2016 American Transplant Congress
The Treatment of Borderline Lesion in Protocol Biopsies Did Not Improve the Outcome in Kidney Transplant Recipients.
Introduction. Up to 30% of patients with protocol biopsies and stable renal function have borderline lesions. His relationship with acute rejection remains uncertain, as does…2016 American Transplant Congress
Implications of Subclinical Borderline Acute Cellular Rejection Detected in Protocol Biopsies on Graft Outcomes.
Background: The effects of subclinical borderline acute cellular rejection (BACR-defined as I1T1 per Banff criteria) detected in protocol biopsies (Bx) on subsequent graft function and…2016 American Transplant Congress
Renal Graft Survival According to Banff 2013 Diagnostic Categories in Indication Biopsies.
1Nephrology, Hospital del Mar, Barcelona, Spain; 2Pathology, Hospital del Mar, Barcelona, Spain.
The impact of acute rejection in kidney graft survival is well known, but the prognosis of other diagnosis is uncertain. We evaluated the frequency and…2016 American Transplant Congress
Is Pretransplant Determination of Hepatocellular Carcinoma Tumor Grade Using Needle Biopsy Reliable for Transplant Candidate Selection? Analysis of 217 Liver Transplant Recipients.
Department of Surgery, UCLA, Los Angeles, CA.
Objective: Despite the prognostic significance of tumor grade and vascular invasion for patients with hepatocellular carcinoma (HCC), preoperative needle biopsy (PNB) is not routinely utilized…2016 American Transplant Congress
Elevated Intragraft Expression of Innate Immunity and Cell Death-Related Markers Characterizes Deceased Donor Conditions and Is a Risk Factor for Adverse Graft Outcome.
Background: The innate immune response is increasingly being recognized in allograft injury after kidney transplantation. We aimed to establish the relationship of innate immune gene…2016 American Transplant Congress
The Effect of Everolimus and Tacrolimus Exposure Levels on Renal Histology Parameters 6 Months Post-Transplantation.
We examined renal histology scores in patients with different exposure levels of everolimus (EVR) and tacrolimus (TAC) over 6 months.Renal transplant patients (N=613) were randomized…2016 American Transplant Congress
The Quilty Effect in Pediatric Heart Transplant Recipients.
Purpose: The Quilty effect is defined as the presence of a nodular endocardial infiltrate of lymphocytes in an endomyocardial biopsy (EMB), and has been described…2016 American Transplant Congress
IFTA Is Linked to Urinary Microbiome Changes.
Department of Molecular and Experimental Medicine, The Scripps Research Institute, La Jolla, CA.
Purpose: The microbiome is important to human health and alteration may lead to aberrant immunity and disease. Interstitial fibrosis and tubular atrophy(IFTA) occurs in 20%…2016 American Transplant Congress
Long-Term Deterioration of Graft Function (DeKAF) Study: Histologic Interpretation of Cross-sectional vs Prospective Cohorts.
1U of MN, Mpls, MN; 2U IA, Iowa City, IA; 3Mayo, Rochester, MN.
The major aim of the DeKAF study was to define previously unidentified phenotypes resulting in late graft dysfunction and loss (GL). Two cohorts were developed,…2016 American Transplant Congress
Everolimus with Low-Dose Tacrolimus vs. a Standard Immunosuppressive Regimen: Renal Histology at 6 Months in De Novo Renal Transplant Patients.
Morphologic changes in transplant protocol biopsies provide early evidence of renal damage. This study examined the renal histology of de novo patients 6 months post…
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