2018 American Transplant Congress
Novel Approach to Molecular Testing Using Routine Diagnostic Tissue
1University of Glasgow, Glasgow, United Kingdom; 2Columbia University, New York.
Currently, molecular diagnostics in kidney transplantation requires dedicated fresh tissue. This requirement limits use in mainstream clinical settings due to perceived increased patient risk in…2018 American Transplant Congress
Transplant Psychiatry- A Growing Subspecialty. Introducing the Transplant Psychiatry Special Interest Group from the Academy of Psychosomatic Medicine
Purpose: 1. To inform the AST community about the activities of Transplant Psychiatry Special Interest Group that has been operating within the Academy of Psychosomatic…2018 American Transplant Congress
A Novel, Dose-Adjusted Tacrolimus Intrapatient Variability Model Identifies High-Risk Kidney Transplant Recipients Better Than Existing Methodologies
Astellas Pharma Global Development, Inc., Northbrook.
Intrapatient variability (IPV) of tacrolimus trough concentration (TTC) is a risk factor for inferior transplant outcomes. However, assessing IPV is problematic, relying on fixed dose…2018 American Transplant Congress
Program-Specific Survival from Listing: Variability and Association with Pretransplant and Posttransplant Metrics
Transplant program performance assessment has traditionally focused on posttransplant outcomes. However, the survival benefit conferred by transplant offers a compelling reason to broaden program assessment…2018 American Transplant Congress
Evaluation of FlowDSA Crossmatch for Detection of Donor-Specific HLA Antibodies
Background: Donor-specific HLA antibodies (DSA) are detected by different crossmatch techniques. Flow cytometric crossmatching (FCXM) is sensitive method, but it is subject to false (+)…2018 American Transplant Congress
Immune Phenotyping in a Pediatric Multicenter Transplant Study: Suitability of a Pre-Formulated Dry Antibody Panel System
Background:Flow cytometric immune-phenotyping is influenced by cryopreservation and inter-laboratory variability limiting comparability in multi center studies. The Duraclone™ system (DC) provides optimized pre-mixed dry antibody…2018 American Transplant Congress
AT1R Antibody Analysis: High Proportion of Non-Specific Reactivity?
INTRODUCTION:The angiotensin II type 1 receptor (AT1R) is expressed on vascular endothelium. AT1R antibodies (Ab) have been studied to examine their relevance in renal and…2018 American Transplant Congress
Multidisciplinary Approach to Prevention of Cytomegalovirus (CMV) Complications in Kidney and Liver Transplant Recipients
Background: CMV infection can be prevented in most SOT recipients providing that a prevention protocol is followed. We discovered that our center's protocol, which includes…2018 American Transplant Congress
Program-Specific Transplant Rate Ratios: Association with Allocation Priority at Listing and Posttransplant Outcomes
The Scientific Registry of Transplant Recipients (SRTR) has updated the transplant rate and waitlist mortality risk-adjustment models to include a wider range of candidate characteristics…2018 American Transplant Congress
A 5-Tier System for Categorizing Program-Specific Adjusted Transplant and Waitlist Mortality Rate Ratios
SRTR may begin reporting tiers for program-specific transplant and waitlist mortality rate ratios. A 3-tier system based on statistical hypothesis testing has several deficiencies. Waitlist…
American Transplant Congress abstracts