2015 American Transplant Congress
Banff Criteria Are Inadequate to Assess Chronic Renal Allograft Injury 10 Years Post-Transplantation
Background: The Banff criteria have been developed to assess acute and chronic injury in renal allografts. However, the criteria have been based on biopsies for…2015 American Transplant Congress
Morphometry of the Epithelial-Mesenchymal Transition (EMT) in Subsequent Biopsies from Transplanted Kidney
EMT plays the principal role in the pathogenesis of IF/TA as a consequence in the failure of a transplanted kidney. Many facts suggest that the…2015 American Transplant Congress
Outcome of Kidney Transplantation from Older Living Donors: Histological Evaluation Using Zero-Time Biopsy Specimens
OBJECTIVE: The relationship between preimplantation biopsy and graft outcome in kidney transplantations from older living donors has not been studied yet. We reviewed graft outcomes…2015 American Transplant Congress
Outcome of Kidney Transplantation from Obese Living Donors: Histological Evaluation Using Zero-Time Biopsy Specimens
BACKGROUND AND OBJECTIVE: The relationship between preimplantation biopsy and graft outcome in kidney transplantation from obese living donors has not been studied. We reviewed graft…2015 American Transplant Congress
Transplant Glomerulopathy in a Novel Model of Chronic Antibody Mediated Rejection Is Associated With DSA and Glomerular IgM
PurposeChronic active antibody mediated rejection (cAMR) and transplant glomerulopathy (TG) are major determinants of long-term allograft survival. However, the contribution of DSA and glomerular immunoglobulins…2015 American Transplant Congress
Distinct Subtypes of Rejection in a Novel Non Human Primate Model of Sensitization
[Background] Preformed and newly formed alloantibody post transplantation (TX) can significantly deteriorate graft survival. Patterns of humoral rejection in sensitized patients varies significantly due to…2015 American Transplant Congress
Reduction of Tacrolimus With Everolimus Addition in Maintenance Immunosuppression Improves Calcineurin Inhibitor-Induced Arteriolopathy in Kidney Allografts
Objectives: Although conversion of calcineurin inhibitor (CNI)-based immunosuppression to everolimus (EVR) has been shown to improve graft function, no histopathological evidence has been reported. The…2015 American Transplant Congress
A Prospective Study of Renal Function and Histological Changes in Renal Transplant Recipients With Acute Clinical and Subclinical Rejection
Background: To study the impact on renal function and histological changes in patients(pts) with acute clinical rejection(ACR) and subclinical rejection(SCR) from 3 to 12 month(m)…2015 American Transplant Congress
Association Between Histological Abnormalities in Time-Zero Renal Biopsies and Post-Donation eGFR in Live Donors
Time-zero biopsies (T0-RBx) of live-donor kidneys may reveal histological abnormalities at the time of organ recovery. The association between T0-RBx and subsequent kidney function in…2015 American Transplant Congress
Deceased Donor and Class II Donor Specific Antibody Predict Interface Activity While Increased Age at Time of Biopsy Predicts Fibrosis in Long-Term Pediatric Liver Allografts With Normal Liver Tests: iWITH Clinical Trial
Background: Although multiple single centers have reported deterioration of pediatric liver grafts in the face of normal liver tests, neither risk nor mechanism is understood.Methods:…