Articles tagged "Polyma virus"

2017 American Transplant Congress
CMV and BK Virus Infections in Kidney Transplant Recipients Receiving an mTORi-Based Regimen versus a CNI-Based Regimen: A Systematic Review and Meta-Analysis.
B. Tanios,¹ S. Mallat,¹ H. Itani,¹ T. Lotfi,¹ S. Gabardi,² E. Akl,¹ J. Azzi.²
¹Division of Nephrology, American University of Beirut Medical Center, Beirut, Lebanon; ²Renal Division, Harvard Medical School, Boston
The objective of this systematic review is to compare the incidence of CMV and BK virus infections in kidney transplant recipients receiving an mTORi-based as…
2017 American Transplant Congress
BK Virus Infection and Risk of Urinary Tract Cancers Among Kidney Transplant Patients in the Transplant Cancer Match Study.
G. Gupta,¹ S. Kuppachi,² R. Kalil,² C. Buck,³ C. Lynch,² E. Engels.³
¹Virginia Commonwealth University, Richmond; ²University of Iowa, Iowa City; ³National Cancer Institute, Bethesda
Background: Recent case series describe expression of BK virus (BKV) in tumor tissue obtained from renourinary cancers in kidney transplant recipients (KTRs). Thus, BKV may…
2017 American Transplant Congress
BK Polyoma Virus and Malignancy: Cause or Co-Incidence?
R. Prashar, A. Shah, D. Stewart, S. Williamson, A. Patel.
Henry Ford Transplant Institute, Detroit, MI
BackgroundThe WHO agency for cancer research has classified BKV as "possibly carcinogenic".The etiological role of BKV in human cancer, however,remains controversial.We present 5 cases of…
2017 American Transplant Congress
BK Polyomavirus-Specific 9mer T-Cell Responses Predict Control of Viremia in Kidney Transplant Recipients: First Report from the Swiss Transplant Cohort Study.
H. Hirsch,¹ C. Leboeuf,¹ S. Wilk,¹ R. Achermann,² I. Binet,³ D. Golshayan,² K. Hadaya,² C. Hirzel,² M. Hoffmann,² U. Huynh-Do,² M. Koller,² O. Manuel,² N. Mueller,² T. Mueller,² S. Schaub,² C. Van Delden,² F. Weissbach.¹
¹University of Basel, Basel, Switzerland; ²Swiss Transplant Cohort Study, Basel, Switzerland; ³Cantonal Hospital St Gallen, St Gallen, Switzerland
BK polyomavirus (BKPyV) causes premature kidney transplant (KT) failure in 1-15% of patients. Since antivirals are lacking, most programs screen KT patients for BKPyV viremia…
2017 American Transplant Congress
BK Viruria Levels within 3 Months Post Renal Transplantation Can Predict the Development of BK Viraemia.
N. Lioufas,¹ R. Masterson,^1,2 P. Hughes.
¹Department of Nephrology, Royal Melbourne Hospital, Parkville, Victoria, Australia; ²Department of Medicine, The University of Melbourne, Parkville, Victoria, Australia
Aim: To determine the utility of screening for BK viruria (BKVR) to predict the development of BK viraemia within the first year of renal transplantation.Background:…
2017 American Transplant Congress
Noninvasive Prognostication of Renal Allograft Failure Following BK Virus Associated Nephropathy – A Validation Study.
E. Abuhelaiqa, C. Snopkowski, C. Li, J. Lee, T. Muthukumar, H. Yang, M. Suthanthiran, D. Dadhania.
Transplant Medicine, Weill Cornell Medicine, NY, NY
Introduction. Identification of kidney transplant (KTx) recipients at risk for graft loss following BKVN diagnosis may allow personalization of immunosuppressive protocols. Previous study demonstrated that…
2017 American Transplant Congress
Increased Gene Expression of TGF-β in Peripheral Blood Mononuclear Cells from Renal Transplant Patients with Polyomavirus BK Viremi.
W. Yin.^1,2
¹Surgery, Dalin Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Dalin, Taiwan; ²School of Medicine, Tzu Chi University, Hualien, Taiwan
We aimed to investigate the roles of cytokines during polyomavirus BK (BKV) reactivation in renal transplant patients. Forty-eight renal allograft recipients were enrolled in this…
2016 American Transplant Congress
Results of a Biopsy Based, Early Intervention Treatment Protocols for BK Viraemia and BK Virus Associated Nephropathy.
S. Jones,¹ S. Waller,¹ K. Lai,^2,3 A. Hibbard,¹ P. Trevillian,¹ M. Heer.¹
¹Newcastle Transplant Unit, John Hunter Hospital, Newcastle, NSW, Australia; ²Infectious Diseases and Immunology Department, John Hunter Hospital, Newcastle, NSW, Australia; ³University of Newcastle, Newcastle, NSW, Australia.
Background: Following the death of a renal transplant recipient (RTR) in 2003 following BK Virus associated nephropathy (BKVAN) and acute rejection, our centre adopted protocols…
2016 American Transplant Congress
Evaluation of Polyomavirus (BK) Treatment and Clinical Outcomes in Pediatric Kidney Transplant Recipients: A >10 Year Single Center Retrospective Experience.
R. Liverman,¹ E. Kraus,¹ R. Garro,² B. Warshaw,² P. Winterberg,² R. George.²
¹Children's Healthcare of Atlanta, Atlanta, GA; ²Division of Pediatric Nephrology, Emory University School of Medicine, Atlanta, GA.
BK viremia (BKV) is a serious infectious complication after kidney transplantation and can lead to BK nephropathy (BKN) and allograft loss. We reviewed our experience…
2016 American Transplant Congress
Incidence of Polyoma Virus Associated Nephropathy in a Single Transplant Center Employing a Reduction of Immunosuppression at a Lower Threshold of BK Viremia.
M. Azar, A. Valika, D. Banach, I. Hall, M. Malinis.
Internal Medicine, Infectious Diseases, Yale University, New Haven, CT.
BackgroundPolyoma virus associated nephropathy (PyVAN) caused by BK virus (BKV) is a major complication occurring in 1-10% of renal transplant recipients. Screening and reduction of…