ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Biopsy"

  • 2016 American Transplant Congress

    Microarray Analysis of Transbronchial and Mucosal Biopsies in Lung Transplant Recipients Detects Molecular Changes of T-Cell Mediated Inflammation.

    K. Halloran,1 J. Chang,2 V. Ramassar,2 J. Weinkauf,1 A. Kapasi,1 D. Lien,1 J. Reeve,2 P. Halloran.1,2

    1Medicine, University of Alberta, Edmonton, Canada; 2Alberta Transplant Applied Genomics Centre, University of Alberta, Edmonton, Canada.

    Purpose: The main diagnostic platform for rejection in lung transplant recipients is histology of transbronchial biopsies (TBB), a test with a poor performance and safety…
  • 2016 American Transplant Congress

    Criteria for the Diagnosis of Microvascular Inflammation (MVI) in Kidney Transplant Biopsies (KTxBx).

    J. Grande,1 R. Leduc,2 The DeKAF Study Group.

    1Dept. of Lab Medicine & Pathology, Mayo Clinic College of Medicine, Rochester, MN; 2Division of Biostatistics, U. Minnesota School of Public Health, Minneapolis, MN.

    The presence of MVI (Banff glomerulitis "g" score and Banff peritubular capillary "ptc" score) in KTxBx, often related to antibody mediated rejection (AMR), is associated…
  • 2016 American Transplant Congress

    Results of Biopsies in Pancreas and Kidney-Pancreas Patients with Graft Dysfunction.

    P. Uva, L. Leon, E. Minue, I. Cabrera, A. Giunippero, M. Norese, M. Toniolo, E. Chuluyan, D. Casadei.

    Nephrology, Buenos Aires, Argentina.

    In pancreas transplantation there is no reliable laboratory test or imaging study for detection of graft rejection. There is an increasing interest in obtaining pancreas…
  • 2016 American Transplant Congress

    Management and Outcomes of Upper Extremity Deep Venous Thrombosis in Heart Transplant Patients.

    A. Panakos,1 D. Kramer,1 M. McCarey,1 P. Mather.2

    1Internal Medicine, Thomas Jefferson University Hospital, Philadelphia, PA; 2Cardiology, Thomas Jefferson University Hospital, Philadelphia, PA.

    Upper extremity deep venous thrombosis (UEDVT) is common in post-heart transplant (OHT) patients, likely due to their multiple intravascular catheters and post-surgical state. The clinical…
  • 2016 American Transplant Congress

    Comparison of C4d Deposition in Renal Biopsies with Luminex-Based C3d Single Antigen Bead (SAB) Detection.

    R. Pelletier,1 I. Balazs,2 P. Adams,3 P. Steller,3 N. DiPaola,4 L. Rankin,3 A. Diez,5 M. Henry.1

    1Surgery/Transplant, The Ohio State University Wexner Medical Center, Columbus, OH; 2Discovery Research, Immucor, Inc, Stamford, CT; 3Tissue Typing, The Ohio State University Wexner Medical Center, Columbus, OH; 4Methodist Hospital, Houston, TX; 5Nephrology, The Ohio State University Wexner Medical Center, Columbus, OH.

    Recent interest in characterizing the complement-fixing ability of post-transplant donor specific alloantibodies (DSA) resulted in the enhancement of luminex solid phase alloantibody assays to determine…
  • 2016 American Transplant Congress

    Age-Based High GFR Associates with Clinical Risk Among Potential Living Donors, but Only with Increased Nephron Number Among Approved Donors.

    H. Chakkera,1 E. Poggio,3 A. Denic,2 J. Mathew,2 W. Kremers,2 J. Larson,2 H. Amer,2 F. Cosio,2 M. Stegall,2 S. Taler,2 A. Rule.2

    1Mayo Clinic, Arizona; 2Mayo Clinic, Rochester; 3Cleveland Clinic, OH.

    Background:Association of high GFR with clinical and kidney structural characteristics among living donors has not been studied.Methods: Study cohort:potential kidney donors evaluated at Mayo Clinic…
  • 2016 American Transplant Congress

    Glomerular Capillary C4d Staining without Evidence of Rejection Is Associated with Worse Graft Function in ABO-Incompatible Kidney Transplantation.

    D. Toki,1 M. Inui,1 M. Okumi,2 H. Ishida,2 K. Setoguchi,1 T. Shimizu,2 K. Unagami,2 K. Tanabe.2

    1Urology, Tokyo Women's Medical University Yachiyo Medical Center, Chiba, Japan; 2Urology, Tokyo Women's Medical University, Tokyo, Japan.

    Objectives: C4d staining in the peritubular capillaries (C4d-PTC) is often observed without evidence of rejection in ABO-incompatible kidney transplantation (ABOI-KTx), and this phenomenon is generally…
  • 2016 American Transplant Congress

    Long-Term Death-Censored Graft Loss in the DeKAF Study.

    A. Matas,1 A. Fieberg,1 R. Leduc,1 F. Cosio,2 R. Gaston,3 R. Mannon,3 M. Cecka,4 D. Rush,7 B. Kasiske,5 S. Gourishankar,6 J. Connett,1 J. Grande.2

    1U of MN, Mpls, MN; 2Mayo, Rochester, MN; 3UAB, Birmingham, AB; 4UCLA, LA, CA; 5HCMC, Mpls, MN; 6U Alberta, Edmonton, AB, Canada; 7UMB, Winnipeg, MB, Canada.

    The aim of the Deterioration of Kidney Allograft Function study (DeKAF) was to identify and assess the pathologies of troubled kidney grafts, that is, those…
  • 2016 American Transplant Congress

    Urinary Exosomal Annexin A1 Is a Predictive Biomarker of Post Kidney Transplant Complications.

    H. Harada,1 T. Murakami,2 C. Yamamoto,2 K. Hotta,1 N. Fukuzawa,1 M. Mitsuhashi.2

    1Kidney Transplant Surgery, Sapporo City General Hospital, Sapporo, Japan; 2Hitachi Chemical Co. America, Ltd., Irvine, CA; 3Nanosomix, Inc., Aliso Viejo, CA.

    IntroductionMonitoring of kidney allograft condition is important. We had exhibited non-invasive diagnostic modality of post-kidney transplant complications using urine exosomal and microvesicule (EMV) mRNA of…
  • 2016 American Transplant Congress

    Characterization of Vascular Lesions in Living Donor Renal Transplant Implant Biopsies.

    F. Tinney Jr,1 L. Yessayan,2 M. Abouljoud,3 A. Patel.3

    1Wayne State University School of Medicine, Detroit, MI; 2Department of Nephrology, Henry Ford Hospital, Detroit, MI; 3Transplant Institute, Henry Ford Hospital, Detroit, MI.

    INTRODUCTION: Nephrosclerosis is often associated with pathological injury to kidneys resulting from chronic high blood pressure and/or aging, and may predict the progression of decline…
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