2017 American Transplant Congress
BK Virus in Simultaneous Pancreas Kidney Transplantation.
BK virus (BKV) may produce nephropathy that could lead to graft failure. The most effective treatment is to decrease immunosuppression (IS). In simultaneous pancreas kidney…2017 American Transplant Congress
Impact of Everolimus Added to a De Novo Belatacept Regimen on the Risk of BK Viremia After Kidney Transplant.
IntroductionBK viremia is a common complication following kidney transplantation. In vitro data suggest that inhibition of the mTOR–SP6-kinase pathway prevents expression of early viral genes…2017 American Transplant Congress
CMV and BK Virus Infections in Kidney Transplant Recipients Receiving an mTORi-Based Regimen versus a CNI-Based Regimen: A Systematic Review and Meta-Analysis.
The objective of this systematic review is to compare the incidence of CMV and BK virus infections in kidney transplant recipients receiving an mTORi-based as…2017 American Transplant Congress
BK Virus Infection and Risk of Urinary Tract Cancers Among Kidney Transplant Patients in the Transplant Cancer Match Study.
Background: Recent case series describe expression of BK virus (BKV) in tumor tissue obtained from renourinary cancers in kidney transplant recipients (KTRs). Thus, BKV may…2017 American Transplant Congress
BK Polyoma Virus and Malignancy: Cause or Co-Incidence?
Henry Ford Transplant Institute, Detroit, MI
BackgroundThe WHO agency for cancer research has classified BKV as "possibly carcinogenic".The etiological role of BKV in human cancer, however,remains controversial.We present 5 cases of…2017 American Transplant Congress
BK Polyomavirus-Specific 9mer T-Cell Responses Predict Control of Viremia in Kidney Transplant Recipients: First Report from the Swiss Transplant Cohort Study.
BK polyomavirus (BKPyV) causes premature kidney transplant (KT) failure in 1-15% of patients. Since antivirals are lacking, most programs screen KT patients for BKPyV viremia…2017 American Transplant Congress
BK Viruria Levels within 3 Months Post Renal Transplantation Can Predict the Development of BK Viraemia.
Aim: To determine the utility of screening for BK viruria (BKVR) to predict the development of BK viraemia within the first year of renal transplantation.Background:…2017 American Transplant Congress
Noninvasive Prognostication of Renal Allograft Failure Following BK Virus Associated Nephropathy – A Validation Study.
Transplant Medicine, Weill Cornell Medicine, NY, NY
Introduction. Identification of kidney transplant (KTx) recipients at risk for graft loss following BKVN diagnosis may allow personalization of immunosuppressive protocols. Previous study demonstrated that…2017 American Transplant Congress
Increased Gene Expression of TGF-β in Peripheral Blood Mononuclear Cells from Renal Transplant Patients with Polyomavirus BK Viremi.
We aimed to investigate the roles of cytokines during polyomavirus BK (BKV) reactivation in renal transplant patients. Forty-eight renal allograft recipients were enrolled in this…2017 American Transplant Congress
Impact of Donor BK-Virus Replication on Posttransplant BKV Replication After Living-Donor Transplantation.
Department of Nephrology and Organ Transplantation, Toulouse University Hospital, Toulouse, France
BK-virus-associated nephropathy (BKVAN) can cause kidney-allograft dysfunction after kidney transplantation: several risk factors for BKV replication after kidney transplantation have been identified. They can be…
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