ATC Abstracts

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Articles tagged "Biopsy"

  • 2017 American Transplant Congress

    Transcriptomic Analysis Revealed a Fibrotic Role of Epithelial Cells Originated from the Recipient in Kidney Transplant.

    W. Zhang,1 Z. Yi,1 E. Stahl,2 M. Menon,1 K. Keung,3 K. Hao,2 P. O'Connell,3 B. Murphy.1

    1Medicine, Icahn School of Medicine at Mount Sinai, New York, NY; 2Department of Genetics and Genomic Science, Ichan School of Medicine at Mount Sinai, New York, NY; 3Renal Unit, University of Sydney at Westmead Hospital, Sydney, Australia

    Renal fibrosis is one of major causes for chronic renal dysfunction in kidney diseases and graft loss in kidney transplant. With an aim to better…
  • 2017 American Transplant Congress

    Persistence/Progression of Early Banff Borderline Changes (BBC) Is Associated with Chronic Renal Allograft Damage and Can Be Predicted by B Cell Cytokine Profile.

    A. Cherukuri, A. Sharma, R. Mehta, S. Hariharan, D. Rothstein.

    UPMC, Pittsburgh

    The clinical significance of early histological BBC in kidney transplant recipients (KTR) is unclear. It is also unknown if biomarkers predict progression to acute rejection…
  • 2017 American Transplant Congress

    Does Histologic Grade in BK Polyoma Nephropathy Associate with Viral Load, Allograft Dysfunction or Allograft Loss? A Single Center Experience.

    M. Swee,1 S. Kuppachi,1 M. Fraer,1 P. Rastogi,2 P. Ten Eyck,1 M. Sanders.1

    1Nephrology, University of Iowa, Iowa City, IA; 2Pathology, University of Iowa, Iowa City, IA

    Purpose: BK polyoma nephropathy (BKPyN) is a well-recognized cause of allograft dysfunction and loss after kidney transplant. Despite increased recognition, it is unclear if changes…
  • 2017 American Transplant Congress

    Impact of Six-Month Surveillance Biopsies and Monitoring in Pediatric Renal Transplant Recipients.

    J. Lyons,1,2,3 D. Ranch,1,2 R. Hall,1,2,3 P. Maxwell,1,2,3 K. Hitchman,1,2 Y. Hirase,3 B. Crowther.1,2,3

    1University Health System, San Antonio, TX; 2University of Texas Health Science Center San Antonio, San Antonio, TX; 3University of Texas College of Pharmacy, Austin, TX

    Purpose: Evaluate the utility of surveillance biopsies and monitoring 6 months post-transplant.Methods: A retrospective single center chart review of pediatric renal transplant recipients from 01/2011–10/2015…
  • 2016 American Transplant Congress

    Criteria for the Diagnosis of Microvascular Inflammation (MVI) in Kidney Transplant Biopsies (KTxBx).

    J. Grande,1 R. Leduc,2 The DeKAF Study Group.

    1Dept. of Lab Medicine & Pathology, Mayo Clinic College of Medicine, Rochester, MN; 2Division of Biostatistics, U. Minnesota School of Public Health, Minneapolis, MN.

    The presence of MVI (Banff glomerulitis "g" score and Banff peritubular capillary "ptc" score) in KTxBx, often related to antibody mediated rejection (AMR), is associated…
  • 2016 American Transplant Congress

    Results of Biopsies in Pancreas and Kidney-Pancreas Patients with Graft Dysfunction.

    P. Uva, L. Leon, E. Minue, I. Cabrera, A. Giunippero, M. Norese, M. Toniolo, E. Chuluyan, D. Casadei.

    Nephrology, Buenos Aires, Argentina.

    In pancreas transplantation there is no reliable laboratory test or imaging study for detection of graft rejection. There is an increasing interest in obtaining pancreas…
  • 2016 American Transplant Congress

    Management and Outcomes of Upper Extremity Deep Venous Thrombosis in Heart Transplant Patients.

    A. Panakos,1 D. Kramer,1 M. McCarey,1 P. Mather.2

    1Internal Medicine, Thomas Jefferson University Hospital, Philadelphia, PA; 2Cardiology, Thomas Jefferson University Hospital, Philadelphia, PA.

    Upper extremity deep venous thrombosis (UEDVT) is common in post-heart transplant (OHT) patients, likely due to their multiple intravascular catheters and post-surgical state. The clinical…
  • 2016 American Transplant Congress

    Comparison of C4d Deposition in Renal Biopsies with Luminex-Based C3d Single Antigen Bead (SAB) Detection.

    R. Pelletier,1 I. Balazs,2 P. Adams,3 P. Steller,3 N. DiPaola,4 L. Rankin,3 A. Diez,5 M. Henry.1

    1Surgery/Transplant, The Ohio State University Wexner Medical Center, Columbus, OH; 2Discovery Research, Immucor, Inc, Stamford, CT; 3Tissue Typing, The Ohio State University Wexner Medical Center, Columbus, OH; 4Methodist Hospital, Houston, TX; 5Nephrology, The Ohio State University Wexner Medical Center, Columbus, OH.

    Recent interest in characterizing the complement-fixing ability of post-transplant donor specific alloantibodies (DSA) resulted in the enhancement of luminex solid phase alloantibody assays to determine…
  • 2016 American Transplant Congress

    Age-Based High GFR Associates with Clinical Risk Among Potential Living Donors, but Only with Increased Nephron Number Among Approved Donors.

    H. Chakkera,1 E. Poggio,3 A. Denic,2 J. Mathew,2 W. Kremers,2 J. Larson,2 H. Amer,2 F. Cosio,2 M. Stegall,2 S. Taler,2 A. Rule.2

    1Mayo Clinic, Arizona; 2Mayo Clinic, Rochester; 3Cleveland Clinic, OH.

    Background:Association of high GFR with clinical and kidney structural characteristics among living donors has not been studied.Methods: Study cohort:potential kidney donors evaluated at Mayo Clinic…
  • 2016 American Transplant Congress

    Glomerular Capillary C4d Staining without Evidence of Rejection Is Associated with Worse Graft Function in ABO-Incompatible Kidney Transplantation.

    D. Toki,1 M. Inui,1 M. Okumi,2 H. Ishida,2 K. Setoguchi,1 T. Shimizu,2 K. Unagami,2 K. Tanabe.2

    1Urology, Tokyo Women's Medical University Yachiyo Medical Center, Chiba, Japan; 2Urology, Tokyo Women's Medical University, Tokyo, Japan.

    Objectives: C4d staining in the peritubular capillaries (C4d-PTC) is often observed without evidence of rejection in ABO-incompatible kidney transplantation (ABOI-KTx), and this phenomenon is generally…
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