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Articles tagged "Biopsy"

  • 2015 American Transplant Congress

    Treatment of Subclinical Rejection Identified On Surveillance Biopsy May Prevent the Development of Chronic Alloimmune Injury

    M. Willicombe, C. Roufosse, J. Galliford, A. McLean, D. Taube.

    Imperial College Kidney and Transplant Centre, Hammersmith Hospital, London, United Kingdom.

    Surveillance biopsies [SBx] are not universally performed following renal transplantation. In patients in whom protocol biopsies are performed, how best to manage subclinical rejection [SCR]…
  • 2015 American Transplant Congress

    Early Detection of HCC Mutations in Indeterminate Lesions Using Liquid Biopsies

    Y. Lin,1 K. Cavaness,2 Z. Zhang,1 S. Lin,3 K. Korenblat,1 G. Klintmalm,2 W. Chapman.1

    1Washington University, St. Louis, MO; 2Baylor University, Dallas, TX; 3Stanford University, Palo Alto, CA.

    Background Recent sequencing efforts have characterized the mutation profile of hepatocellular carcinoma (HCC); however, the relevance to clinical decision-making has been limited by the infrequency…
  • 2015 American Transplant Congress

    The Impact of Microcirculation Inflammation in Predicting Treatment Response for Late Onset Antibody Mediated Rejection

    J. Lee,1 J. Lee,1 B. Lim,2 B. Kim,3 M. Ju,1 M. Kim,1 S. Kim,1 Y. Kim,1 H. Jeong,2 K. Park,4 K. Huh.1

    1Department of Transplantation Surgery, Yonsei University Health System, Seoul, Republic of Korea; 2Department of Pathology, Yonsei University Health System, Seoul, Republic of Korea; 3Department of Internal Medicine, Yonsei University Health System, Seoul, Republic of Korea; 4Department of Surgery, CHA Bundang Medical Center, Bundang, Republic of Korea.

    BackgroundThere have been marked advances of immunosuppression. However, management of late onset antibody-mediated rejection (AMR) after 6 months is still challenging. Despite important diagnostic and…
  • 2015 American Transplant Congress

    OX40 Gene: A Potential Target for the Care of Chronic T-Cell Mediated Rejection (TCMR)

    F. Schena,1 C. Curci,1 F. Sallustio,1 M. Trpevski,1 G. De Palma,1 M. Fiorentino,2 M. Rossini,2 M. Quaglia,3 E. Bozzola,3 S. Zanini,4 L. Furian,4 A. Toscano,5 E. Gallo,6 L. Gesualdo,2 P. Stratta,3 P. Rigotti,4 F. Citterio,5 L. Biancone.6

    1C.A.R.S.O. Consortium, Valenzano, Italy; 2University of Bari, Bari, Italy; 3A.O.U. Maggiore della Carità, Novara, Italy; 4University of Padova, Padua, Italy; 5Cattolica Sacro Cuore University, Rome, Italy; 6University of Torino, Turine, Italy.

    Introduction:TCMR is characterized by the reduction of vessel lumen with marked intimal thickening, fibrous hyperplasia and a strong component of leukocyte infiltrate. Aim of our…
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