Am J Transplant, Volume 16, Suppl 3 Archives - ATC Abstracts

2016 American Transplant Congress
Diffuse Extent of Peritubular Capillaritis in Late Antibody Mediated Rejection Is Associated with More Severe Chronic Allograft Damage.
Z. Kikić,¹ F. Eskandary,¹ H. Herkner,² R. Oberbauer,¹ G. Bond,¹ H. Regele,³ G. Böhmig,¹ N. Kozakowski.³
¹Nephrology and Dialysis, Medical University of Vienna, Vienna, Austria; ²Emergency Medicine, Medical University of Vienna, Vienna, Austria; ³Institute of Clinical Pathology, Medical University of Vienna, Vienna, Austria.
Peritubular capillaritis (ptc) is a widely accepted histologic criterion of antibody-mediated rejection (ABMR), and while the ptc score is incorporated in current diagnostic recommendations, the…
2016 American Transplant Congress
iNKT Cell Ligands Administered with Bone Marrow Cells Expand Allo-Specific Regulatory T Cells In Vivo and Establish Transplant Tolerance.
S. Miyairi,^1,2 T. Hirai,¹ M. Okumi,¹ Y. Ishii,³ K. Yamazaki,² K. Tanabe.¹
¹Urology, Tokyo Women's Medical University, Tokyo, Japan; ²Cardiovascular Surgery, Tokyo Women's Medical University, Tokyo, Japan; ³Vaccine Design, RIKEN IMS-RCAI, Yokohama, Japan.
Invariant natural killer T(iNKT) cells have the powerful potential to expand regulatory T cells(Tregs), especially when they are presented α-galactosylceramide(aGC) by B cells. We previously…
2016 American Transplant Congress
A Novel Microfluidic Device for Purification of Pancreatic Islet Preparations.
W. Varhue,¹ L. Langman,² D. Bowers,³ S. Peirce-Cottler,³ N. Swami,¹ K. Brayman.²
¹Electrical and Computer Engineering, University of Virginia, Charlottesville, VA; ²Surgery, University of Virginia, Charlottesville, VA; ³Biomedical Engineering, University of Virginia, Charlottesville, VA.
Purpose: Demonstrate that novel continuous flow microfluidic designs can be utilized to remove contaminating acinar tissue and sort the purified islets, based on size and…
2016 American Transplant Congress
Thrombalexin: Detection & Efficacy of a Membrane-Bound Anti-Thrombin Agent.
M. Manook,^1,2 J. Kwun,¹ J. Yoon,¹ S. Sacks,² A. Dorling,² N. Mamode,² R. Smith,² S. Knechtle.¹
¹Surgery, Duke University, Durham; ²King's College, London, United Kingdom.
Introduction: Early activation of coagulation may be an important factor in the initiation of innate immunity. Anti-coagulation in the transplant setting is difficult due to…
2016 American Transplant Congress
In Vivo and In Vitro Characterization of 1.5 mm Ba²⁺-Alginate Macro-Encapsulated Cynomolgus Monkey Islets.
M. Bochenek,¹ J. McGarrigle,¹ J. Mendoza-Elias,¹ E. Marchese,¹ M. Nourmohammadzadeh,¹ Y. Wang,¹ A. Khan,¹ M. Omami,¹ C.-C. Yeh,¹ I. Lacik,² B. Strand,³ J. Oberholzer.¹
¹Transplant Surgery, University of Iliinois at Chicago, Chicago, IL; ²Biomaterials Research, Polymer Institute of the Slovak Academy of Sciences, Bratislava, Slovakia (Slovak Republic); ³Biotechnology, Norwegian University of Science and Technology, Trondheim, Norway.
Introduction:Micro-encapsulation of islets for the treatment of Type I diabetes has shown limited efficacy in small-scale clinical trials. The lack of success may be related…
2016 American Transplant Congress
Diagnosis of Pulmonary Nocardiosis: A Single Center Study.
D. Wray,¹ S. Win,² M. Heincelman,¹ L. Steed,¹ J. Cantey.¹
¹Medical University of South Carolina, Charleston, SC; ²Los Palos Medical Associates, Salinas, CA.
Pulmonary nocardiosis (PN) is an uncommon infection seen typically in immunocompromised (IC) patients. Definitive diagnosis depends on culture of nocardia along with a clinical presentation…
2016 American Transplant Congress
The Preventive and Therapeutic Effect of Immunoglobulin on Infectious Complications in Donation After Cardiac Death Liver Transplant Recipients: A Prospective Randomized Controlled Study.
A. Yang, Z. Guo, W. Ju, Y. Chen, M. Han, X. Wang, D. Wang, Y. Ma, A. Hu, X. Zhu, X. He.
Organ Transplantation Center, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China.
Aims: To prospectively investigate the preventive and therapeutic effect of immunoglobulin on infectious complications in DCD liver transplant recipients, and synthetically evaluate its influence on…
2016 American Transplant Congress
Post-Trial Experience with Belatacept: A Large Single Center Experience.
A. Adams, C. Garrett, J. Goldstein, R. Zhang, A. Guasch, S. Pastan, R. Patzer, A. Kirk, T. Pearson, C. Larsen.
Emory Transplant Center, Atlanta, GA.
Evaluation of belatacept in clinical trials revealed significant improvements in renal function and cardiovascular risk leading to superior survival. Despite these proven benefits higher rates…
2016 American Transplant Congress
Vaccination Status and Titers Before and After Pediatric Renal Transplantation: An Analysis of the CERTAIN Registry.
B. Höcker,¹ M. Aguilar,¹ P. Schnitzler,² L. Pape,² L. Dello Strologo,² N. Webb,² M. Bald,² G. Genc,² H. Billing,² J. König,² A. Büscher,² F. Thiel,² S. Marks,² M. Pohl,² M. Wigger,² R. Topaloglu,² A. Fichtner,¹ S. Rieger,¹ K. Krupka,¹ B. Tönshoff.¹
¹University Children's Hospital, Heidelberg, Germany; ²CERTAIN Research Community, Italy, United Kingdom, Turkey, Germany.
Purpose:Prevention of systemic viral and bacterial infections by effective vaccination in kidney allograft recipients is of vital importance, but data on the vaccination status in…
2016 American Transplant Congress
Incidence of Post-Transplant Cardiovascular Disease After Pediatric Kidney Transplantation.
O. Serrano,¹ A. Bangdiwala,² D. Vock,² W. Payne,¹ T. Dunn,¹ S. Chinnakotla,¹ E. Finger,¹ R. Kandaswamy,¹ T. Pruett,¹ A. Matas,¹ B. Chavers.³
¹Surgery, Univ. of Minnesota, Minneapolis, MN; ²Biostatistics, Univ. of Minnesota, Minneapolis, MN; ³Pediatrics, Univ. of Minnesota, Minneapolis, MN.
PURPOSE: Kidney transplant (KTx) recipients have increased risk of cardiovascular disease (CVD), related to time on dialysis and post-KTx immunosuppression. To date, the incidence of…

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