ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Lung transplantation"

  • 2016 American Transplant Congress

    Hospitalizations, Survival, and Complications: 1-Year Outcomes for Elderly Lung Transplant Recipients.

    N. Casciello, A. Fuentes, J. Krisl, N. Sinha, T. Kaleekal.

    Houston Methodist Hospital, Houston, TX.

    Purpose: In 2014, The International Society for Heart and Lung Transplantation published consensus guidelines listing age greater than 65 years as a relative contraindication to…
  • 2016 American Transplant Congress

    BATF Deficiency in Tolerant Lung Allograft Recipients Are Resistant to Anti-MHC and Anti-Self-Antigen Mediated Pathogenesis of Obliterative Airway Disease.

    Z. Xu,1,2 X. Lin,1 M. Gunasekaran,1,2 M. Sharma,1,2 A. Gelman,1 T. Mohanakumar.1,2

    1Washington Univ Sch Med, St. Louis, MO; 2Norton Thoracic Institute - St. Joseph's Hospital, Phoenix, AZ.

    Antibodies (Abs) to donor MHC and lung self-antigens (SAgs) administered following induction of lung allograft tolerance by co-stimulation blockade can result in breaking of tolerance…
  • 2016 American Transplant Congress

    Comparison of Clinical Outcomes in Lung Transplant Patients with and without Preoperative Pulmonary Hypertension.

    A. Kalya, M. Boga, S. Dasyam, R. Walia, M. Smith, R. Bremner, A. Omar, V. Patel, E. Kuo, J. Huang, S. Hashimi.

    St. Joseph's Hospital and Medical Center, Phoenix.

    Purpose: End-stage lung disease patients (pts) who undergo lung transplantation (LTx) with an elevated mean pulmonary artery pressure (mPAP) are known to have adverse outcomes.…
  • 2016 American Transplant Congress

    Obliterative Bronchiolitis Following Lung Transplantation Is Preceded by Depletion of Airway Submucosal Glands and Basal Stem Cells.

    A. Swatek, A. Crooke, P. Anderson, T. Lynch, M. Ivanovic, J. Klesney-Tait, M. Eberlein, T. Pena, J. Engelhardt, K. Parekh.

    University of Iowa, Iowa City, IA.

    Background: Obliterative bronchiolitis (OB), a major cause of morbidity and mortality following lung transplantation, is characterized by progressive fibrosis of distal airways. We hypothesized that…
  • 2016 American Transplant Congress

    The Effect of Body Mass Index on Lung Transplant Outcomes.

    M. Kashem,1 A. Shiose,1 J. Abraham,1 N. Dean,1 S. Breves,1 F. Cordova,2 N. Patel,2 T. Yoshizumi,1 G. Criner,2 Y. Toyoda.1

    1Division of Cardiovascular Surgery, Temple University, Philadelphia, PA; 2Department of Thoracic Medicine and Surgery, Temple University, Philadelphia, PA.

    Background: Lung transplant (LTx) has the potential to effectively extend the life expectancy for patients with end-stage lung disease. Both high and low body mass…
  • 2016 American Transplant Congress

    Rapamycin Encapsulated Nanoparticles as Pre-Treatment in Lung Transplantation.

    G. Bazzle,1 S. Dixit,2 K. Patel,3 A.-M. Broome,2 S. Nadig,1,3 C. Atkinson.1,3

    1Microbiology and Immunology, Medical University of South Carolina, Charleston, SC; 2Department of Radiology, Medical University of South Carolina, Charleston, SC; 3Department of Surgery, Medical University of South Carolina, Charleston, SC.

    Introduction: While short-term lung transplant outcomes have improved over the years, long-term survival rates remain stagnant. Many injuries occur to the donor organ before transplantation,…
  • 2016 American Transplant Congress

    Pre-Transplant Prostate Cancer in Lung Transplant Recipients and Impact on Post-Transplant Morbidity and Mortality.

    S. Ajani, M. Valapour, M. Budev.

    Respiratory Institute, Cleveland Clinic, Cleveland, OH.

    PurposeAssess the impact of pre-transplant prostate cancer on mortality after lung transplant and the incidence of recurrence of prostate cancer after transplant.MethodsThe electronic medical records…
  • 2016 American Transplant Congress

    Exosomes with Lung Associated Self-Antigens (Collagen V and K alpha 1 Tubulin): Role in Rejection Following Human Lung Transplantation.

    M. Gunasekaran,1,2 Z. Xu,1,2 D. Nayak,1,2 M. Sharma,1,2 R. Hachem,1 T. Mohanakumar.1,2

    1Surgery, Pathology & Immunology, & Medicine, Washington Univ Sch Med, St. Louis, MO; 2Norton Thoracic Institute - St. Joseph's Hospital, Phoenix, AZ.

    Immune response to HLA and non-HLA antigens play a significant role in the development of chronic and acute rejection (AR), bronchiolitis obliterans syndrome (BOS), following…
  • 2016 American Transplant Congress

    The Role of Palliative Care in the Thoracic Transplant Multidisciplinary Care Team: Barriers and Benefits.

    A. Manfredi,1 C. Toevs.2

    1Loyola University Medical Center, Maywood, IL; 2Terre Haute Regional Hospital, Terre Haute, IN.

    PURPOSE: Patients under consideration for or who have undergone lung and heart transplantation experience many symptoms, including dyspnea, anxiety, pain and caregiver burden. Integration of…
  • 2016 American Transplant Congress

    High-Risk Age Window for Graft Loss in Pediatric Lung and Heart Transplant Recipients.

    B. Orandi, X. Luo, K. Van Arendonk, R. Higgins, D. Segev.

    Johns Hopkins University, Baltimore.

    Late adolescence and early adulthood is a high-risk age window for pediatric kidney graft loss, though not for pediatric liver graft loss. It is unknown…
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