2022 American Transplant Congress
Spleen-Preserving Total Pancreatectomy with Islet Autotransplantation with Complete Preservation of the Splenic Arterial and Venous Supply Does Not Impact Islet Yield and Function
Baylor University Medical Center, Dallas, TX
*Purpose: Typically, Total Pancreatectomy with Islet Autotransplantation (TPIAT) includes splenectomy. Spleen sparing TPIAT was described in the literature using the Warshaw technique, with proximal ligation…2022 American Transplant Congress
The Application of Activated Stem Cells from Human Exfoliated Deciduous Teeth (SHED) in Islet Transplantation for Novel Immunosuppressive Therapy
*Purpose: While various attempts have been made to improve the efficiency of islet transplantation, we have been working on the analysis of the mechanism of…2022 American Transplant Congress
Biological Functions of Circulating miRNAs in Patients with Chronic Pancreatitis Undergoing Total Pancreatectomy with Islet Autotransplantation
*Purpose: Our previous reports showed that in patients with Chronic Pancreatitis (CP), specific microRNAs (miRNA) were elevated in circulation before, during islet infusion and after…2022 American Transplant Congress
Tacrolimus Induces Dedifferentiation of Pancreatic Beta Cells by Inhibition of Calcineurin/NFATc2 and Islet Cell Differentiation Genes
*Purpose: Tacrolimus (FK506) is a potent immunosuppressant widely used for solid organ transplantation to prevent lymphokine gene expression by inhibiting calcineurin (CN) and its downstream…2022 American Transplant Congress
Evidence for Improved Quality of Life Among Chronic Pancreatitis Patients Undergoing Total Pancreatectomy with Islet Autotransplantation Using EORTC QLQ-C30 and QLQ-PAN 26
Baylor University Medical Center, Dallas, TX
*Purpose: Total pancreatectomy with islet autotransplantation (TPIAT) is the treatment of choice to preserve endocrine function, alleviate pain, reduce or eliminate chronic narcotic use and…2021 American Transplant Congress
Psychosocial Outcomes 1-year Post Total Pancreatectomy and Autologous Islet Cell Transplant
*Purpose: A paucity of research regarding the psychosocial outcomes after-total pancreatectomy and autologous islet cell transplantation exists. The aim of the study was to examine…2021 American Transplant Congress
Diffuse Calcification Pattern in Chronic Pancreatitis Has Two Aspects in Total Pancreatectomy with Islet Autotransplantation: Bad Sign for Islet Graft Function and Good Sign for Pain Relief
Baylor University Medical Ctr, Dallas, TX
*Purpose: Chronic pancreatitis (CP) is characterized by progressive inflammation and fibrosis of the pancreas. The diagnosis of CP is based on pancreatic calcifications, ductal dilatation,…2021 American Transplant Congress
Comparative Outcomes of TPIAT in African American and Caucasian Patients with Chronic Pancreatitis
Virginia Commonwealth University, Richmond, VA
*Purpose: Total pancreatectomy with islet auto-transplantation (TPIAT) is becoming the standard of care for patients with chronic pancreatitis, as it provides pain relief and improved…2021 American Transplant Congress
TPIAT Outcomes in Diabetic and Non-diabetic Patients
Virginia Commonwealth University, Richmond, VA
*Purpose: Total pancreatectomy with islet auto-transplant (TPIAT) has become a mainstay treatment for patients who suffer from refractory chronic pancreatitis. It has consistently been shown…2021 American Transplant Congress
Endocrine Cell Identity and HOMA-B In Patients with Chronic Pancreatitis Undergoing Islet Auto-transplantation
1Surgery, Houston Mehodist Hospital, Houston, TX, 2Surgery, Houston Mehodist, Houston, TX
*Purpose: Islet identity loss is an emergent factor in dysglycemia in diabetes, islet transplantation, and chronic pancreatitis (CP). Pancreatectomy and islet auto-transplantation (PIAT) for CP…
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