ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Biopsy"

  • 2017 American Transplant Congress

    Importance of HLA-DR Expression in Pediatric Renal Transplant Biopsies.

    O. Moussa, S. Self, K. Twombley.

    Medical University of South Carolina, Charleston

    ObjectiveTo determine which types of injuries in pediatric kidney transplant patients were associated with HLA-DR expression.Design/MethodsA retrospective chart review was conducted of children receiving a…
  • 2017 American Transplant Congress

    Molecular Analysis of Acute Rejection in Formalin-Fixed Paraffin-Embedded Clinical Face Transplant Biopsies.

    T. Win,1 B. Dyring-Andersen,1 V. Barrera,2 S. Ho Sui,2 R. Lopdrup,1 H. Kiwanuka,1 N. Murakami,1 J. Teague,1 E. Lowry,1 E. Bueno,1 A. Chandraker,1 L. Riella,1 B. Pomahac,1 R. Clark.1

    1Brigham and Women's Hospital, Boston, MA; 2Harvard T.H. Chan School of Publich Health, Boston

    BackgroundDiagnosis of acute rejection in face transplants relies on the histological evaluation of allograft skin biopsies using BANFF classification, an approach with significant limitations including…
  • 2017 American Transplant Congress

    Development of Transplant Glomerulopathy in Recipients with Antibody Mediated Rejection: Activation of Inflammatory Pathway Through Renal Poly (ADP-Ribose) Polymerase (PARP).

    B. Ozdemir,1 F. Ozdemir,2 E. Baskin,2 M. Haberal.3

    1Pathology, Baskent University, Ankara, Turkey; 2Pediatric Nephrology, Baskent University, Ankara, Turkey; 3Transplant Surgery, Baskent University, Ankara, Turkey

    Activation of PARP is a critical factor in the pathogenesis of various inflammatory and fibrotic process. Thus we aimed to show the integral of PARP…
  • 2017 American Transplant Congress

    Outcomes for Plasma Cell Rich Rejection in Pediatric Kidney Transplant Patients.

    O. Moussa, S. Self, K. Twombley.

    Medical University of South Carolina, Charleston

    Introduction and Objective:Plasma cell rich rejection (PCR) has historically been associated with poor outcomes, but there has been minimal data published to date on pediatric…
  • 2016 American Transplant Congress

    Long-Term Death-Censored Graft Loss in the DeKAF Study.

    A. Matas,1 A. Fieberg,1 R. Leduc,1 F. Cosio,2 R. Gaston,3 R. Mannon,3 M. Cecka,4 D. Rush,7 B. Kasiske,5 S. Gourishankar,6 J. Connett,1 J. Grande.2

    1U of MN, Mpls, MN; 2Mayo, Rochester, MN; 3UAB, Birmingham, AB; 4UCLA, LA, CA; 5HCMC, Mpls, MN; 6U Alberta, Edmonton, AB, Canada; 7UMB, Winnipeg, MB, Canada.

    The aim of the Deterioration of Kidney Allograft Function study (DeKAF) was to identify and assess the pathologies of troubled kidney grafts, that is, those…
  • 2016 American Transplant Congress

    Urinary Exosomal Annexin A1 Is a Predictive Biomarker of Post Kidney Transplant Complications.

    H. Harada,1 T. Murakami,2 C. Yamamoto,2 K. Hotta,1 N. Fukuzawa,1 M. Mitsuhashi.2

    1Kidney Transplant Surgery, Sapporo City General Hospital, Sapporo, Japan; 2Hitachi Chemical Co. America, Ltd., Irvine, CA; 3Nanosomix, Inc., Aliso Viejo, CA.

    IntroductionMonitoring of kidney allograft condition is important. We had exhibited non-invasive diagnostic modality of post-kidney transplant complications using urine exosomal and microvesicule (EMV) mRNA of…
  • 2016 American Transplant Congress

    Characterization of Vascular Lesions in Living Donor Renal Transplant Implant Biopsies.

    F. Tinney Jr,1 L. Yessayan,2 M. Abouljoud,3 A. Patel.3

    1Wayne State University School of Medicine, Detroit, MI; 2Department of Nephrology, Henry Ford Hospital, Detroit, MI; 3Transplant Institute, Henry Ford Hospital, Detroit, MI.

    INTRODUCTION: Nephrosclerosis is often associated with pathological injury to kidneys resulting from chronic high blood pressure and/or aging, and may predict the progression of decline…
  • 2016 American Transplant Congress

    A Molecular Biopsy Test for Probability of Non-Adherence.

    P. Halloran,1,3 G. Einecke,2 J. Reeve.1

    1ATAGC, Edmonton, AB, Canada; 2Hannover Medical School, Hannover, Germany; 3Department of Medicine, University of Alberta, Edmonton, AB, Canada.

    Afferent arteriolar hyalinosis (ah-score) in renal transplant biopsies increases with time of biopsy-post-transplant (TxBx), reflecting calcineurin inhibitor drug effects, donor aging, and progressive glomerular diseases.…
  • 2016 American Transplant Congress

    A Quantitative CD45 Immunohistochemical Assay Allows Precise and Reproducible Measurement of Inflammation in Renal Transplant Biopsies.

    V. Walavalkar,1 S. Bowman,1 L. Laszik,1 D. Ikle,2 S. Chandran,1 F. Vincenti,1 Z. Laszik.1

    1UCSF, San Francisco, CA; 2Rho, Chapel Hill, NC.

    Purpose: Total inflammation (TI) is an important variable for the pathologic work-up of transplant kidney biopsies (TxBx) in the Banff schema. However, current standard pathologic…
  • 2016 American Transplant Congress

    Clinical Outcomes of Kidney Allograft Recipients with Apolipoprotein L1 (APOL1) Risk Alleles from Living Kidney Donors.

    C. Dorr,1,2,3 A. Hart,1,2,3 D. Schladt,1 A. Muthusamy,1 R. Mannon,4 W. Oetting,2 A. Matas,2 P. Jacobson,2 A. Israni.1,2,3

    1Minneapolis Medical Research Foundation, Minneapolis; 2University of Minnesota, Minneapolis; 3Hennepin County Medical Center, Minneapolis; 4University of Alabama, Birmingham.

    Background:Apolipoprotein L1 (APOL1) alleles G1 and G2 in deceased donors are associated with poor kidney allograft survival. However, the effect of these alleles in living…
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