2016 American Transplant Congress
Th17 Development Is Critical for Airway Epithelial Injury After Transplantation.
Department of Immunology, Capital Medical University, Beijing, China.
Background: Development of obliterative bronchiolitis (OB) is the biggest obstacle that limits long-term allograft survival and clinical application of lung transplantation, and the precise mechanisms…2016 American Transplant Congress
Activation of Innate Immunity During Human OLT-IRI Triggers Adaptive Immunity and Correlates with the Degree of IRI Injury.
1Surgery, Dumont-UCLA Transplant Ctr, Los Angeles, CA; 2Pathology, UCLA, Los Angeles, CA.
Ischemia reperfusion injury (IRI) in orthotopic liver transplantation (OLT) can severely compromise graft and recipient survival. We postulate this is mediated by interactions between the…2016 American Transplant Congress
Morbidity and Mortality of Early Post-Operative Acute Kidney Injury in Cardiothoracic Transplant Recipients.
Tampa General Hospital, Tampa, FL.
Purpose: Early acute kidney injury (AKI) in cardiothoracic transplant recipients (CTTR) has not been well described; renal injury defined by the RIFLE criteria has been…2016 American Transplant Congress
Clinical Predictors of Progression and Clearance of Low Level CMV Viremia in Solid Organ Transplant Recipients.
Multi-Organ Transplant Program, University Health Network, Toronto, ON, Canada.
Background: Low level CMV viremia is common, and may either progress to higher viral loads that require therapy, or may spontaneously resolve. The clinical predictors…2016 American Transplant Congress
Characterization of Resistant Cytomegalovirus in Lung Transplant Recipients in the Modern Era.
NewYork-Presbyterian Hospital, New York, NY.
Cytomegalovirus (CMV) remains a major cause of morbidity and mortality in lung transplant recipients (LTR) and the emergence of resistant CMV (rCMV) has increased. The…2016 American Transplant Congress
Hepatitis B Reactivation Among Non-Liver Solid Organ Transplant Recipients.
IntroductionThe purpose of this study was to evaluate the incidence of post-transplant hepatitis B (HBV) reactivation in patients who have previously cleared hepatitis B surface…2016 American Transplant Congress
An Analysis of Non-Tuberculous Mycobacteria (NTM) Infection and Colonization in Lung Transplant Recipients (LTRs) Post-Transplant: A Single Center Matched Cohort Study.
PurposeNTM is a common infection after Lung transplantation. The role of presence of granuloma in the explanted lungs of LTRs in subsequent development of infection…2016 American Transplant Congress
MiRNA-200b Inhibits Epithelial-Mesenchymal Transition in TGF-β1 Induced Human Bronchial Epithelial Cells.
Institute of Cellular Medicine, Newcastle University, Newcastle Upon Tyne, United Kingdom.
The role of TGF-β1 in mediating extracellular matrix remodeling during the pathogenesis of lung fibrosis has been well defined. Dysregulated expression of miRNA is increasingly…2016 American Transplant Congress
Susceptibility Patterns of Pre-Transplant Pseudomonas and Post-Lung Transplant Outcomes in Patients with Cystic Fibrosis.
Background: The impact of pre-lung transplant (LT) pan-drug-resistant Pseudomonas aeruginosa (PDR PsA) colonization on post-LT mortality and bronchiolitis obliterans syndrome (BOS) rates in cystic fibrosis…2016 American Transplant Congress
The Apoptosis of the Tracheal Epithelia Increase the Recipient's MSCs Derived Myofibroblasts in Allografts to Exacerbate Obliterative Bronchiolitis After Tracheal Transplantation in Mice.
Background: The long-term outcome of lung transplantation is impeded by obliterative bronchiolitis (OB). However, the current treatment cannot effectively prevent the process of OB. The…
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