ATC Abstracts

American Transplant Congress abstracts

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  • 2021 American Transplant Congress

    Distinct Phenotype and Function of Antibody-suppressor Cxcr5+Cd8+ T Cells

    J. Zimmerer, J. Han, M. Hart, S. Chaudhari, C. Peterson, G. Bumgardner

    OSU, Columbus, OH

    *Purpose: We have reported that the novel subset of antibody-suppressor CD8+ T cells (termed CD8+ TAb-supp cells) require the expression of CXCR5. In addition, alloprimed…
  • 2021 American Transplant Congress

    LacripepTM-like Peptide N-104 Increases Insulin Secretion and Promotes Islet Transplantation Outcomes

    M. Ma, P. Chhabra, K. Dias Teixeira, G. Laurie, K. Brayman

    University of Virginia Health System, Charlottesville, VA

    *Purpose: To study if LacripepTM-like peptide N-104 promotes beta-cell stabilization and islet transplantation outcomes. Background: Lacritin is a multifunctional tear protein with prosecretory, prosurvival and…
  • 2021 American Transplant Congress

    Sigma-1 Receptor Agonists are Renoprotective in Experimental Kidney Transplantation

    A. Hosszu1, T. Lakat1, A. Toth1, D. Balogh1, J. Hodrea1, L. J. Wagner2, A. J. Szabo1, A. Fekete1

    11st Department of Pediatrics, Semmelweis University, Budapest, Hungary, 2Department of Transplantation and Surgery, Semmelweis University, Budapest, Hungary

    *Purpose: Kidney transplantation (Tx) is associated with better quality of life and reduced costs compared to dialysis, but the shortage in donor organs is a…
  • 2021 American Transplant Congress

    Characterization of Kidney Small Extracellular Vesicles Released During Normothermic Machine Perfusion

    W. W. Woud1, A. Arykbaeva2, D. de Vries2, I. Alwayn2, K. Boer1, C. Baan1, M. Hoogduijn1, R. Minnee3

    1Internal Medicine, Nephorology and Transplantation, Erasmus MC, Rotterdam, Netherlands, 2Department of Surgery, LUMC, Leiden, Netherlands, 3Department of Surgery, Division of Hepato-Pancreato-Biliary and Transplant Surgery, Erasmus MC, Rotterdam, Netherlands

    *Purpose: By characterizing and quantifying the dynamical release of kidney Extracellular Vesicles (EVs) during Normothermic Machine Perfusion (NMP), we aim to gain a better understanding…
  • 2021 American Transplant Congress

    Longitudinal Surveillance, Relative Change Value (RCV) Improve Diagnostic Test Accuracy (DTA) of Donor-Derived Cell Free DNA (dd-cfDNA)

    S. Anand, F. Lopez-Verdugo, J. Sanchez-Garcia, L. Dong, M. Fife, J. Krong, D. Morris, T. Srinivas

    Intermountain Medical Center, Murray, UT

    *Purpose: dd-cfDNA, an injury biomarker in kidney transplant (KTx), is emerging as a trigger for biopsy (Bx) and superior to the traditional trigger of change…
  • 2021 American Transplant Congress

    Characteristics, Risk Factors, and Outcomes of Neutropenia for the First Year After Liver or Kidney Transplantation in Children

    C. Jarasvaraparn1, S. Choudhury2, C. Rusch2, K. Liss1, J. Stoll1, S. Hmiel3, S. Kulkarni1

    1Pediatric Gastroenterology, Washington University School in St Louis, Saint Louis, MO, 2Pediatric, Washington University School in St Louis, Saint Louis, MO, 3Pediatric Nephrology, Washington University School in St Louis, Saint Louis, MO

    *Purpose: Prior studies in adults have shown that approximately 20-38 % of subjects undergoing solid organ transplant develop neutropenia. In the current study, we characterized…
  • 2021 American Transplant Congress

    Immunosuppression Impacts Panel Reactive Antibody Status in Second Solid Organ Transplant Recipients – A Single Center Experience

    J. Patel1, S. Ali2, M. L. Sanders1, C. P. Thomas1, D. Axelrod1, M. Bilal3, E. H. Field3, S. Kuppachi1

    1University of Iowa Hospitals & Clinics, Iowa city, IA, 2Louis A. Johnson VA Medical Center, Clarksburg, WV, 3Iowa City VA Health Care System, Iowa city, IA

    *Purpose: Patients who require a second solid organ transplantation are significantly disadvantaged due to the event of sensitization due to the first transplant. We hypothesized…
  • 2021 American Transplant Congress

    Evaluation of Serum Klotho Levels at Early Kidney Post-Transplant

    T. Vazquez-Sanchez1, J. Alonso-Titos1, M. Sánchez-Niño2, E. Sola1, M. Leon3, V. Lopez1, P. Ruiz-Esteban1, E. Porrini4, A. Ortiz5, D. Hernández1

    1Nephrology, Instituto de Investigación Biomédica de Málaga (IBIMA). Hospital Universitario Regional de Málaga and University of Málaga. REDinREN (RD16/0009/0006). Málaga. (Spain), Malaga, Spain, 2Nephrology, Instituto de InvestigaciónSanitaria de la FundaciónJiménez Díaz,UniversidadAutónoma de Madrid. REDINREN, Madrid, Spain, 3Pathology, Instituto de Investigación Biomédica de Málaga (IBIMA). Hospital Universitario Regional de Málaga and University of Málaga. REDinREN (RD16/0009/0006). Málaga. (Spain), Malaga, Spain, 4Nephrology, Hospital Universitario de Canarias, CIBICAN, Universidadde laLaguna, REDinREN (RD16/0009/0031) Tenerife e Instituto Reina Sofía de Investigación Renal (IRSIN), Malaga, Spain, 5Nephrology, Instituto de InvestigaciónSanitaria de la FundaciónJiménez Díaz,UniversidadAutónoma de Madrid. REDINREN, Malaga, Spain

    *Purpose: Klotho expression is lowered in patients with chronic kidney disease (CKD). After kidney transplant (KT), serum Klotho levels could be significantly increased compared to…
  • 2021 American Transplant Congress

    Development of a Question Prompt Sheet for Upper Extremity Vascularized Composite Allotransplantation

    J. Gacki-Smith1, B. Kuramitsu1, A. Ferzola2, K. Vanterpool2, C. Kunkle3, M. Hewitt3, A. Schultheis3, T. Riggleman3, J. Taylor3, C. Cooney2, M. Levan2, S. Tintle3, G. Brandacher2, E. Gordon1

    1Northwestern University, Chicago, IL, 2Johns Hopkins University, Baltimore, MD, 3Walter Reed National Military Medical Center, Bethesda, MD

    *Purpose: Upper extremity (UE) vascularized composite allotransplantation (VCA) is an innovative option for people with UE amputations. Individuals with limb loss commonly receive little information…
  • 2021 American Transplant Congress

    Impact of Donor and Recipient Age Difference: Outcomes within the First Year of Orthotopic Heart Transplant

    M. Mascetti, M. Manson, Z. Truman

    Baylor St. Luke's Medical Center, Houston, TX

    *Purpose: In recent history, the number of patients listed as eligible to receive a heart transplant has increased by nearly 40%. However, not all hearts…
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