2017 American Transplant Congress
Human Transitional B Cell Cytokine Profile Predicts Renal Allograft Rejection and Clinical Course.
In Kidney Transplant Recipients (KTRs), non-invasive predictive biomarkers that allow early intervention are limited. Here we report findings from a prospective longitudinal study using B…2017 American Transplant Congress
The Immunophenotype of Peritubular Capillaritis in Renal Transplant Biopsies.
Background: Peritubular capillaritis (ptc) is a feature of acute antibody-mediated rejection (ABMR) in the renal allograft. However, it is not an specific feature for ABMR…2017 American Transplant Congress
Quantitative Gene Expression Analysis of CRM-Panel Genes Using FFPE Kidney Tissues for Transplant Injuries.
University of California San Francisco, San Francisco
Background: A common immune response module (CRM) of 11 genes was identified to define acute rejection (AR) through meta-analyses of 1030 different engrafted tissues including…2017 American Transplant Congress
Integrated Magnetic-Electrochemical Exosome (iMEX) Technology to Detect Rejection in Kidney Transplant Recipients.
Transplantation Research Center, Harvard Medical School, Boston; Exosome Diagnostic Inc, Cambridge
Methods for monitoring clinical rejection including increases in serum creatinine and urinary protein excretion may not reflect subclinical rejection. Similarly repeat biopsy may result in…2016 American Transplant Congress
Standardized Pre-Implantation Kidney Biopsies of Expanded Criteria Donors to Improve the Kidney Donor Profile Index (KDPI) for the Evaluation of Marginal Donors.
There is no consensus of selection criteria used to allocate renal transplants from expanded criteria donors (ECD). The Kidney Donor Profile Index (KDPI) has been…2016 American Transplant Congress
Chronic Infection by Hepatitis C Virus and the Development of Transplant Glomerulopathy.
OBJETIVE: To demonstrate that chronic infection with the hepatitis C virus (HCV) is a risk factor for the development of transplant glomerulopathy in a large…2016 American Transplant Congress
Predictors of Early Rejection and Allograft Failure in Pediatric Kidney Transplantation: Impact of Histology and Behavior.
University of Alabama at Birmingham School of Medicine, Birmingham.
Background: Early inflammatory events that lead to allograft dysfunction are often missed by creatinine-based estimates in children. Surveillance biopsies can detect early allograft dysfunction due…2016 American Transplant Congress
Mapping Heterogeneity in Antibody-Mediated Rejection Using Molecular Phenotypes and Archetype Analysis.
Archetype analysis is a method for identifying new relationships among samples without subdividing them into classes, finding a limited number of archetypical cases and calculating…2016 American Transplant Congress
Interaction Between Kidney Tissue Proteome and Humoral Immunity in Antibody Mediated Rejection.
PURPOSE: Antibody-mediated rejection (AMR) is caused by antibodies against human leukocyte antigens (HLA) on graft endothelium, and non-HLA antibodies that target endothelial and epithelial proteins.…2016 American Transplant Congress
Role of Natural Killer Cells in Kidney Transplant Outcome.
Aim of the study was to evaluate the relationship between killer cell immunoglobulin-like receptor (KIR) phenotype and kidney transplant rejection. NK-target cell interaction depends on…
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