ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Biopsy"

  • 2016 American Transplant Congress

    Potential Kidney Donors with Asymptomatic Micorsocpic Hematuria: Histopathological Findings & Outcomes.

    E. Hassan,1,2 H. Aleid,1 T. Zulfiquar,1 I. Ibrahim,1,3 H. Almana.4

    1Department of Kidney & Pancreas Transplantation, King Faisal Specialist Hospital & Research Center, Riyadh, Saudi Arabia; 2Department of Nephrology, Fayoum University, Fayoum, Egypt; 3Department of Nephrology, Cairo University, Cairo, Egypt; 4Department of Anatomic Pathology, King Faisal Specialist Hospital & Research Center, Riyadh, Saudi Arabia.

    Background: Microscopic hematuria is not uncommon in potential kidney donors. After excluding urological causes, most of these donors require kidney biopsy to exclude glomerular lesions.…
  • 2016 American Transplant Congress

    A Quantitative CD45 Assay May Improve Diagnostic Accuracy of the Diagnosis of Acute Cellular Rejection in Transplant Kidney Biopsies.

    L. Laszik, S. Bowman, V. Walavalkar, F. Vincenti, Z. Laszik.

    UCSF, San Francisco.

    Purpose: We have previously shown that the total inflammatory load in transplant kidney biopsies (TxBx) can be determined with a high degree of accuracy using…
  • 2016 American Transplant Congress

    Kidney Transplant Recipient Adherence Measured by Proportion of Days Covered Is Associated with Late Biopsy Proven Acute Rejection.

    B. Hofmeyer, K. Look, J. Fose, A. Pulvermacher, A. Djamali, D. Hager.

    UW Health, Madison, WI.

    While medication non-adherence is a known risk factor for late “biopsy proven acute rejection (BPAR),” the Pharmacy Quality Alliance definition of “proportion of days covered…
  • 2016 American Transplant Congress

    Clinical Significance of Isolated v1 Arteritis in Renal Transplantation.

    D. Mikhail,1,3 J. Wei,3 D. Kleinsteuber,2 M. Gabril,2,3 A. Sener,1,3 M. Moussa,2,3 P. Luke.1,3

    1Department of Surgery, Division of Urology, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada; 2Department of Pathology and Laboratory Medicine, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada; 3Undergraduate Medicine, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada.

    INTRO: The presence of intimal arteritis (v) in renal transplant biopsies (Bx) establishes Grade II-III AVR (Acute Vascular Rejection) according to the Banff Classification. The…
  • 2016 American Transplant Congress

    Late Outcome Surrogate Score (LOSS) for Kidney Allograft Failure.

    B. Ho, L. Zhao, S. Montag, D. Ladner, M. Abecassis, A. Skaro.

    Comprehensive Transplant Center, Northwestern University, Chicago, IL.

    Background. Early outcomes following kidney transplant have steadily improved. Longer-term outcomes, while not the focus of regulatory oversight, are of vital importance. Clinical trials are…
  • 2016 American Transplant Congress

    Systematic Pathological Component Scores for Skin-Containing Vascularized Composite Allografts.

    I. Rosales,1 M. DeFazio,2 R. Foreman,1 D. Sachs,2 C. Cetrulo,2 D. Leonard,2,3 R. Colvin.1

    1Pathology, Massachusetts General Hospital, Boston; 2Transplantation Biology Research Center, Plastic and Reconstructive Surgery, Massachusetts General Hospital, Boston; 3Plastic and Reconstructive Surgery, Countess of Chester Hospital, Chester, United Kingdom.

    Successful application of skin-containing vascularized composite allografts (VCA) depends on accurate assessment of the graft status typically based on skin biopsies. A working classification (Banff…
  • 2016 American Transplant Congress

    Reversibility of Acute Kidney Rejection According to the Banff 2013 Classification: A Retrospective Cohort Study.

    A. Poulin,1 M. Dorais,2 L. Sénécal,3 S. Colette,3 H. Cardinal.1

    1CRCHUM, Montreal, QC, Canada; 2Statsciences, Montreal, QC, Canada; 3HMR, Montreal, QC, Canada.

    Background: Vascular involvement of the allograft has classically been regarded as a poor prognostic factor in acute kidney graft rejection. Cell-mediated endarteritis often coexists with…
  • 2016 American Transplant Congress

    Arteriolar Hyalinosis on Renal Transplant Protocol Biopsies Is Not Associated with Tacrolimus Exposure.

    S. Yilmaz,1 D. Shaffer,2 Y. Qazi,3 F. Shihab,4 K. McCague,5 D. Patel,5 F. Vincenti.6

    1University of Calgary, Calgary, AB, Canada; 2Vanderbilt University, Nashville, TN; 3University of Southern California, Los Angeles, CA; 4University of Utah, Salt Lake City, UT; 5Novartis Pharmaceuticals Corporation, East Hanover, NJ; 6University of California San Francisco, San Francisco, CA.

    Previous studies have implicated the development of arteriolar hyalinosis (AH) following kidney transplantation to chronic calcineurin inhibitor nephrotoxicity. Here, we examined the association between tacrolimus…
  • 2016 American Transplant Congress

    The Treatment of Borderline Lesion in Protocol Biopsies Did Not Improve the Outcome in Kidney Transplant Recipients.

    A. Flores-Mendoza, L. Marino-Vazquez, A. Guichard-Romero, N. Uribe-Uribe, R. Rivera-Marfil, A. Nuñez-Abreu, J. Alberu, L. Morales-Buenrostro.

    Nephrology, Transplantation and Pathology, National Institute of Medical Sciences and Nutrition SZ, Mexico, Distrito Federal, Mexico.

    Introduction. Up to 30% of patients with protocol biopsies and stable renal function have borderline lesions. His relationship with acute rejection remains uncertain, as does…
  • 2016 American Transplant Congress

    Implications of Subclinical Borderline Acute Cellular Rejection Detected in Protocol Biopsies on Graft Outcomes.

    Z. Zaky,1 C. Yu,1 N. Elfadawy,2 A. Chiesa-Vottero,1 L. Herlitz,1 S. Flechner,1 E. Poggio.1

    1Glickman Urological and Kidney institute, Cleveland Clinic, Cleveland, OH; 2Internal Medicine, Univ. Hospitals Case Medical Center, Cleveland, OH.

    Background: The effects of subclinical borderline acute cellular rejection (BACR-defined as I1T1 per Banff criteria) detected in protocol biopsies (Bx) on subsequent graft function and…
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