2018 American Transplant Congress
Program-Specific Transplant Rate Ratios: Association with Allocation Priority at Listing and Posttransplant Outcomes
The Scientific Registry of Transplant Recipients (SRTR) has updated the transplant rate and waitlist mortality risk-adjustment models to include a wider range of candidate characteristics…2018 American Transplant Congress
A 5-Tier System for Categorizing Program-Specific Adjusted Transplant and Waitlist Mortality Rate Ratios
SRTR may begin reporting tiers for program-specific transplant and waitlist mortality rate ratios. A 3-tier system based on statistical hypothesis testing has several deficiencies. Waitlist…2018 American Transplant Congress
Informed Clustering of Donor Service Areas for Better Benchmarking
United Network for Organ Sharing, Richmond, VA.
The 58 Donor Service Areas (DSA) represent territories of varying geographic sizes, densities and populations. The intention of this project is to group DSA based…2018 American Transplant Congress
Prediction of 90 Days Readmission after Kidney Transplantation Including Natural Language Processing
Early identification of hospital readmission for End Stage Renal Disease (ESRD) patients who obtained kidney transplantation potentially help decrease their risk of readmission after transplantation,…2018 American Transplant Congress
Novel Approach to Molecular Testing Using Routine Diagnostic Tissue
1University of Glasgow, Glasgow, United Kingdom; 2Columbia University, New York.
Currently, molecular diagnostics in kidney transplantation requires dedicated fresh tissue. This requirement limits use in mainstream clinical settings due to perceived increased patient risk in…2018 American Transplant Congress
Transplant Psychiatry- A Growing Subspecialty. Introducing the Transplant Psychiatry Special Interest Group from the Academy of Psychosomatic Medicine
Purpose: 1. To inform the AST community about the activities of Transplant Psychiatry Special Interest Group that has been operating within the Academy of Psychosomatic…2018 American Transplant Congress
A Novel, Dose-Adjusted Tacrolimus Intrapatient Variability Model Identifies High-Risk Kidney Transplant Recipients Better Than Existing Methodologies
Astellas Pharma Global Development, Inc., Northbrook.
Intrapatient variability (IPV) of tacrolimus trough concentration (TTC) is a risk factor for inferior transplant outcomes. However, assessing IPV is problematic, relying on fixed dose…2018 American Transplant Congress
Program-Specific Survival from Listing: Variability and Association with Pretransplant and Posttransplant Metrics
Transplant program performance assessment has traditionally focused on posttransplant outcomes. However, the survival benefit conferred by transplant offers a compelling reason to broaden program assessment…2018 American Transplant Congress
Evaluation of FlowDSA Crossmatch for Detection of Donor-Specific HLA Antibodies
Background: Donor-specific HLA antibodies (DSA) are detected by different crossmatch techniques. Flow cytometric crossmatching (FCXM) is sensitive method, but it is subject to false (+)…2018 American Transplant Congress
Immune Phenotyping in a Pediatric Multicenter Transplant Study: Suitability of a Pre-Formulated Dry Antibody Panel System
Background:Flow cytometric immune-phenotyping is influenced by cryopreservation and inter-laboratory variability limiting comparability in multi center studies. The Duraclone™ system (DC) provides optimized pre-mixed dry antibody…