2018 American Transplant Congress
Characterization of Exosomal DNA from Human Lung Transplant Recipients
Norton Thoracic Institute, St. Joseph's Hosp & Med Ctr, Phoenix.
Exosomes are small vesicles which contains biological molecules including proteins, RNA`s and miRNAs. It has been reported that exosomes may contain ds DNA originated from…2018 American Transplant Congress
Pattern of Respiratory Virus Infection (RVI) and Chronic Lung Allograft Dysfunction (CLAD) in Lung Transplant Recipients (LTR)
University of ALberta, Edmonton, AB, Canada.
Background: The indirect effects of RVI in LTR are controversial. We aimed to define patterns of RVI in LTR and the impact on CLAD and…2018 American Transplant Congress
Simultaneous Persistence and Development of Donor and Recipient Tissue Resident Memory T Cells in Lung Transplantation
Introduction: The predominant T cell population in the lung comprises non-circulating tissue-resident memory T cells (TRM); however, the fate of these cells in transplanted lung…2018 American Transplant Congress
Superiority of Early Everolimus-Based Quadruple Immunosuppression versus Standard Triple Therapy after Lung Transplantation: 12 Months Results from Prospective 4EVERLUNG Study in Germany
The 4Everlung trial was designed to evaluate the benefit of early everolimus (EVR)-based quadruple low immunosuppressive (IS) regimen on kidney function (RF) after LTx.4EVERLUNG is…2018 American Transplant Congress
Identification of Exosomal Proteins from Human Lung Transplant Recipients
Molecular mechanisms involved in rejection following human lung transplantation are not well understood. Goal of this study is to identify proteomic signatures in the circulating…2018 American Transplant Congress
Ultrastructural Changes in Lung Allografts: Endothelial Changes Correlate with Donor Specific Antibody & Antibody Mediated Rejection
Introduction: Antibody mediated rejection (AMR) causes lung allograft (LA) injury. Challenges with C4d interpretation & lack of specific histological criteria account for difficulty in diagnosing…2018 American Transplant Congress
Nontuberculous Mycobacteria in Lung Transplant Recipients: Prevalence, Risk Factors and Impact on Survival and Graft Function
University of Alberta, Edmonton, Canada.
BACKGROUND. Nontuberculous mycobacteria (NTM) may colonize or infect lung transplant patients. Due to differences in populations studied and geographical diversity of NTM, risk factors for…2018 American Transplant Congress
Impact of Changes to the LAS Calculation
Purpose: On 2/19/2015 major revisions to the Lung Allocation Score (LAS) calculation were made to more appropriately reflect candidates' waiting list urgency and post-transplant survival.…2018 American Transplant Congress
Long-Term HIF-1α Stabilization is Associated with Fibrosis in Rat Lung Allografts
Introduction: HIF-1α is a subunit of a heterodimeric transcription factor hypoxia-inducible factor 1 (HIF-1) and functions as a master transcriptional regulator of cellular and developmental…2018 American Transplant Congress
Evaluation of Immunosuppression and Infection after Desensitization in Lung Transplantation
University of Maryland Medical Center, Baltimore.
Purpose: To reduce waitlist time for sensitized lung transplant recipients (LTR), our center used peri-operative desensitization for LTR with a positive virtual crossmatch (P-VXM). We…
American Transplant Congress abstracts