Articles tagged "Proteinuria"

2022 American Transplant Congress
Dietary Sodium Intake And Blood Pressure In Living Kidney Donors (SPLID): Rationale And Design Of A Pilot Single-center Crossover Single-blind Randomized Controlled Trial
E. Tantisattamo¹, U. G. Reddy¹, A. J. Ferrey¹, H. Ichii², D. C. Dafoe², H. Moradi¹, C. M. Rhee¹, K. Kalantar-Zadeh¹
¹Division of Nephrology, Hypertension and Kidney Transplantation, Department of Medicine, University of California Irvine School of Medicine, Orange, CA, ²Division of Kidney and Pancreas Transplantation, Department of Surgery, University of California Irvine School of Medicine, Orange, CA
*Purpose: Since living kidney donors(LKD) are generally healthy and non-hypertensive individuals, non-pharmacologic interventions are likely to be an acceptable and practical approach to preventing hypertension(HTN).…
2022 American Transplant Congress
Intermediate Term Outcomes of SGLT2 Inhibitors Amongst Diabetic Kidney Transplant Recipients
C. Song¹, A. Brown², R. Winstead¹, S. Sterling¹, I. Yakubu², J. Christensen², G. Gupta²
¹Pharmacy, VCUHS, Richmond, VA, ²VCUHS, Richmond, VA
*Purpose: The use of Sodium Glucose Linked Transporter Inhibitors (SGLT-2i) among non-transplant diabetic patients with chronic kidney disease (CKD) has demonstrated reduced cardiovascular mortality, delayed…
2022 American Transplant Congress
Clinical Evolution of Patients with De Novo DSA After Kidney Transplantation
C. López del Moral¹, N. Lachmann², S. Hergovits², D. Stauch², A. Akifova³, M. Naik³, B. Osmanodja³, D. Schmidt³, K. Budde³
¹Nephrology department-IDIVAL, Hospital Universitario Marqués de Valdecilla, Santander, Spain, ²Institute for Transfusion Medicine, HLA-Laboratory, Charité - Universitätsmedizin, Berlin, Germany, ³Department of Nephrology and Medical Intensive Care, Charité - Universitätsmedizin, Berlin, Germany
*Purpose: De novo donor-specific antibodies(dnDSA) are related to antibody-mediated rejection(ABMR), but the evolution of patients after dnDSA is variable and not always ABMR and graft…
2022 American Transplant Congress
Association of Change in Kidney Volume with Proteinuria After Donation
M. Tsujita¹, K. Uchida¹, K. Morozumi¹, K. Futamura², T. Hiramitsu², M. Okada², S. Narumi², N. Goto², Y. Watarai²
¹Masuko Memorial Hospital, Nagoya, Japan, ²Japanese Red Cross Aichi Medical Center Nagoya Daini Hospital, Nagoya, Japan
*Purpose: In living kidney transplantation, the risk of end-stage kidney disease in kidney donors is crucial, however, it still remains to be resolved. Any useful…
2022 American Transplant Congress
Utilisation and Clinical Outcomes of Kidney Transplants from Deceased Donors with Albuminuria in the UK: A Cohort Study
G. Greenhall¹, M. Robb¹, R. Johnson¹, M. Ibrahim¹, R. Hilton², L. Tomlinson³, C. J. Callaghan², C. Watson⁴
¹NHS Blood and Transplant, Bristol, United Kingdom, ²Guy's Hospital, London, United Kingdom, ³London School of Hygiene and Tropical Medicine, London, United Kingdom, ⁴University of Cambridge, Cambridge, United Kingdom
*Purpose: Urinalysis is a standard component of the assessment of potential deceased kidney donors in the UK. The value of albuminuria as a biomarker for…
2022 American Transplant Congress
Belatacept Conversion in Proteinuric Kidney Transplant Recipients: Effects in a Prospective Trial and a Retrospective Cohort
O. Efe¹, A. Al Jurdi¹, D. Wojciechowski², K. Safa¹, H. Gilligan¹, A. Chandraker³, J. Azzi³, A. Weins³, L. V. Riella¹
¹Center for Transplantation Sciences, Massachusetts General Hospital, Charlestown, MA, ²UT Southwestern Medical Center, Dallas, TX, ³Brigham and Women's Hospital, Boston, MA
*Purpose: Proteinuria after kidney transplantation is associated with worse allograft outcomes. B7-1 expression by podocytes has been linked to proteinuria by inducing podocyte migration which…
2022 American Transplant Congress
Plasmapheresis and Rituximab for Prevention of Focal Segmental Glomerulosclerosis Recurrence Post-Kidney Transplantation
A. N. Yun¹, A. W. Rogers¹, J. C. Krisl¹, A. Kagan², H. E. Adrogue², A. J. Khan², P. Khairallah², S. G. Yi³, M. J. Hobeika³, R. R. McMillan³, H. Podder³, A. O. Gaber³, R. J. Knight³
¹Pharmacy, Houston Methodist Hospital, Houston, TX, ²Nephrology, Houston Methodist Hospital, Houston, TX, ³Surgery, Houston Methodist Hospital, Houston, TX
*Purpose: Primary focal segmental glomerulosclerosis (FSGS) recurs after kidney transplantation (KT) in 30-50% of recipients with a median time of 1.5 months post-KT. Recurrence is…
2022 American Transplant Congress
Proteome Profiling of Recurrent Primary Focal Segmental Glomerulosclerosis (FSGS) Plasma Samples Reveals Potential Proteins Involved in Primary FSGS
L. Gallon¹, N. Ahsan², V. Mas³, J. Leventhal¹, L. Fornelli²
¹Northwestern Univ NMFF, Chicago, IL, ²Mass Spectrometry, Proteomics and Metabolomics Core Facility, Department of Chemistry and Biochemistry, The University of Oklahoma, Oklahoma, OK, ³University of Maryland, Baltimore, MD
*Purpose: The presumed etiology of primary FSGS is a plasma factor that results in general podocyte dysfunction with partial and/or unpredictable response to immunosuppressive therapy…
2022 American Transplant Congress
Impact of Varying Levels of Normal Range Baseline Donor Derived Cell Free DNA on Medium-Term Outcomes Following Kidney Transplantation
K. K. Sureshkumar¹, A. Grazier², B. Chopra¹
¹Nephrology, Medicine Institute, Allegheny General Hospital, Pittsburgh, PA, ²Abdominal Transplantation, Allegheny General Hospital, Pittsburgh, PA
*Purpose: Donor derived cell free DNA (dd-cfDNA) is a biomarker with high negative predictive value for ruling out acute rejection (AR) in kidney allografts. Baseline…
2022 American Transplant Congress
Adverse Renal Events After BNT162b2 Pfizer/BioNTech COVID-19 Vaccine in Kidney Transplant Recipients
H. K. Sran¹, E. Wong¹, M. R. D'Costa², A. Lim², Q. Lim², A. Vathsala¹
¹National University of Singapore, Singapore, Singapore, ²National University Centre for Organ Transplantation, National University Hospital, Singapore, Singapore
*Purpose: Adverse events of a novel mRNA vaccine are not well described in Kidney Transplant Recipients(KTR), especially the risk of immune activation or recurrent glomerulonephritis(GN),…

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