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American Transplant Congress abstracts

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Articles tagged "Methodology"

  • 2018 American Transplant Congress

    Evaluation of FlowDSA Crossmatch for Detection of Donor-Specific HLA Antibodies

    J. Lee, J. Ryu, A. Choi, E-.J. Oh.

    Laboratory Medicine, Seoul St. Mary's Hospital, the Catholic University of Korea, Seoul, Republic of Korea.

    Background: Donor-specific HLA antibodies (DSA) are detected by different crossmatch techniques. Flow cytometric crossmatching (FCXM) is sensitive method, but it is subject to false (+)…
  • 2018 American Transplant Congress

    Immune Phenotyping in a Pediatric Multicenter Transplant Study: Suitability of a Pre-Formulated Dry Antibody Panel System

    S. Urschel,1 L. Ionescu,1 T. Blydt-Hansen,3 B. Foster,5 S. Mital,2 U. Allan,2 S. Iveson,3 L. Hamiwka,4 J. Yap,1 V. Phan,5 P. Birk,6 L. West,1 M. Levings.3

    1U of Alberta, Edmonton, Canada; 2Sickkids, Toronto, Canada; 3U of BC, Vancouver, Canada; 4U of Calgary, Calgary, Canada; 5Montreal Children's, Montreal, Canada; 6U Manitoba, Winnipeg, Canada.

    Background:Flow cytometric immune-phenotyping is influenced by cryopreservation and inter-laboratory variability limiting comparability in multi center studies. The Duraclone™ system (DC) provides optimized pre-mixed dry antibody…
  • 2018 American Transplant Congress

    AT1R Antibody Analysis: High Proportion of Non-Specific Reactivity?

    A. Halpin,1,3,4,5 S. Abou-Zeki,3 I. Larsen,1,4 P. Campbell,2,3,4,5 S. Urschel,1,4,5 L. West.1,3,4,5

    1Dept of Pediatrics, U of Alberta, Edmonton, Canada; 2Dept of Medicine, U of Alberta, Edmonton, Canada; 3Dept of Lab Medicine & Pathology, U of Alberta, Edmonton, Canada; 4ATI, , Canada; 5CNTRP, , Canada.

    INTRODUCTION:The angiotensin II type 1 receptor (AT1R) is expressed on vascular endothelium. AT1R antibodies (Ab) have been studied to examine their relevance in renal and…
  • 2018 American Transplant Congress

    Multidisciplinary Approach to Prevention of Cytomegalovirus (CMV) Complications in Kidney and Liver Transplant Recipients

    S. Shoham,1 S. Anderson,2 R. Avery,1 M. Belden,3 L. Boyer,3 W. Cochran,3 N. Desai,1 M. Holechek,3 E. Kraus,1 J. Langlee,3 P. Spitz,2 K. Marr.1

    1Johns Hopkins University School of Medicine, Baltimore, MD; 2IT@JH Epic, JHMI: Johns Hopkins Health System, Baltimore, MD; 3Comprehensive Transplant Center, JHMI: Johns Hopkins Hospital, Baltimore, MD.

    Background: CMV infection can be prevented in most SOT recipients providing that a prevention protocol is followed. We discovered that our center's protocol, which includes…
  • 2018 American Transplant Congress

    Program-Specific Transplant Rate Ratios: Association with Allocation Priority at Listing and Posttransplant Outcomes

    A. Wey, S. Gustafson, N. Salkowski, J. Pyke, B. Kasiske, A. Israni, J. Snyder.

    SRTR, Mineapolis.

    The Scientific Registry of Transplant Recipients (SRTR) has updated the transplant rate and waitlist mortality risk-adjustment models to include a wider range of candidate characteristics…
  • 2018 American Transplant Congress

    A 5-Tier System for Categorizing Program-Specific Adjusted Transplant and Waitlist Mortality Rate Ratios

    A. Wey, N. Salkowski, B. Kasiski, A. Israni, J. Snyder.

    SRTR, Minneapolis.

    SRTR may begin reporting tiers for program-specific transplant and waitlist mortality rate ratios. A 3-tier system based on statistical hypothesis testing has several deficiencies. Waitlist…
  • 2018 American Transplant Congress

    Informed Clustering of Donor Service Areas for Better Benchmarking

    S. Noreen, R. Carrico, J. Rosendale.

    United Network for Organ Sharing, Richmond, VA.

    The 58 Donor Service Areas (DSA) represent territories of varying geographic sizes, densities and populations. The intention of this project is to group DSA based…
  • 2018 American Transplant Congress

    Prediction of 90 Days Readmission after Kidney Transplantation Including Natural Language Processing

    X. Zhang,1 M. Arenson,4 J. Kim,4 G. Karadkhele,1 J. Hogan,1,5 Y. Zhang,6 A. Adams,1 R. Patzer.1,2,3

    1Department of Surgery, Emory University, Atlanta; 2Department of Epidemiology, Emory University, Atlanta; 3Emory Transplant Center, Emory Healthcare, Atlanta; 4School of Medicine, Emory University, Atlanta; 5Department of Pediatrics, Emory University, Atlanta; 6Rollins School of Public Health, Emory University, Atlanta.

    Early identification of hospital readmission for End Stage Renal Disease (ESRD) patients who obtained kidney transplantation potentially help decrease their risk of readmission after transplantation,…
  • 2018 American Transplant Congress

    Novel Approach to Molecular Testing Using Routine Diagnostic Tissue

    P. Herzyk,1 F. McMonagle,1 P. Shiels,1 S. Coley.2

    1University of Glasgow, Glasgow, United Kingdom; 2Columbia University, New York.

    Currently, molecular diagnostics in kidney transplantation requires dedicated fresh tissue. This requirement limits use in mainstream clinical settings due to perceived increased patient risk in…
  • 2018 American Transplant Congress

    Transplant Psychiatry- A Growing Subspecialty. Introducing the Transplant Psychiatry Special Interest Group from the Academy of Psychosomatic Medicine

    P. Zimbrean,1 A. DiMartini,2 C. Crone.3

    1Psychiatry and Surgery (Transplant), Yale University, New HAven, CT; 2Psychiatry and Transplant, University of Pittsburgh, Pittsburgh, PA; 3Psychiatry, Inova Hospital, Falls Church, VA.

    Purpose: 1. To inform the AST community about the activities of Transplant Psychiatry Special Interest Group that has been operating within the Academy of Psychosomatic…
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