ATC Abstracts

American Transplant Congress abstracts

  • Home
  • Meetings Archive
    • 2020 American Transplant Congress
    • 2019 American Transplant Congress
    • 2018 American Transplant Congress
    • 2017 American Transplant Congress
    • 2016 American Transplant Congress
    • 2015 American Transplant Congress
    • 2013 American Transplant Congress
  • Keyword Index
  • Resources
    • 2016 Resources
      • 2016 Welcome Letter
      • ATC 2016 Program Planning Committees
      • ASTS Council 2015-2016
      • AST Board of Directors 2015-2016
    • 2015 Resources
      • 2015 Welcome Letter
      • ATC 2015 Program Planning Committees
      • ASTS Council 2014-2015
      • AST Board of Directors 2014-2015
      • 2015 Conference Schedule
  • Advanced Search

Results of Biopsies in Pancreas and Kidney-Pancreas Patients with Graft Dysfunction.

P. Uva, L. Leon, E. Minue, I. Cabrera, A. Giunippero, M. Norese, M. Toniolo, E. Chuluyan, D. Casadei.

Nephrology, Buenos Aires, Argentina.

Meeting: 2016 American Transplant Congress

Abstract number: A64

Keywords: Biopsy, Pancreas

Session Information

Date: Saturday, June 11, 2016

Session Name: Poster Session A: Clinical Pancreas Transplantation and All Islet Cell Transplantation Topics

Session Time: 5:30pm-7:30pm

 Presentation Time: 5:30pm-7:30pm

Location: Halls C&D

Related Abstracts
  • Which Place of Pancreas Graft Biopsy in the Management of Pancreas Transplant Recipients?
  • Low Level Pre-Transplant DSAs Are Frequent but Are Not Associated with a Rejection Diagnosis in Pancreas Transplant Biopsies

In pancreas transplantation there is no reliable laboratory test or imaging study for detection of graft rejection. There is an increasing interest in obtaining pancreas tissue for diagnosis of rejection, type and grade of rejection, evaluation of chronic damage, drug toxicity and recurrence. We describe our series of 83 “for cause” biopsies in pancreas and kidney-pancreas transplant patients over the past four years.

Methods: This is a retrospective review of a prospectively collected database. Only biopsies performed because of graft dysfunction were included from 1/2012 until 11/2015. Kidney dysfunction was defined as an unexplained raise in creatinine levels. Pancreas dysfunction was defined as elevated pancreatic enzymes or hyperglycemia. Most of our biopsies were performed laparoscopically.

Results: There were 45 biopsies for kidney dysfunction. 16 had kidney rejection, only 2 of them simultaneous pancreas rejection. Of the 29 without kidney rejection, there were 2 pancreas rejections. 12 patients were biopsied for both kidney and pancreas rejection. 6 patients had kidney rejection, and 5 of them had simultaneous pancreas rejection. Of the 6 patients without kidney rejection, there was 1 patient with pancreas rejection. Finally there were 26 patients biopsied for pancreas dysfunction. 5 were PTA cases and 2 of them had pancreas rejection. 8 patients had kidney rejection and 6 of them had simultaneous pancreas rejection. Of the 13 patients without kidney rejection, 6 had pancreas rejection.

Conclusion: Pancreas tissue is highly desirable in pancreas transplantation for kidney biopsy results are not reliable for pancreas diagnosis. We found a high incidence of asynchronous rejection in the three reasons for biopsy. We propose to perform both kidney and pancreas biopsies in the setting of graft dysfunction.

CITATION INFORMATION: Uva P, Leon L, Minue E, Cabrera I, Giunippero A, Norese M, Toniolo M, Chuluyan E, Casadei D. Results of Biopsies in Pancreas and Kidney-Pancreas Patients with Graft Dysfunction. Am J Transplant. 2016;16 (suppl 3).

  • Tweet
  • Email
  • Print

To cite this abstract in AMA style:

Uva P, Leon L, Minue E, Cabrera I, Giunippero A, Norese M, Toniolo M, Chuluyan E, Casadei D. Results of Biopsies in Pancreas and Kidney-Pancreas Patients with Graft Dysfunction. [abstract]. Am J Transplant. 2016; 16 (suppl 3). https://atcmeetingabstracts.com/abstract/results-of-biopsies-in-pancreas-and-kidney-pancreas-patients-with-graft-dysfunction/. Accessed February 28, 2021.

« Back to 2016 American Transplant Congress

Most Viewed Abstracts

  • This Week
  • This Month
  • All Time
  • A Decade of Donor-Derived Disease: A Report of the OPTN Ad Hoc Disease Transmission Advisory Committee (DTAC).
  • Low GFR after Kidney Donation Is Not Chronic Kidney Disease
  • Subtherapeutic Low Tacrolimus Trough Levels (≤3.5 Ng /ml) Are A Risk Factor For Acute Rejection And Creatinine Doubling.
  • Is There a Difference Between DCD and DBD Kidney Transplantation with Similar KDPI?
  • Kidney Dialysis after Heart Transplantation: The Short and Long Term Outcomes
  • Low GFR after Kidney Donation Is Not Chronic Kidney Disease
  • Subtherapeutic Low Tacrolimus Trough Levels (≤3.5 Ng /ml) Are A Risk Factor For Acute Rejection And Creatinine Doubling.
  • Penis Transplantation: First U.S. Experience.
  • A Decade of Donor-Derived Disease: A Report of the OPTN Ad Hoc Disease Transmission Advisory Committee (DTAC).
  • Is There a Difference Between DCD and DBD Kidney Transplantation with Similar KDPI?
  • Penis Transplantation: First U.S. Experience.
  • Is There a Difference Between DCD and DBD Kidney Transplantation with Similar KDPI?
  • Low GFR after Kidney Donation Is Not Chronic Kidney Disease
  • Evidence of a Clinically Significant Drug-Drug Interaction between Cannabidiol and Tacrolimus: A Case Report
  • Kidney Dialysis after Heart Transplantation: The Short and Long Term Outcomes

Visit Our Partner Sites

American Transplant Congress (ATC)

Visit the official site for the American Transplant Congress »

American Journal of Transplantation

The official publication for the American Society of Transplantation (AST) and the American Society of Transplant Surgeons (ASTS) »

American Society of Transplantation (AST)

An organization of more than 3000 professionals dedicated to advancing the field of transplantation. »

American Society of Transplant Surgeons (ASTS)

The society represents approximately 1,800 professionals dedicated to excellence in transplantation surgery. »

Copyright © 2013-2021 by American Society of Transplantation and the American Society of Transplant Surgeons. All rights reserved.

Privacy Policy

loading Cancel
Post was not sent - check your email addresses!
Email check failed, please try again
Sorry, your blog cannot share posts by email.
This site uses cookies: Find out more.