ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Lung transplantation"

  • 2020 American Transplant Congress

    Donor Lung Travel Distance and Time

    C. Lehr1, M. Skeans2, M. Valapour1, E. Lease3

    1Cleveland Clinic, Cleveland, OH, 2SRTR, Minneapolis, MN, 3University of Washington, Seattle, WA

    *Purpose: With the policy change from donation service area (DSA) to 250 nautical miles (NM) as the first unit of US lung allocation, distances between…
  • 2020 American Transplant Congress

    Phage Therapy for Mycobacterium Abscessus (Mab) Infection after Lung Transplant (LT)

    W. Garner1, R. Dedrick2, C. Guerrero2, M. Morrell1, J. D'Cunha3, P. Sanchez1, G. Hatfull2, G. Haidar1

    1University of Pittsburgh Medical Center, Pittsburgh, PA, 2University of Pittsburgh, Pittsburgh, PA, 3Mayo Clinic Arizona, Phoenix, AZ

    *Purpose: LT recipients with Mab infections have poor outcomes. We describe a patient with refractory Mab infection treated with mycobacteriophage therapy.*Methods: A 56-year-old woman with…
  • 2020 American Transplant Congress

    First Report of Successful CD38-Antagonist Daratumumab Augmented Carfilzomib-Based Treatment of Refractory Definite AMR of the Lung Allograft

    M. N. Kildea1, C. R. Ensor1, J. Kim1, L. Bogar1, D. Colella1, R. D. Davis1, M. Marschner1, A. Zeevi2, N. Soe1, C. Gries1

    1AdventHealth, Orlando, FL, 2University of Pittsburgh, Pittsburgh, PA

    *Purpose: Antibody-mediated rejection (AMR) after lung transplant (LT) is associated with early progressive chronic lung allograft dysfunction (CLAD) and death. Therapeutic regimens remain poorly evaluated.…
  • 2020 American Transplant Congress

    Changes in Health-Related Quality of Life During the First Year in Lung Transplantation Recipients

    H. Zhou, J. Chen

    Lung Transplant Center, Wuxi People’s Hospital, Wuxi, China

    *Purpose: This longitudinal study was conducted to recognize the tracks of HRQOL during the first year after transplantation and the main factors associated with HRQOL…
  • 2020 American Transplant Congress

    Safety and Efficacy of Prophylactic Valganciclovir Dosing after Solid Organ Transplant

    K. Gandhi, D. Masic, M. Santarossa, F. Albarillo, N. Clark, G. Reid

    Loyola University Medical Center, Maywood, IL

    *Purpose: At centers where antiviral prophylaxis is used after solid organ transplant, valganciclovir is administered for the prevention of cytomegalovirus (CMV). At Loyola University Medical…
  • 2020 American Transplant Congress

    Green Channel of Human Organ Transport (GCHOT) Improved the Utilization Rate of Chinese Citizens’ Donated Lungs: A Single-Center Data Analysis

    J. Chen, X. Li, C. Hu, F. Liu

    Wuxi Lung Transplant Center, Wuxi, China

    *Purpose: Lung transplantation in China has been developing for over forty years. Wuxi lung transplant center has the largest lung transplant (LT) volume nationwide. It…
  • 2020 American Transplant Congress

    Statin Use May Be Associated with Lower Risk of Invasive Aspergillosis in Lung Transplant Recipients

    A. Perez Cortes Villalobos, F. Foroutan, S. Davoudi, T. Martinu, J. Tikkanen, L. Singer, S. Keshavjee, S. Husain

    University Health Network, Toronto, ON, Canada

    *Purpose: Statins are competitive inhibitors of HMG-CoA reductase, that catalyses the conversion of HMG-CoA to mevalonate, which is involved in the synthesis of cholesterol in…
  • 2020 American Transplant Congress

    Single Center Snapshot Experience of dd-cfDNA in Lung Transplantation

    D. Levine, P. Ong, D. De Armond, E. Sako

    University of Texas Health San Antonio, San Antonio, TX

    *Purpose: Chronic lung allograft dysfunction (CLAD) is the primary etiology of graft failure and associated with poor survival post lung transplantation (LT). Risk factors for…
  • 2020 American Transplant Congress

    Circulatory Extracellular Vesicles from Lung Allograft Recipients with Chronic Lung Allograft Dysfunction Can Induce LKB1 Dependent Epithelial-Mesenchymal Transition

    M. Rahman, S. Angara, A. Arjuna, M. Smith, R. Bremner, T. Mohanakumar

    Norton Thoracic Institute, St. Joseph’s Hospital and Medical Center, Phoenix, AZ

    *Purpose: Extracellular vesicles (EVs) play important role in physiological and pathological conditions. Recently we demonstrated that circulating exosomes (EVs) with lung self-antigens (SAgs) play important…
  • 2020 American Transplant Congress

    Improved Platelet Sequestration with Humanization of Von Willebrand Factor in Pig Xenogeneic Lung Perfusion Model

    M. R. Connolly1, L. Burdorf1, Z. Abady1, S. Sendil2, E. Redding2, B. Cerel1, S. Pratts1, C. Phelps3, W. Eyestone3, D. Ayares3, A. Azimzadeh1, R. N. Pierson III1

    1Center for Transplantation Sciences, Massachusetts General Hospital, Boston, MA, 2University of Maryland, Baltimore, Baltimore, MD, 3Revivicor, Blacksburg, VA

    *Purpose: Von Willebrand factor (vWF) is an important element of hemostasis and when activated, mediates platelet adhesion and promotes platelet aggregation under shear stress conditions.…
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