ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Polyma virus"

  • 2016 American Transplant Congress

    BK Polyomavirus Seroreactivity of Kidney Donors Predicts Viremia and Nephropathy in Recipients.

    H. Wunderink,1 E. van der Meijden,1 C. van der Blij-de Brouwer,1 M. Mallat,2 G. Haasnoot,3 E. van Zwet,4 E. Claas,1 J. de Fijter,3 A. Kroes,1 F. Arnold,5 A. Touzé,5 F. Claas,3 J. Rotmans,3 M. Feltkamp.1

    1Medical Microbiology, LUMC, Leiden, Netherlands; 2Nephrology, LUMC, Leiden, Netherlands; 3Immunohematology and Blood Transfusion, LUMC, Leiden, Netherlands; 4Medical Statistics and Bioinformatics, LUMC, Leiden, Netherlands; 5UMR INRA 1282 ISP, Université François Rabelais, Tours, France.

    Background Kidney transplant (KTx) donors are not implicated in predicting BK polyomavirus (BKV) infection in the recipient. For BKV-associated nephropathy (BKVAN) however, donor origin of…
  • 2015 American Transplant Congress

    Concerted T-Cell Activity Against Early and Late BKV-Antigens Is Necessary for Viral Clearance

    B. Weist,1,2 M. Schmueck,2 M. Dziubianau,2 P. Reinke,1,2 N. Babel.1,2

    1Department of Nephrology, Charite Universitaetsmedizin, Berlin, Germany; 2BCRT, Charite Universitaetsmedizin, Berlin, Germany.

    Polyomavirus-BK (BKV) associated nephropathy is a known cause of graft failure. No specific therapy is established so far and viral load monitoring accompanied by adjustment…
  • 2015 American Transplant Congress

    Impact of Sirolimus on the Risk of BK Viremia in Simultaneous Pancreas-Kidney Transplant Recipients

    D. Wojciechowski, T. Yokoyama, S. Chandran, P. Stock.

    UCSF, San Francisco.

    BackgroundBK virus (BKV) is a common infection in simultaneous pancreas-kidney (SPK) transplant recipients. Data in kidney transplant recipients suggest that immunosuppression regimens containing an mTORi…
  • 2015 American Transplant Congress

    Alemtuzumab Induction Is Associated With Higher Risk of Polyomavirrus Associated Nephropathy (PVAN) in Kidney Transplant Recipients

    H. Wadei,1 H. Saull,2 C. Enderby,2 M. Mai,1 M. Prendergast,1 T. Gonwa.1

    1Transplant, Mayo Clinic, Jacksonville, FL; 2Pharmacy, Mayo Clinic, Jacksonville, FL.

    Incidence of PVAN on protocol kidney biopsies with alemtuzumab induction is unknown.Methods:The 1-year risk of PVAN was retrospectively compared between 200 consecutive primary kidney recipients…
  • 2015 American Transplant Congress

    A Single Center Comparison of Various BK Viremia Elimination Protocols

    Y. Qazi, K. Lee, B. Duong, R. Dhawan, L. Shinn, L. Aguirre, C. Parke, C. Wong, S. Alexopoulos, D. Olson, M. Smogorzewski.

    Division of Transplantation, University Of Southern California. Keck Med Center, Los Angeles, CA.

    Aim BK infection remains a significant complication post kidney transplantation. Best practices in BK management have evolved over time. The purpose of the study was…
  • 2015 American Transplant Congress

    Donor and Recipient Pretransplant Polyoma BK Serostatus: Relationship to BK-Viremia After Renal Transplantation

    H. Tseng, R. Lopez-Soler, N. Chandolias, T. Friedrich, J. Eldor, D. Conti.

    Surgery, Albany Medical College, Albany, NY.

    Background:Polyoma virus BK nephropathy is a serious complication after renal transplantation and is associated with a significant risk of graft loss and dysfunction. This study…
  • 2015 American Transplant Congress

    Evaluation of the Use of Leflunomide for the Prevention of BK Nephropathy in Renal Transplant Recipients- A Single Center Experience

    S. Jonchhe, E. Hollinger, S. Jensik, O. Olaitan, A. Hodowanec, M. Hertl, S. Fayek, E. Chan, C. Pullum, N. Alvey.

    Rush University Medical Center, Chicago, IL.

    Objective: The purpose of this study was to compare the efficacy of leflunomide in combination with reduced immunosuppression versus reduction of immunosuppression alone for the…
  • 2015 American Transplant Congress

    Is BK Viral Subtype Distribution of Donor And/Or Recipient Important for Subsequent BK Viral Infection After Living-Donor Transplantation?

    A. Schwarz,1 S. Linnenweber-Held,1 H. Haller,1 A. Heim,2 C. Schmitt.2

    1Nephrology, Hannover Medical School, Hannover, Germany; 2Virology, Hannover Medical School, Hannover, Germany.

    Background: Source and risk factors for developing BK virus (BKV) infection after renal transplantation are unresolved. By genotyping of urine and blood, we looked for…
  • 2015 American Transplant Congress

    Evaluation of Leflunomide for the Treatment of BK Viremia and Biopsy Proven BK Nephropathy: A Single Center Experience

    N. Nesselhauf,1 J. Strutt,2 B. Bastani.1

    1Saint Louis University Hospital, St. Louis, MO; 2Minneapolis VA Health Care System, Minneapolis, MN.

    Purpose:The objective was to evaluate the use of leflunomide in BK viremia (BKV) and biopsy proven BK nephropathy (BKN) in kidney and kidney-pancreas transplant recipients.Methods:We…
  • 2015 American Transplant Congress

    Impact of Donor and Recipient BKV Serostatus and the Effect of Ciprofloxacin Prophylaxis on BK Viremia Risk After Kidney Transplant

    M. Changala,1 A. Kistler,2 J. Abend,2 A. Sathe,2 A. Howard,1 D. Wojciechowski.1

    1University of California, San Francisco, San Francisco, CA; 2Novartis Institutes for Biomedical Research, Emeryville, CA.

    Background: BK virus (BKV) is a common infection in kidney transplant recipients. Due to widespread latent BKV infection in the general population, it is possible…
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