2016 American Transplant Congress
An Analysis of Non-Tuberculous Mycobacteria (NTM) Infection and Colonization in Lung Transplant Recipients (LTRs) Post-Transplant: A Single Center Matched Cohort Study.
PurposeNTM is a common infection after Lung transplantation. The role of presence of granuloma in the explanted lungs of LTRs in subsequent development of infection…2016 American Transplant Congress
MiRNA-200b Inhibits Epithelial-Mesenchymal Transition in TGF-β1 Induced Human Bronchial Epithelial Cells.
Institute of Cellular Medicine, Newcastle University, Newcastle Upon Tyne, United Kingdom.
The role of TGF-β1 in mediating extracellular matrix remodeling during the pathogenesis of lung fibrosis has been well defined. Dysregulated expression of miRNA is increasingly…2016 American Transplant Congress
Susceptibility Patterns of Pre-Transplant Pseudomonas and Post-Lung Transplant Outcomes in Patients with Cystic Fibrosis.
Background: The impact of pre-lung transplant (LT) pan-drug-resistant Pseudomonas aeruginosa (PDR PsA) colonization on post-LT mortality and bronchiolitis obliterans syndrome (BOS) rates in cystic fibrosis…2016 American Transplant Congress
The Apoptosis of the Tracheal Epithelia Increase the Recipient's MSCs Derived Myofibroblasts in Allografts to Exacerbate Obliterative Bronchiolitis After Tracheal Transplantation in Mice.
Background: The long-term outcome of lung transplantation is impeded by obliterative bronchiolitis (OB). However, the current treatment cannot effectively prevent the process of OB. The…2016 American Transplant Congress
Achieving Timely Therapeutic Mycophenolic Acid Levels in Pediatric Lung Transplant Patients.
Texas Children's Hospital, Houston, TX.
The purpose of this study was to determine the appropriate initial dose of mycophenolate mofetil (MMF) in pediatric cystic fibrosis (CF) and non-CF lung transplant…2016 American Transplant Congress
Are We Refusing Good Organs? Outcomes of Ventilator Management of Sub-Optimal Lung Donors.
PurposeOptimizing donor lung function is essential for organ acceptance and successful lung transplantation (LTx). We hypothesized that ventilator management of sub-optimal donor lungs, PaO2<300 mmHg,…2016 American Transplant Congress
Outcomes in Lung Transplant Patients Requiring Extracorporeal Membrane Oxygenation (ECMO) in the Perioperative Period.
Cardiovascular Surger, Hospital of the University of Pennsylvania, Philadelphia, PA.
Objective As ECMO therapy is increasingly used to bridge high-risk patients with end-stage respiratory failure to lung transplantation, outcomes of this strategy employed in the…2016 American Transplant Congress
Abrogating Donor-Derived Myd88 Signaling Impairs the Recruitment of Recipient Neutrophils and CD8 T Cells into Lung Allografts in Mice.
Objectives: Transplant ischemia reperfusion injury (IRI) mediated primary graft dysfunction (PGD) remains the predominant cause of short- and long-term graft loss in lung transplantation. This…2016 American Transplant Congress
Hospitalizations, Survival, and Complications: 1-Year Outcomes for Elderly Lung Transplant Recipients.
Houston Methodist Hospital, Houston, TX.
Purpose: In 2014, The International Society for Heart and Lung Transplantation published consensus guidelines listing age greater than 65 years as a relative contraindication to…2016 American Transplant Congress
BATF Deficiency in Tolerant Lung Allograft Recipients Are Resistant to Anti-MHC and Anti-Self-Antigen Mediated Pathogenesis of Obliterative Airway Disease.
Antibodies (Abs) to donor MHC and lung self-antigens (SAgs) administered following induction of lung allograft tolerance by co-stimulation blockade can result in breaking of tolerance…
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