2015 American Transplant Congress
Repeat Donor HLA Mismatch Antigens and Kidney Transplant Outcome
Background: Historically, poorer outcome has been reported in kidney re-transplant patients with repeat HLA mismatch antigens. Transplant practice has evolved. Risk of repeat mismatch antigen…2015 American Transplant Congress
Efficacy and Safety of Induction Therapy With Monoclonal Versus Polyclonal Antibodies in Kidney Transplant Recipients in the Last Five Years (2008-2013) in Our Institution
Nephrology, La Paz Hospital, Madrid, Spain.
Induction immunosuppression in renal transplantation is not clearly defined. We analyze the efficacy and safety of the used regimens at our institution in the last…2015 American Transplant Congress
Tacrolimus Trough Concentrations Increase in Intestinal Transplant Recipients During Episodes of Acute Cellular Rejection
Introduction: Acute cellular rejection (ACR) in small bowel transplant recipients is expected to increase intestinal permeability and to reduce intestinal CYP3A/p-glycoprotein activity. These changes may…2015 American Transplant Congress
Non-Inferiority of Graft Survival of Living Unrelated Kidney Transplant compared to Living Related Kidney Transplant as Analyzed by First Degree Relative
Henry Ford Transplant Institute, Detroit, MI.
The perceived advantage of donating a kidney directly to a family member is difficult to uncouple in the setting of voluntary exchange or other kidney…2015 American Transplant Congress
Transplant Glomerulopathy in a Novel Model of Chronic Antibody Mediated Rejection Is Associated With DSA and Glomerular IgM
PurposeChronic active antibody mediated rejection (cAMR) and transplant glomerulopathy (TG) are major determinants of long-term allograft survival. However, the contribution of DSA and glomerular immunoglobulins…2015 American Transplant Congress
Does Switching Predict Conversion: IgM De Novo Donor Specific HLA Antibodies Class Switch to IgG in Subclinical Antibody Mediated Rejection in Heart Transplant Recipients
1Cleveland Clinic, Cleveland; 2School of Medicine, Leipzig University, Leipzig, Germany.
Background: Concomitant C4d and C3d detection in heart biopsies correlates with circulating DSA and graft dysfunction. Detection of C4d only in surveillance biopsies is not…2015 American Transplant Congress
An Orchestrated Sequence of Innate and Adaptive Immune Responses Is Associated With Rejection After Pediatric Liver Transplantation
The concept of a coordinated immune response initiated by innate and sustained by adaptive immune cells and their soluble mediators is well established for infection…2015 American Transplant Congress
The Clinical Outcome of Plasma Cell-Rich Rejection of Kidney Allograft
Background: Plasma cell-rich rejection (PCRR) is a rare type of allograft rejection characterized by the presence of mature plasma cells. This type of rejection has…2015 American Transplant Congress
Changes in Health Related Quality of Life (HRQOL) in Pediatric Liver Transplant (LT) Recipients During Protocolized Immunosuppression Withdrawal (ISW): The iWITH Trial
ISW may limit medication-related comorbidities but intensive monitoring and unexpected rejection episodes may compromise HRQOL. We studied longitudinal HRQOL in pediatric LT recipients undergoing ISW…2015 American Transplant Congress
Immunoglobulin G Donor-Specific Anti-HLA Antibody Subclasses and Kidney Allograft Antibody-Mediated Injury
Experimental and clinical data suggest that antibodies have different pathogenicities according to their IgG subclasses. We investigated the association between IgG subclasses of circulating anti-HLA…
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