2020 American Transplant Congress
Temporal Trends in Utilization and Outcomes of Sclerotic Donor Kidneys in the United States
Johns Hopkins University, Baltimore, MD
*Purpose: Sclerotic donor kidneys (SDK, glomerulosclerosis ≥20% on biopsy) represent a possible expansion to the donor pool but are often discarded due to historical association…2020 American Transplant Congress
Hif-1a Expression Influences Recipient Clinical Outcomes in Liver Transplant Patients
Liver Transplant Surgery, UCLA, Los Angeles, CA
*Purpose: Liver ischemia-reperfusion injury (IRI), an innate-immune dominated hepatocellular damage, is a risk factor for early allograft dysfunction (EAD) and rejection crises in liver transplantation…2020 American Transplant Congress
Effect of Everolimus and Reduced Calcineurin Inhibitors on Biopsy Proven BK Virus Associated Nephropathy
Cleveland Clinic, Cleveland, OH
*Purpose: BK virus-associated nephropathy (BKVAN) is a clinically important entity that contributes to allograft loss in kidney transplant recipients (KTRs). Mammalian target of rapamycin inhibitors…2020 American Transplant Congress
Ikaros Regulates Macrophage Inflammation in Liver Ischemia-Reperfusion Injury: From Mouse-to-Human
1Liver Transplant Surgery, UCLA, Los Angeles, CA, 2NIEHS, Durham, NC
*Purpose: Hepatic ischemia-reperfusion injury (IRI) represents a major risk factor for early allograft dysfunction and rejection episodes in liver transplantation (LT). The impact of Ikaros,…2020 American Transplant Congress
Interstitial Inflammation with Chronic Allograft Injury Best Predicts Graft Loss
Einstein-Montefiore Transplant Center, Bronx, NY
*Purpose: We aimed to identify clinical, serological and histopathological predictors of graft loss in kidney transplant recipients who underwent clinically indicated graft biopsies for worsening…2020 American Transplant Congress
Automatic Quantification of Interstitial Fibrosis in Renal Allograft
*Purpose: Renal allografts are typically assessed by pathologists using the Banff classification with known interobserver variability. We previously demonstrated the utility of image analysis in…2020 American Transplant Congress
Five Year Patient Important Outcomes of Treated Acute Rejections Diagnosed with Protocol and Clinical Biopsy after Pancreas Transplant Alone for Type 1 Diabetes
*Purpose: STUDY PURPOSE: Acute rejection (AR) after Pancreas Transplant alone (PTA) continues to be a significant morbidity. We compared the outcomes of PTA recipients treated…2019 American Transplant Congress
The Safety of Surveillance and Indication Biopsies in Kidney Transplantation: A Series of 2000 Biopsies
*Purpose: Kidney biopsy (KB) remains the most important diagnostic tool in kidney transplantation. Despite its value, surveillance KB are not routinely done at majority of…2019 American Transplant Congress
A Potential Role for IgE-Mediated Immune Response in the Pathogenesis of Chronic Antibody-Mediated Rejection
*Purpose: Chronic antibody-mediated rejection (CAMR) is the main cause of graft loss and shares with systemic lupus erythematosus (SLE) the antibody-mediated kidney damage and the…2019 American Transplant Congress
Liquid Biopsy for Chronic Rejection after Kidney Transplantation. A Novel Non-Invasive Biomarker Involved in Inflammatory Amplifier
*Purpose: In kidney transplantation (KTx), despite recent advances of medical technology, chronic rejection accounts for 25% of the graft loss. Chronic active antibody-mediated rejection (CAAMR)…
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