2019 American Transplant Congress
Circulating Exosomes Isolated from Human Lung Transplant Recipients with Respiratory Viral Infections Contain Nucleic Acids Specific to Virus and Can Lead to Activation of Stress Proteins
Norton Thoracic Institute, St. Joseph’s Hospital and Medical Center, Phoenix, AZ
*Purpose: Exosomes are membrane vesicles released by cells into body fluids. Our laboratory demonstrated the presence of circulating exosomes with lung self-antigens (SAgs), Collagen V…2019 American Transplant Congress
A Randomized Pilot Trial of Home-Based Physical Activity Plus Dietary Intervention to Improve Physical Function in Patients with Advanced Liver Disease
*Purpose: Deconditioning and frailty are prevalent among liver transplant (LTx) candidates and prehabilitation programs have been proposed in order to improve clinical outcomes. However, few…2019 American Transplant Congress
The Molecular Features of Chronic Lung Allograft Dysfunction (CLAD) in Transbronchial and Endobronchial Mucosa Biopsies
1University of Alberta, Edmonton, AB, Canada, 2ATAGC, University of Alberta, Edmonton, AB, Canada
*Purpose: Chronic lung allograft dysfunction (CLAD), the major long-term problem in lung transplantation, requires new strategies for prevention and management. However, CLAD is infrequently diagnosed…2019 American Transplant Congress
Caregiving in Thoracic Transplantation–A SR/MA
*Purpose: Caregivers are required for heart and lung transplantation, however, little emphasis is placed on the pre-transplant caregiving experience. Our objective was to perform a…2019 American Transplant Congress
Bronchoalveolar Lavage Biomarkers Predict Lung Transplant Survival
*Purpose: In lung transplants (LTx), chronic rejection remains a major cause of morbidity and mortality following transplantation, mainly from chronic lung allograft dysfunction (CLAD). Two…2019 American Transplant Congress
Syphilis Transmission in Solid Organ Transplantation
Emory University Hospital, Atlanta, GA
*Purpose: Syphilis is a sexually transmitted infection that affects people worldwide. While transmission generally occurs via sexual contact, other modes of transmission are possible, including…2019 American Transplant Congress
Azole Use and Fungal Pathogens in Cystic Fibrosis versus Non-Cystic Fibrosis Lung Transplant Recipients
*Purpose: Cystic fibrosis (CF) patients exhibit unique pharmacokinetic principles. Azole antifungals show marked inter- and intra-patient variability. We aimed to improve itraconazole (ITR) use and…2019 American Transplant Congress
Not All Donor-Specific Antibodies Are Equal: Predictors of Risk of Chronic Lung Allograft Dysfunction
*Purpose: Donor-specific HLA antibodies (DSA) have been previously associated with chronic lung allograft dysfunction (CLAD). However, the DSA characteristics that predict risk of CLAD are…2019 American Transplant Congress
Impact of Multidrug-Resistant Microbes of Donor Lower Respiratory Tract on Early Posttransplant Pneumonia in Bilateral Lung Transplant Recipients without Pretransplant Infection
*Purpose: Colonized microbes in lower respiratory tract (LRT) of deceased donor allograft can potentially cause early posttransplant pneumonia (EPTP) that leads to detrimental outcome in…2019 American Transplant Congress
Effect of Enoxaparin Prophylaxis on Early VTE Post Lung Transplant
*Purpose: Thromboembolic complications are common post-transplant leading to significant morbidity. We instituted early enoxaparin prophylaxis (ppx) in lung transplant recipients (LTR) due to an observed…
American Transplant Congress abstracts