdorf,¹ E. Rybak,¹ D. Parsell,¹ D. Harris,¹ E. Sievert,¹ S. Dahi,¹ N. Kubicki,¹ J. Whoddal,¹ M. Uluer,¹ X. Cheng,¹ E. Schwartz,¹ K. Quinn,¹ B. Vanhove,² A. Azimzadeh,¹ R. Pierson III.¹
Sensitization Level at Retransplant Among Non-Sensitized Pediatric Recipients of First Deceased Donor Kidney Transplants Not Affected by DR Mismatch Level

W. Cherikh,¹ A. Wilk,¹ H. McGehee,¹ E. Brewer.²
Sequential Monitoring and Stability of Ex Vivo-Expanded Autologous and Non-Autologous Regulatory T Cells Following Infusion in Non-Human Primates

H. Zhang,¹ H. Guo,¹ L. Lu,¹ A. Zahorchak,¹ R. Wiswman,² G. Raimondi,¹ D. Cooper,¹ M. Ezzelarab,¹ A. Thomson.¹
Serial Changes in Body Composition After Kidney Transplantation

S. Deger,¹ A. Bian,² G. Chen,² T. Ikizler,¹ K. Birdwell.¹
Serum Creatinine Is Most Predictive of Graft Loss in Late Antibody Mediated Rejection

G. Agarwal, D. Diskin, R. Reed, J. Locke, V. Kumar.
Serum Osteoprotegerin Levels Positively Correlate With Peripheral Arterial Stiffness in Kidney Transplantation Patients

M.-C. Lee,^1,2 G.-J. Ho,¹ Y.-C. Chen,¹ B.-G. Hsu.²
Serum Phosphorus Level Has Bidirectional Association With Graft Failure and Mortality in Kidney Transplant Recipients

H. Jeon,¹ J. An,² K. Joo,¹ C. Lim,² Y. Oh,² C. Ahn,¹ S.-K. Park,³ Y. Kim,¹ Y. Kim,⁴ J. Lee.²
Serum Proteins Are Significantly Upregulated in Patients With Clinical Antibody-Mediated Rejection

A. Gareau,¹ I. Gibson,² C. Wiebe,¹ J. Ho,¹ D. Rush,¹ P. Nickerson.¹
Serum Uric Acid Is Associated With Hypertension in Kidney Donors

S. Reule,¹ R. Foley,¹ A. Matas,² H. Ibrahim.¹
Severe Refractory Skin Eruption Treated With Plasmapheresis in a Multivisceral Transplant Patient

J. Garcia,¹ T. Beduschi,¹ A. Tekin,¹ J. Fan,¹ S. Nishida,¹ G. Selvaggi,¹ G. Ciancio,¹ G. Burke,¹ C. Katsoufis,² L. Pizano,³ R. Vianna.¹
Severe Sarcopenia and Increased Fat Stores in Pediatric Patients With Liver, Kidney and Intestine Failure

W. Bush, C. Miller, C. Kubal, J. Fridell, A. Tector, R. Mangus.
Sevoflurane Based Anesthesia in Recipients Reduces 2 Year Acute Rejection in Living Donor Kidney Transplantation. Results from the VAPOR-Trial

G. Nieuwenhuijs-Moeke,¹ V. Nieuwenhuijs,² M. Seelen,³ R. Ploeg,² H. Leuvenink,² M. Struys.¹
Sex Differences in Mortality Rate Among Patients Waiting for Liver Transplantation

Z. Cui,^1,2 X. Luo,² A. Massie,² D. Segev.²
Sharp Declines in Access to Live Donor Kidney Transplantation

A. Massie, I. Olorundare, D. Segev.
Short- and Long-Term Outcomes of Mycophenolate Versus Azathioprine in a Large Cohort of Renal Transplant Recipients

L. Bowman,¹ T. Horwedel,¹ J. Hagopian,¹ D. Brennan.²
Short-Term QOL After Live Liver Donation: A New York Center for Liver Transplantation (NYCLT) Report

D. LaPointe Rudow,¹ S. DeLair,² S. Florman,¹ J. Guarrera,³ M. Kinkhabwala,⁴ M. Orloff,⁵ Y. Wu,⁶ L. Teperman.⁷
Should Current IVIg Preparations Containing High Titers of Anti-HLA-I/-II IgG be Used for Lowering the Anti-HLA IgG in Sensitized Pre-Transplant Patients and Allograft Recipients?

M. Ravindranath, P. Terasaki, C. Maehara, V. Jucaud.
Should Only Active Candidates Define the EPTS Top 20% in the New Kidney Allocation System (KAS)?

D. Stewart,¹ A. Kucheryavaya,¹ G. Boyle,¹ M. Aeder,² R. Formica.³
Should We Ever Pay Living Kidney Donors? Focus Group Study of Public Opinion

A. Tong,^1,2 A. Ralph,^1,2 J. Chapman,³ G. Wong,^1,2,3 J. Gill,⁴ M. Josephson,⁵ C. Hanson,^1,2 J. Craig.^1,2
Significance of an Isolated Elevated PRA in Renal Transplantation

S. Kuten, S. Patel, G. Land, T. Eagar, R. Knight, J. Loucks, L. Gaber, A. Gaber.
Significant Association Between Foxp3 Gene Polymorphism and Outcomes in HBV-Related Liver Transplant Patients

Y. Tanaka, V. Sapana, H. Ohdan.
Significant Reduction in TRAIL-Expressing NK Cells in Remnant Liver After Partial Hepatectomy Is Strongly Associated With the Impaired Intrahepatic CXCL9–CXCR3 Pathway

T. Yano, M. Ohira, H. Ohdan.
Similar Outcomes Can Be Expected Among HIV (+) Kidney Transplant Recipients (HIV+ Tx) Vs. HIV (-) Kidney Transplant Recipients (HIV- Tx) Receiving Similar Immunosuppression Protocols

L. Panarey,¹ G. Malat,^2,3 A. Sharma,¹ K. Ranganna,¹ D. Reich,² G. Xiao,² A. Doyle.¹
Simultaneous Cadaveric Pancreas, Living-Donor Kidney Transplantation: Single Center Experience

Y. Kim, J. Jung, H. Cho, J. Hong, J. Choi, B. Choi, S. Shin, D. Han.
Single Cell Phospho-Protein Analysis Demonstrates That Immunosuppressive Drugs Inhibit MAPK and mTOR Signaling Molecules in Primary Monocytes After Transplantation

N. Kannegieter, D. Hesselink, R. Kraaijeveld, G. de Graav, M. Betjes, W. Weimar, C. Baan.
Single Center Experience of C4d Staining of Kidney Transplant Biopsies

R. Prashar, L. Yessayan, M. Goggins, V. Karthikeyan, K. Venkat, A. Patel.
Single Center Experience With the Use of an Abbreviated Anti-Thymocyte Globulin and Basiliximab Combination Protocol in Renal Transplantation

V. Whittaker,¹ D. Halleran,¹ S. Narsipar,¹ J. Melancon.²
Single Infusion of Donor-Type Splenocytes Treated With Extracorporeal Photopheresis Prior to Transplantation Significantly Prolongs Cardiac Allograft Survival in Mice

J. Schneiderman,¹ J. Ye,² X. Yeap,² M. Caralt,² J.-J. Wang,² Z. Zhang.²
Single Nucleotide Polymorphisms (SNPs) Associated With Acute Rejection in European American Kidney Transplant Recipients: A Genome Wide Association Study (GWAS)

A. Israni,¹ C. Dorr,¹ M. Miller,² D. Schladt,¹ K. Sanghavi,³ A. Muthusamy,¹ R. Remmel,³ W. Guan,⁴ B. Wu,⁴ W. Oetting,³ P. Jacobson,³ A. Matas,⁵ For DeKAF Genomics & GEN03 Investigators.¹
Single-Center Analysis of Adult, Combined Heart-Liver Transplant (CHLT) Recipients

H. Monsour Jr,¹ M. Boktour,² A. Abimbola,¹ M. Elnemr,¹ S. Gordon Burroughs,² D. Victor III,¹ A. Saharia,² B. Trachtenberg,³ A. Bhimaraj,³ A. Gaber,² J. Estep,³ R. Ghobrial.²
Sirolimus Based Maintenance Immunosuppression in Pancreas Transplant Recipients

A. Rajab, R. Pelletier, E. Elkhammas, G. Bumgardner, A. El-Hinnawi, M. Henry.
Six Year Follow-Up of a Phase 2 Clinical Trial to Induce Tolerance in Mismatched Living Donor Renal Transplant Recipients

J. Leventhal, M. Abecassis, L. Gallon, J. Galvin, J. Mehta, K. Ravindra, D. Tollerud, M. Elliott, S. Ildstad.
Six-Month Urinary CCL2 Levels Predict Long-Term Renal Allograft Outcome

J. Ho,¹ D. Rush,¹ A. Gao,¹ H. Hopfer,² C. Wiebe,¹ P. Nickerson,¹ S. Schaub,² P. Hirt-Minkowski.²
Small RNA Sequencing-Enabled Discovery of Circulating Extracellular MicroRNAs as Noninvasive Biomarkers of Liver Allograft Status

H. Yang,¹ T. Muthukumar,¹ K. Akat,² D. Briskin,² T. Tuschl,² M. Suthanthiran.¹
Social Support After Heart Transplant

E. Stimpson, T. Kao, L. Kim, S. Morrison, J. Patel, M. Kittleson, F. Liou, S. Siddiqui, J. Yabuno, L. Czer, J. Kobashigawa.
Socioeconomic Determinants of Racial Disparities in Access to Preemptive Live Donor Kidney Transplantation

T. Purnell, X. Luo, A. Massie, D. Crews, L. Cooper, D. Segev.
Socioeconomic Factors and Early Hospital Readmission After Kidney Transplant at a Single Center

J. Lin, E. King, R. Craig-Shapiro, C. Wickliffe, A. Massie, D. Segev.
Socioeconomic Predictors of Organ Donation in Pediatric Donors

M. Shah, V. Vilchez, A. Goble, E. Maynard, R. Gedaly.
Socioeconomic Status of Local Vs Exported Liver Recipients and Their Donors

J. Adler,¹ J. Hyder,² J. Markmann,¹ H. Yeh.¹
Sofosbuvir Therapy in Early and Late Post Liver Transplant Setting: A Single Center Experience

X. Zervos,¹ D. Beltran,² B. Ismail,¹ M. Watson,¹ D. Sears,¹ A. Tzakis.¹
Sofosbuvir-Based Therapy for Hepatitis C Recurrence Post Liver Transplantation

A. Ajlan,¹ A. Aljedai,¹ H. Elsiesy,² D. Alkortas,¹ R. Alarieh,² F. Aba Alkhail.²
Somatostatin (Eumedica®) Infusion Allows Modulating Graft Flows and Gradients in Liver Transplantation. Results of a Randomized, Double Blind, Placebo Controlled Trial

R. Troisi,¹ A. Croo,¹ E. Codarin,³ E. De Wolf,¹ J. Van Limmen,⁴ G. Antoniali,³ B. Heyse,⁴ L. De Baerdemaeker,⁴ I. Colle,⁵ G. Tell,³ M. Sainz-Barriga.^1,2
South Asians Have a Higher Risk of PTDM and Death After Renal Transplantation

D.-A. Moutzouris, L. Kozia, M. Willicombe, R. Corbett, N. Duncan, J. Galliford, A. McLean, D. Taube.
Speed of Onset of Donor Brain Death Leads to Differences in Renal Function and Expression of Inflammatory and Oxidative Stress Markers in Rat Kidneys

D. Hoeksma,¹ R. Rebolledo,² M. Hottenrott,³ Y. Bodar,¹ H. Leuvenink.¹
Spironolactone Prevents Calcineurin Inhibitors Toxicity in Renal Allografts. Preliminary Report

J. Martinez, I. Vargas, B. Chagolla, A. Ramirez, J. Bermudez.
Split and Living Donor Versus Whole Liver Transplantation for Hepatocellular Carcinoma in Adult Recipients: A Single Center Analysis

O. Boillot, O. Guillaud, J. Dumortier.
Stability of Kidney Allograft Function Is Improving Over Time Across All Donor Types

J. Gill, J. Dong, C. Rose, J. Gill.
Stable and Unstable Chimerism During Immunosuppressive Drug Withdrawal in Tolerant Recipients of HLA Matched Combined Kidney and Hematopoietic Cell Transplants

T. Pham,¹ S. Busque,¹ J. Scandling,² J. Shizuru,² S. Asha,¹ S. Strober.²
Standardizing Quality Improvement Practices in Pediatric Liver Transplantation: The SPLIT A3 Project

B. Kelly,¹ R. Himes,² J. Bucuvalas,³ L. Ware,¹ S. Horslen.⁴
Stem Cell and Novel Biologic Therapies to Enhance Functional Recovery in Limb Transplantation

K. Kniery, M. DeHart, T. Brown, S. Salgar.
Steroid Free Immunosuppression Protocol in Pediatric Kidney Transplant Recipients Using Alemtuzumab: A Retrospective Single Center Study

R. Shah,¹ Z. Kadry,¹ S. Wassner,² D. Kees-Folts,² M. Freeman,² P. Freeman,¹ B. Olenowski,¹ A. Jain.¹
Steroid-Free Quadruple Induction Regimen With Basiliximab, Everolimus, Mycophenolate and Very Low Dose Tacrolimus Reduces Incidence of Biopsy-Proven Acute Rejection and Toxicity Profile Compared to the Standard Triple Regimen

M. Miura, H. Higashiyama.
Stimulating Protease Inhibitor 9 Expression By Human Regulatory T Cells Improve Homeostasis

P. Lukyanchykov, Z. Solhjou, A. Radwan, L. Riella, A. Chandraker, R. Abdi, J. Azzi.
Structural and Functional Basis for Non-HLA Antibody Mediated AT1R Activation

D. Dragun, D. Postpieszala, N. Zhu, R. Catar, A. Philippe.
Structure/Function Insights Into Treg Biology: Hdac11 Is a Foxp3 Deacetylase Whose Targeting Promotes and Stabilizes Foxp3 Expression and Leads to Long-Term Allograft Survival

J. Huang,¹ L. Wang,¹ T. Bhatti,¹ A. Samanta,¹ S. Dahiya,¹ R. Han,¹ J. Bergman,² A. Kozikowski,² W. Hancock.¹
Suboptimal Vaccination Coverage After Liver Transplantation: Opportunity for Improvement

L. Danziger-Isakov, S. Blum, G. Paulsen, M. Lake, R. Rengering, M. Duncan, J. Zigmond, K. Campbell, J. Bucuvalas.
Successful Consolidation of Two Kidney/Pancreas Transplant Programs

D. Morgan, A. Tietjen, S. Mulgoankar.
Successful Management of Post Transplant Focal Segmental Glomerulosclerosis With Plasma Exchange and Rituximab

K. Koutroutsos,¹ R. Charif,¹ C. Roufosse,² J. Galliford,¹ D. Taube,¹ M. Loucaidou.¹
Superior Outcomes of Kidney Transplantation Compared With Dialysis in Korea: A Propensity–Matched Analysis of a National Population-Based Cohort Study Between 2005 and 2008

K. Yoo,¹ C. Kim,² J. Lee,³ M.-H. Kim,⁴ H. Cho,¹ K. Kim,⁵ H. Kim,⁶ D.-R. Ryu,⁷ D. Kim,¹ C. Lim,⁸ Y. Kim,¹ J. Lee.⁸
Superior Renal Function in an Everolimus-Based Calcineurin Inhibitor Free Regimen Compared to Standard Cyclosporine/Mycophenolate and Low Cyclosporine/Everolimus: Follow-Up of the HERAKLES Study at Month 48

K. Budde,¹ C. Sommerer,¹ P. Weithofer,¹ O. Witzke,¹ M. Guba,¹ J. Jacobi,¹ B. Vogt,³ I. Hauser,¹ R. Stahl,¹ P. Reinke,¹ T. Rath,¹ D. Baeumer,² M. Porstner,² M. Zeier,¹ F. Lehner,¹ W. Arns.¹
Surgical Error: A Common, Preventable Threat to Deceased Donor Organs

A. Friedman,¹ T. Diflo,² S. Florman,³ L. Ratner,⁴ E. Marquez,¹ W. Tajik.¹
Surgical Site Infections After Intestinal and Multivisceral Transplantation

K. Etesami, R. Girlanda, J. Steele, Y. Kwon, J. Hawksworth, C. Desai, E. Island, C. Matsumoto, T. Fishbein.
Survival Benefit of ECD Transplantation After Ultra-Long Dialysis Exposure: Implications for Acceptance in the New KAS

C. Kennedy, J. Dong, T. Myint, C. Rose, O. Johnston, J. Gill, J. Gill.
Survival Benefit of Kidney Transplant Among HIV+ Waitlist Candidates

J. Locke,¹ S. Gustafson,² C. Durand,³ J. Snyder,² B. Shelton,¹ R. Reed,¹ P. MacLennan,¹ S. Mehta,¹ A. Nellore,¹ D. Segev.^2,3
Survival Benefit of Kidney Transplantation With Expanded Criteria Kidney from Donors After Circulatory Death

X. Luo, A. Massie, E. Chow, D. Segev.
Survival Benefit of Liver Transplant Among HIV+ Waitlist Candidates

C. Durand,¹ S. Gustafson,² J. Locke,³ J. Snyder,² B. Shelton,³ R. Reed,³ P. MacLennan,³ S. Mehta,³ A. Nellore,³ D. Segev.^1,2
Survival Benefit of Simultaneous Liver Kidney (SLK) Transplant in Liver Transplant Candidates With Renal Dysfunction

B. Tanriover,¹ S. Zhang,² J. Marrero.³
Survival of Patients With Peripheral Vascular Disease on Kidney Waitlist and After Transplantation: An Analysis of the United State Renal Data System

A. Brar,¹ D. Stefanov,³ R. Jindal,² N. Sumrani,⁴ D. John,⁴ F. Tedla,¹ M. Salifu.¹
Survival Outcomes of Kidney Transplant Recipients from Expanded Criteria Donors: A Systematic Review and Meta-Analysis

A.-H. Querard,^1,2,3 F. Gillaizeau,^1,3 Y. Foucher,^1,3 E. Dantan,³ D. Larmet,¹ M. Lorent,³ L.-M. Pouteau,¹ C. Combescure,⁴ M. Giral.^1,3,5
Switching from Tacrolimus to Low-Dose Cyclosporine A Preserves Allograft Function in Presumptive and Definitive Polyomavirus-Associated Nephropathy

G. Huang, C.-X. Wang, J.-G. Fei, J. Qiu, S.-X. Deng, J. Li, G.-D. Chen, Q. Fu, R.-H. Deng, L.-Z. Chen.
Systematic Medical Record Review to Identify Safety Risks in Living Liver Donors

B. Platt,⁵ D. Woods,⁵ R. Fisher,² J. Guarrera,³ E. Pomfret,⁴ M. Simpson,⁴ A. Daud,¹ T. Curtis,⁵ E. Reyes,⁵ E. Wymore,⁵ A. Skaro,¹ D. Ladner.¹
Systemic and Local NK and Regulatory Cell Phenotypes and mTori-Induced Tumor-Specific Effector T-Cell Responses Are Key Players Favoring the Development of Squamous Cell Skin Carcinoma Among Kidney Transplant Patients

E. Crespo,¹ M. Lucia,¹ L. Fernandez,³ E. Melilli,² S. Luque,¹ R. Lauzurica,³ J. Cruzado,^1,2 J. Torras,^1,2 J. Grinyó,^1,2 O. Bestard.^1,2

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