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Articles tagged "Methodology"

  • 2019 American Transplant Congress

    Apparatus and Method to Facilitate In-Situ Cold Perfusion of Abdominal Organs in DCD Donors

    M. Jendrisak

    Gift of Hope Organ & Tissue Donor Network, Itasca, IL

    *Purpose: Rapid, effective in-situ cold perfusion of the abdominal organs in the setting of donation after circulatory death (DCD) is a critical surgical task to…
  • 2019 American Transplant Congress

    Validation Of The Optimized Prediction Of Mortality (Opom) Machine Learning Model For Non-hepatocellular Carcinoma Candidates Awaiting Liver Transplant

    L. Lau1, X. Xie2, F. Jia2, P. D. Greig1, T. C. Chan2

    1Multi-Organ Transplant, Department of Surgery, University of Toronto, Toronto, ON, Canada, 2Mechanical and Industrial Engineering, University of Toronto, Toronto, ON, Canada

    *Purpose: Currently the Model for End-Stage Liver Disease (MELD) is used to rank candidates for liver transplant in many jurisdictions. However, MELD does not provide…
  • 2019 American Transplant Congress

    Creating Geographic Catchment Areas for Solid Organ Transplant Centers

    K. Ross1, R. Patzer2, D. Axelrod3

    1Emory University, Emory Transplant Center, Georgetown, TX, 2Emory University, Emory Transplant Center, Georgetown, GA, 3Dept of Surgery, University of Iowa, Iowa City, IA

    *Purpose: While measurement of transplant center performance has traditionally begun at listing, there is a significant population of potential candidates who may benefit from transplant…
  • 2019 American Transplant Congress

    Using Transplant Referral Regions to Measure Access to Kidney Transplant

    K. Ross1, D. Axelrod2, R. Patzer1

    1Emory University, Emory Transplant Center, Atlanta, GA, 2Dept of Surgery, University of Iowa, Iowa City, IA

    *Purpose: The transplant community has advocated to emphasize pre-transplant quality metrics to promote access to kidney transplantation (KT). Measuring access to transplant requires a well-defined,…
  • 2019 American Transplant Congress

    Tacrolimus Concentrations Can Be Reliably Measured in Capillary Microsamples

    M. T. Gustavsen, N. Vethe, M. Lauritsen, A. Andersen, A. Åsberg, S. Bergan, K. Midtvedt

    Oslo University Hospital, Rikshospitalet, Oslo, Norway

    *Purpose: Routine therapeutic drug monitoring (TDM) of tacrolimus (Tac) is currently performed in venous bloods samples drawn at the hospital. The novel volumetric absorptive microsampling…
  • 2019 American Transplant Congress

    Proteomics Reveals Molecular Window and Metabolism of Normothermically Perfused Human Kidneys

    A. Weissenbacher1, H. Huang2, A. Thorne3, L. M. Lo Faro3, J. Hunter3, R. Ploeg3, C. C. Coussios4, P. J. Friend3, B. Kessler5

    1Visceral, Transplant and Thoracic Surgery, Innsbruck Medical University, Innsbruck, Austria, 2Nuffield Department o Medicine, Target Discovery Institute, University of Oxford, Oxford, United Kingdom, 3Nuffield Department of Surgical Sciences, University of Oxford, Oxford, United Kingdom, 4Oxford Institute of Biomedical Engineering, University of Oxford, Oxford, United Kingdom, 5Nuffield Department o Medicine, Target Discovery Instituteiscovery Institute, University of Oxford, Oxford, United Kingdom

    *Purpose: We have shown that 24h normothermic kidney perfusion (NKP) with urine recirculation (URC) is superior to non URC for maintaining homeostasis previously. However, the…
  • 2019 American Transplant Congress

    Modeling Patients as Dynamical Systems: Evaluating the Efficiency of Kidney Transplantation through Multi-Stage Data Envelopment Analysis

    F. J. Santos Arteaga1, D. Di Caprio2, D. Cucchiari3, J. M. Campistol3, F. Oppenheimer3, F. Diekmann3, I. Revuelta3

    1Faculty of Economics and Management, Free University of Bolzano, Bolzano, Italy, 2Department of Mathematics and Statistics, York University, Toronto, ON, Canada, 3Department of Nephrology and Kidney Transplant, Hospital Clinic, Barcelona, Spain

    *Purpose: The occurrence of kidney graft loss is determined by a large set of variables interacting across the different stages of the transplantation process. This…
  • 2019 American Transplant Congress

    Interpretable Post-Transplant Graft Failure Prediction Using Decision Tree Neural Networks

    J. N. Valdez1, T. Fu1, J. Hogan2, S. Adhikary1, M. Arenson2, R. Zhang2, X. Zhang3, K. Li2, A. B. Adams2, R. E. Patzer2, J. Sun1

    1Georgia Institute of Technology, Atlanta, GA, 2Emory University, Atlanta, GA, 3University of Michigan, Ann Arbor, MI

    *Purpose: Various predictive models identify kidney transplant (KTx) recipients at high risk of graft failure (GF), but comparisons across statistical approaches for a full range…
  • 2019 American Transplant Congress

    Predicting Post Liver Transplant 30-Day Readmission Using Deep Neural Network Model

    S. K. Niazi1, H. O. Park2, R. E. Carter3, A. Keaveny4, T. Schneekloth5, A. Spaulding6, D. Harnois4, P. F. Moreno-Franco7, E. Vargas6, T. Rummans1, C. Taner7

    1Psychiatry & Psychology, Mayo Clinic, Jacksonville, FL, 2Enterprise Analytics, Mayo Clinic, Rochester, MN, 3Health Sciences Research, Mayo Clinic, Jacksonville, FL, 4GI & Hepatology, Mayo Clinic, Jacksonville, FL, 5Psychiatry & Psychology, Mayo Clinic, Rochester, MN, 6Health Services Research, Mayo Clinic, Jacksonville, FL, 7Transplantation, Mayo Clinic, Jacksonville, FL

    *Purpose: Liver transplantation (LT) is a complex, expensive process and requires multidisciplinary care. A significant portion of the estimated $735,000 LT cost can be attributed…
  • 2018 American Transplant Congress

    Multidisciplinary Approach to Prevention of Cytomegalovirus (CMV) Complications in Kidney and Liver Transplant Recipients

    S. Shoham,1 S. Anderson,2 R. Avery,1 M. Belden,3 L. Boyer,3 W. Cochran,3 N. Desai,1 M. Holechek,3 E. Kraus,1 J. Langlee,3 P. Spitz,2 K. Marr.1

    1Johns Hopkins University School of Medicine, Baltimore, MD; 2IT@JH Epic, JHMI: Johns Hopkins Health System, Baltimore, MD; 3Comprehensive Transplant Center, JHMI: Johns Hopkins Hospital, Baltimore, MD.

    Background: CMV infection can be prevented in most SOT recipients providing that a prevention protocol is followed. We discovered that our center's protocol, which includes…
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