ATC Abstracts

American Transplant Congress abstracts

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  • 2016 American Transplant Congress

    Prostate Cancer Characteristics and Outcome in Renal Transplant Recipients: Results from a Contemporary Monocentric Study.

    C. Pettenati,1 A.-S. Jannot,2 V. Verkarre,3 S. Hurel,1 H. Kreis,4 M. Housset,5 C. Legendre,4 A. Méjean,1 M.-O. Timsit.1

    1Department of Urology and Transplant surgery, Hôpital Européen Georges Pompidou, AP-HP, Université Paris Descartes, Paris, France; 2Department of Statistics, Computing and Public Health, Hôpital Européen Georges Pompidou, AP-HP, Université Paris Descartes, Paris, France; 3Department of Pathology, Hôpital Necker, AP-HP, Université Paris Descartes, Paris, France; 4Department of Nephrology and Transplantation, Hôpital Necker, AP-HP, Université Paris Descartes, Paris, France; 5Department of Onco-Radiotherapy, Hôpital Necker, AP-HP, Université Paris Descartes, Paris, France.

    Objective To analyze prostate cancer characteristics in a contemporary monocentric renal transplant recipients (RTR) population and to compare oncological outcome after radical prostatectomy (RP) with…
  • 2016 American Transplant Congress

    Anti-Thymocyte Globulin Induced Thrombocytopenia and Bleeding After Kidney Transplantation.

    M. Dokus,1 A. Patel,1 J. Iuppa,2 E. Venniro,3 A. Danzig,1 J. Cooley,2 J. Taylor,3 R. Kashyap,1 M. Orloff.1

    1Department of Surgery, Division of Transplant and Hepatobiliary Surgery, University of Rochester, Rochester, NY; 2Department of Pharmacy, University of Rochester, Rochester, NY; 3Department of Medicine, Division of Nephrology, University of Rochester, Rochester, NY.

    Background: Bleeding is a significant challenge after renal transplantation. Anti-thymocyte globulin (ATG) induced thrombocytopenia may increase bleeding after kidney transplantation (KTx), but this association has…
  • 2016 American Transplant Congress

    Evaluation of Long Term Outcome After Living Donor Liver Transplantation in Sequential 653 Recipients with or without Viral Infection: Is HBV & HCV Co-Infection Better Than the Monoinfection? A Single Center Retrospective Analysis.

    H. Yang, A. Thorat, L. Jeng, C.-C. Yeh, T.-H. Chen, S.-C. Hsu, K.-S. Poon.

    Organ Transplantation, China Medical University Hospital, Taichung, Taiwan.

    Background:End-stage liver disease secondary to HBV and HCV coinfection is not uncommon in Asia.However,long term outcome of such patients after living donor liver transplantation (LDLT)…
  • 2016 American Transplant Congress

    Accepted Mouse Kidney Allografts Are Characterized by Widespread Nitrosylation.

    I. Aljabban, B. Jiang, C. Yang, D. Ndishabandi, R. White, P. Russell, J. Madsen, R. Colvin, A. Alessandrini.

    Center for Transplantation Sciences, Dept. of Surgery, Dept. of Pathology, Massachusetts General Hospital, Boston, MA.

    Leukocytes can modulate the immune response through manipulation of amino acid metabolism. Research indicates that depletion of L-arginine and generation of nitric oxide (NO) suppresses…
  • 2016 American Transplant Congress

    The Impact of Sequential Gene Modifications on Cardiac Xenograft Survival.

    K. Horvath,1 A. Singh,1 J. Chan,1 M. Thomas,2 B. Lewis,2 D. Ayares,3 P. Corcoran,1 M. Mohiuddin.1

    1CSRP, NHLBI/NIH, Bethesda, MD; 2DVR / ORS, NIH, Bethesda, MD; 3Revivicor, Inc, Blacksburg, VA.

    Introduction: One of the major advances in xenotransplantation is the ability to modify donor pig genetics. Using rapidly evolving techniques of pig cloning and gene…
  • 2016 American Transplant Congress

    IL-17-Producing CCR6+CD4+ Th17 Cells Drive Intestinal Allograft Rejection in Humans.

    J. Kaiser, C. Cosentino, A. Shukla, C. Desai, R. Girlanda, J. Hawksworth, C. Matsumoto, M. Zasloff, T. Fishbein, A. Kroemer.

    MedStar Georgetown Transplant Institute, Washington DC.

    A. Allograft rejection remains a significant source of mortality and morbidity in intestinal transplant (ITx) recipients. However, the underlying mechanisms remain unclear. The purpose of…
  • 2016 American Transplant Congress

    Outcomes of Solid Organ Transplant Recipients with Pre-Existing Malignancies.

    S. Acuna,1,2,3 R. Sutradhar,1,2 J. Kim,1,2,4 N. Baxter.1,2,3

    1Institute of Health Policy, Management and Education, University of Toronto, Toronto, ON, Canada; 2Institute of Clinical Evaluative Sciences, Toronto, ON, Canada; 3Department of Surgery, St. Michael's Hospital, Toronto, ON, Canada; 4Department of Medicine, University Health Network, Toronto, ON, Canada.

    Background: Pre-transplant malignancy (PTM) is considered a relative contraindication for transplantation due to the heightened risk of cancer recurrence associated with immunosuppression. However, little has…
  • 2016 American Transplant Congress

    Live Donor Liver Transplantation for NASH: The Toronto Experience.

    A. Barbas, N. Goldaracena, M. Dib, M. Marquez, G. Sapisochin, D. Al-Adra, I. McGilvray, M. Cattral, P. Greig, D. Grant.

    General Surgery, Multi-Organ Transplant, University of Toronto, Toronto, ON, Canada.

    Background:Non-alcoholic steatohepatitis (NASH) is an increasingly common indication for liver transplantation in North America. In the context of organ scarcity and significant waitlist mortality, our…
  • 2016 American Transplant Congress

    BK Nephropathy, but Not Isolated BK Viremia Associated with De Novo DSA Despite Similar Immunosuppression Reduction.

    W. Cheungpasitporn,1 D. Mitema,1 H. Amer,1 F. Cosio,1 M. Stegall,2 C. Schinstock.1

    1Nephrology and Hypertension, Mayo Clinic, Rochester, MN; 2Transplantation Surgery, Mayo Clinic, Rochester, MN.

    Introduction: Reduced immunosuppression is associated with de novo DSA (dn DSA). Although immunosuppression is often reduced in patients with polyomavirus (BK), the incidence of dn…
  • 2016 American Transplant Congress

    Acute Kidney Injury and Chronic Kidney Disease in Donation After Circulatory Death Liver Transplantation: UK Single Centre Study.

    I. Umbro,1,2 F. Tinti,1,2 F. Evison,3 A. Sharif,4 B. Gunson,5 A. Mitterhofer,2 J. Ferguson,1 P. Muiesan.1

    1The Liver Unit, Queen Elizabeth Hospital, Birmingham, United Kingdom; 2Nephrology and Dialysis Unit, Sapienza University of Rome, Rome, Italy; 3Department of Health Informatics, University Hospitals Birmingham NHS Foundation Trust, Birmingham, United Kingdom; 4Department of Nephrology and Transplantation, Queen Elizabeth Hospital, Birmingham, United Kingdom; 5NIHR Birmingham Liver Biomedical Research Unit and Centre for Liver Research, University of Birmingham, Birmingham, United Kingdom.

    Aim of the study is to assess the incidence of acute kidney injury (AKI) and chronic kidney disease (CKD) after liver transplantation (LT) in DCD…
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