2021 American Transplant Congress
Transplant Glomerulopathy in the Absence of Donor-specific HLA Antibodies: Risk Factors, Histopathological Features and Graft Outcome
Microbiology, Immunology and Transplantation, KU Leuven, Leuven, Belgium
*Purpose: Transplant glomerulopathy (TG) is established as a hallmark of chronic antibody-mediated rejection in kidney transplant patients with donor-specific HLA antibodies (HLA-DSA). The clinical importance…2021 American Transplant Congress
The Predictive Factors of Survival in Re-listed Patients Who Received Initial Liver Transplants Using Donation After Circulatory Death Grafts
Cleveland Clinic, Cleveland, OH
*Purpose: The inherent risk of livers from donors after circulatory death (DCD) is well known such as primary non-function (PNF) and increased rates of biliary…2021 American Transplant Congress
Neutrophil Extracellular Trap-induced Thrombotic Microangiopathy in Steatotic Mouse Recipients Impacts Liver Transplant Outcomes
UCLA Medical Center, Los Angeles, CA
*Purpose: Nonalcoholic steatohepatitis (NASH) is an emerging global epidemic projected to become the leading indication for liver transplantation (LT). Although recent studies focus on the…2021 American Transplant Congress
The Risk of Post-donation Kidney Function Impairment for Prospective Living Kidney Donors with Persistent Isolated Microscopic Hematuria
*Purpose: According to current guidelines, a kidney biopsy is indicated in prospective living kidney donors who present with persistent isolated microscopic hematuria (PIMH) during evaluation,…2021 American Transplant Congress
The Use of Hcv Nat+ Organs in Hcv Negative Recipients with On-site Specialty Pharmacy Services: A Win for the Patient, the Transplant Center, and Society?
Medical University of South Carolina, Charleston, SC
*Purpose: Use of HCV AB positive organs (HCV AB+) with active viremia (NAT+) relies on appropriate and timely use of direct acting antiviral therapies (DAA).…2021 American Transplant Congress
Selective Regulatory T Cell Expansion by a Novel IL-2 Mutein Prolongs Skin Transplant Survival in Mice
*Purpose: Long-term immunosuppression predisposes transplant patients to a greater risk of infection, malignancy and kidney toxicity. Hence, alternative methods to regulate the immune system are…2021 American Transplant Congress
Impact of SARS-CoV 2 Infection on Graft Function in Kidney Transplant Recipients: An Academic Single Center Experience
Northwestern University, Chicago, IL
*Purpose: Kidney transplant recipients are a unique cohort in regard to SARS-CoV 2 susceptibility and clinical course, owing to their immunosuppressed state and propensity for…2021 American Transplant Congress
Creating Efficiency in the Kidney Transplant Listing: Can We Streamline Candidate Ineligibility?
Tulane Abdominal Transplant Institute, New Orleans, LA
*Purpose: Evaluation of multiple transplant candidate referrals is a resource-intensive process that may delay listing and eventually transplanting appropriate patients. In this study, we sought…2021 American Transplant Congress
Inhibition of Fatty Acid Beta-Oxidation Prolongs Heart Allograft Survival
Surgery, Washington University School of Medicine, Saint Louis, MO
*Purpose: To test the therapeutic efficacy of pharmacological inhibition of fatty acid beta-oxidation (FAO) on acute heart allograft survival.*Methods: We used a heterotopic Balb/c donor…2021 American Transplant Congress
Development of a Rat Model of Antibody-Mediated Rejection After Liver Transplantation
*Purpose: Antibody-mediated rejection (AMR) is a refractory rejection after donor-specific antibody (DSA)-positive or ABO blood-type incompatible liver transplantation (LT), due at least in part to…
American Transplant Congress abstracts