Articles tagged "Polyma virus"

2016 American Transplant Congress
Simultaneous Pancreas/Kidney Transplantation Increases the Risk of Late-Onset BKV-Associated Nephropathy.
T. Schachtner,^1,2 M. Zaks,¹ A. Kahl,¹ P. Reinke.^1,2
¹Nephrology and Internal Intensive Care, Charite Campus Virchow Clinic, Berlin, Germany; ²Berlin-Brandenburg Center for Regenerative Therapies, Charite Campus Virchow Clinic, Berlin, Germany.
Infections have increased in simultaneous pancreas/kidney transplant recipients (SPKTRs) with BKV-associated nephropathy (BKVN) being the most important infectious cause of allograft loss. Comparisons of BKVN…
2016 American Transplant Congress
New England BK Consortium: Regional Survey of BK Screening and Management Protocols in Comparison to Published Consensus Guidelines.
S. Gabardi, M. Pavlakis, C. Tan, J. Francis, F. Cardarelli, W. Asch, K. Bodziak, M. Chobanian, H. Gilligan, R. Gohh, S. Kung, L. Inker, S. Martin, N. Rodig, A. Rossi, A. Chandraker.
New England BK Consortium, Boston, MA.
Introduction: BK virus (BKV) continues to impact renal transplant recipients (RTR). The New England BK Consortium was formed to unite the leadership of 14 transplant…
2016 American Transplant Congress
Results of a Biopsy Based, Early Intervention Treatment Protocols for BK Viraemia and BK Virus Associated Nephropathy.
S. Jones,¹ S. Waller,¹ K. Lai,^2,3 A. Hibbard,¹ P. Trevillian,¹ M. Heer.¹
¹Newcastle Transplant Unit, John Hunter Hospital, Newcastle, NSW, Australia; ²Infectious Diseases and Immunology Department, John Hunter Hospital, Newcastle, NSW, Australia; ³University of Newcastle, Newcastle, NSW, Australia.
Background: Following the death of a renal transplant recipient (RTR) in 2003 following BK Virus associated nephropathy (BKVAN) and acute rejection, our centre adopted protocols…
2016 American Transplant Congress
Evaluation of Polyomavirus (BK) Treatment and Clinical Outcomes in Pediatric Kidney Transplant Recipients: A >10 Year Single Center Retrospective Experience.
R. Liverman,¹ E. Kraus,¹ R. Garro,² B. Warshaw,² P. Winterberg,² R. George.²
¹Children's Healthcare of Atlanta, Atlanta, GA; ²Division of Pediatric Nephrology, Emory University School of Medicine, Atlanta, GA.
BK viremia (BKV) is a serious infectious complication after kidney transplantation and can lead to BK nephropathy (BKN) and allograft loss. We reviewed our experience…
2016 American Transplant Congress
Incidence of Polyoma Virus Associated Nephropathy in a Single Transplant Center Employing a Reduction of Immunosuppression at a Lower Threshold of BK Viremia.
M. Azar, A. Valika, D. Banach, I. Hall, M. Malinis.
Internal Medicine, Infectious Diseases, Yale University, New Haven, CT.
BackgroundPolyoma virus associated nephropathy (PyVAN) caused by BK virus (BKV) is a major complication occurring in 1-10% of renal transplant recipients. Screening and reduction of…
2016 American Transplant Congress
BK Viremia Surveillance and Management in Simultaneous Pancreas-Kidney Transplants.
S. Westphal, C. Miles.
Internal Medicine, University of Nebraska Medical Center, Omaha, NE.
BK virus nephropathy is an important cause of kidney allograft dysfunction, and the mainstay of management is reduction of immunosuppression. In recipients of multiorgan transplants,…
2016 American Transplant Congress
Urinary Virome in Human Kidney Transplants Reveals Multiple Virus Subtypes with Distinct Genome Polymorphisms.
R. Ranjan,¹ A. Rani,¹ H. McGee,¹ D. Brennan,² P. Finn,¹ D. Perkins.^1,3
¹Medicine, University of Illinois, Chicago, IL; ²Division of Renal Diseases, Washington University School of Medicine, St. Louis, MO; ³Surgery, University of Illinois, Chicago, IL.
Recent studies have established that human urine has its own unique microbiome, but little is known about the virome. The human virome is the collection…
2016 American Transplant Congress
Autologous BK-Specific T-Cell Lines in Kidney Transplant Recipients.
C. Lamarche,^1,2,3 O. Julie,^1,3 C. Carli,^1,3 J.-S. Delisle.^1,2,3
¹Centre de Recherche de l'Hôpital Maisonneuve-Rosemont, Montreal, QC, Canada; ²Canadian National Transplant Research Program (CNTRP), Edmonton, Canada; ³ThéCell Network, Quebec, Canada.
Background: More than 75% of the population has been exposed to BK polyomavirus and carries latent virus in the uroepithelium. Immunocompetent hosts are asymptomatic but…
2016 American Transplant Congress
Potential Biomarkers and Treatment for BK Virus Associated Nephropathy.
M. Borkar,¹ V. Srivastava,² R. Cunnington,¹ T. Sharma,¹ L. Tibbles.¹
¹Faculty of Mediicne, University of Calgary, Calgary, AB, Canada; ²CSIR-Indian Institute of Toxicology Research, Lucknow, Uttar Pradesh, India.
Background: BK polyomavirus assoiciated nephropathy (BKVAN) is one of the major complications in renal transplants, and is associated with significant fibrosis It is important to…
2016 American Transplant Congress
Sequential and Long-Term Protocol Biopsy Is Useful for the Detection of Subclinical Lesions of Clinical Interest in Kidney Allografts.
M. Miura,¹ H. Higashiyama,¹ T. Tsuji,² Y. Fukasawa.²
¹Department of Urology and Renal Transplantation Surgery, Sapporo Hokuyu Hospital, Sapporo, Japan; ²Department of Pathology, Sapporo City General Hospital, Sapporo, Japan.
Objectives: Detection of subclinical lesions is important to overcome the obstacles to improve long-term graft survival after kidney transplantation. The aim of this study was…