Spleen-Preserving Total Pancreatectomy with Islet Autotransplantation with Complete Preservation of the Splenic Arterial and Venous Supply Does Not Impact Islet Yield and Function
Baylor University Medical Center, Dallas, TX
Meeting: 2022 American Transplant Congress
Abstract number: 1175
Keywords: Islets, Pancreatitis, Surgery
Topic: Clinical Science » Pancreas » 65 - Pancreas and Islet: All Topics
Session Name: Pancreas and Islet: All Topics
Session Type: Poster Abstract
Date: Sunday, June 5, 2022
Session Time: 7:00pm-8:00pm
Presentation Time: 7:00pm-8:00pm
Location: Hynes Halls C & D
*Purpose: Typically, Total Pancreatectomy with Islet Autotransplantation (TPIAT) includes splenectomy. Spleen sparing TPIAT was described in the literature using the Warshaw technique, with proximal ligation of the splenic artery, which can cause splenic infarcts. We hereby report spleen sparing TPIAT with preservation of the splenic artery and vein (SPTP), thus with full preservation of the blood supply to the spleen and improved blood supply to the greater curvature of the stomach.
*Methods: We compared the metabolic and clinical outcomes in patients who underwent TPIAT between 2015 to 2021 with or without splenectomy.
*Results: A total of 95 patients were included in the study, of which 18 underwent SPTP. Table 1 summarizes group differences in clinical outcomes between TPIAT with splenectomy versus SPTP. The two study groups had similar demographics and metabolic parameters. Despite early ligation of the arteries to the pancreatic tail, the islet yield and the short term and long term metabolic outcomes were similar.
*Conclusions: Spleen sparing TPIAT with full arterial and venous preservation has no adverse impact in islet yield or function while avoiding possible morbidity post-splenectomy.
To cite this abstract in AMA style:Coluzzi M, Naziruddin B, Saracino G, Testa G, Beecherl E, Onaca N. Spleen-Preserving Total Pancreatectomy with Islet Autotransplantation with Complete Preservation of the Splenic Arterial and Venous Supply Does Not Impact Islet Yield and Function [abstract]. Am J Transplant. 2022; 22 (suppl 3). https://atcmeetingabstracts.com/abstract/spleen-preserving-total-pancreatectomy-with-islet-autotransplantation-with-complete-preservation-of-the-splenic-arterial-and-venous-supply-does-not-impact-islet-yield-and-function/. Accessed March 26, 2023.
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