2020 American Transplant Congress
Granulocyte Colony Stimulating Factor: Trigger of Rejection in Lung Transplantation?
*Purpose: Granulocyte colony stimulating factor (GCSF) is a management strategy for post-transplant neutropenia, but may increase the risk of rejection in lung transplant recipients (LTRs).…2020 American Transplant Congress
Pleural Exosome Mediated Donor Antigen Trafficking Into Mediastinal Lymph Nodes Represents a Novel Pathway of Recipient T Cell Activation in Lung Transplantation
*Purpose: Studies in lung transplant models suggest that reestablishment of lymphatic continuum of pulmonary allograft via lymphangiogenesis is required for selective trafficking of donor antigen…2020 American Transplant Congress
Characteristics and Outcomes of Patients with Cystic Fibrosis Receiving Lung Transplant with and without ECMO Bridge – A Single Center Experience
Pulmonary & Critical Care, USC, Los Angeles, CA
*Purpose: ECMO is a viable bridge to lung transplantation (LTx) for end-stage cystic fibrosis (CF) patients refractory to traditional medical support. We sought to identify…2020 American Transplant Congress
Survival after Lung Transplantation by Discharge Immunosuppressive Regimen: An Analysis of Organ Procurement and Transplantation Network Data
*Purpose: As the optimal immunosuppressive (IS) regimen after lung (LU) transplant (TX) is unknown, we conducted an analysis to compare the effect of four different…2020 American Transplant Congress
Single Cell Gene Profiling Highlights Novel B Cell Populations Associated with the Development of Bronchiolitis Obliterates Syndrome after Lung Transplantation
*Purpose: The occurence of bronchiolitis obliterans syndrome (BOS) accounts for a poor long term prognosis after lung transplantation (LTx). Despite immunosuppressive T cell-targeting therapies the…2020 American Transplant Congress
Transpulmonary Gradient as a Predictor for Outcomes after Single Lung Transplantation in Patients with Pulmonary Hypertension
*Purpose: End stage lung disease is commonly associated with pulmonary artery hypertension (PAH). In a donor restrictive environment, offering patients single over double lung transplants…2020 American Transplant Congress
Isavuconazole (ISA) versus Voriconazole (VOR) Prophylaxis (px) in Lung Transplant Recipients (LTR)
University of Pittsburgh Medical Center, Pittsburgh, PA
*Purpose: IFI is a significant complication following lung transplant (LT). VOR was universal antifungal (AF) px in our LT program from 2004-09/2015, at which time…2020 American Transplant Congress
Lung Transplantation for Patients with Pneumoconiosis in China: A Multicenter Experience from 2015-2019
*Purpose: The pneumoconiosis are parenchymal lung diseases that arise from inhalation of dusts. And lung transplantation is an effective method for the treatment of end-stage…2020 American Transplant Congress
Sirolimus Plus Tacrolimus Immunosuppression, with or without Mycophenolate Mofetil, May Improve Survival after Bronchiolitis Obliterans Syndrome in Lung Transplant Patients
University of Maryland School of Medicine, Baltimore, MD
*Purpose: There are very few ways to improve survival after bronchiolitis obliterans syndrome (BOS), the leading cause of death in lung transplant patients. Two long-term…2020 American Transplant Congress
Eosinophils Maintain Lung Allograft Tolerance by Sequestering CD8+ T Cells in Bronchial Associated Lymphoid Tissue
*Purpose: It has been recently described that eosinophils can facilitate immunosuppression-mediated acceptance of murine lung allografts. But the role of eosinophils in long term maintenance…
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