Articles tagged "Outcome"

2015 American Transplant Congress
Elevated ST2 Levels Are Associated With Increased Risk of Antibody Mediated Rejection in Heart Transplant Recipients
A. Grupper,¹ S. Kushwaha,¹ O. Abou Ezzeddine,¹ J. Geske,² W. Kremers,² B. Edwards,¹ N. Pereira.¹
¹Division of Cardiovascular Diseases, Mayo Clinic, Rochester, MN; ²Division of Biomedical Statistics and Informatics, Mayo Clinic, Rochester, MN.
Objective: Serum ST2, a member of the interleukin (IL) 1 receptor family, is a novel biomarker that reflects cardiac remodeling and fibrosis and is associated…
2015 American Transplant Congress
Alemtuzumab Induction Has Been Safe in the United Kingdom and Achieves Long-Term Steroid Avoidance in More Than 80% of Low Risk Renal Transplant Recipients
A. Seitz,¹ M. Robb,³ S. Balasubramanian,¹ A. McLean,² D. Taube,² R. Johnson,³ R. Baker.¹
¹Renal Unit, St. James's Hospital, Leeds, United Kingdom; ²West London Renal and Transplant, Hammersmith Hospital, London, United Kingdom; ³Organ Donation and Transplantation Studies, NHS Blood and Transplant, Bristol, United Kingdom.
Introduction: The use of alemtuzumab as an induction agent for renal transplantation is increasing in the UK. There is some evidence to suggest that this…
2015 American Transplant Congress
Treatment of Subclinical Rejection Identified On Surveillance Biopsy May Prevent the Development of Chronic Alloimmune Injury
M. Willicombe, C. Roufosse, J. Galliford, A. McLean, D. Taube.
Imperial College Kidney and Transplant Centre, Hammersmith Hospital, London, United Kingdom.
Surveillance biopsies [SBx] are not universally performed following renal transplantation. In patients in whom protocol biopsies are performed, how best to manage subclinical rejection [SCR]…
2015 American Transplant Congress
Efficacy and Safety of Once-Daily Everolimus With Minimized Once-Daily Tacrolimus After Liver Transplantation
P. De Simone,¹ P. Carrai,¹ L. Coletti,¹ A. Precisi,² D. Campani,³ F. Filipponi.¹
¹Hepatobiliary Surgery and Liver Transplantation, University of Pisa Medical School Hospital, Pisa, Italy; ²Laboratory, University of Pisa Medical School Hospital, Pisa, Italy; ³Pathology, University of Pisa Medical School Hospital, Pisa, Italy.
Background: The everolimus (EVR) pharmacokinetic profile allows for its once daily (OD) administration. We tested the efficacy and safety of a combination schedule of OD-EVR…
2015 American Transplant Congress
Short-Term QOL After Live Liver Donation: A New York Center for Liver Transplantation (NYCLT) Report
D. LaPointe Rudow,¹ S. DeLair,² S. Florman,¹ J. Guarrera,³ M. Kinkhabwala,⁴ M. Orloff,⁵ Y. Wu,⁶ L. Teperman.⁷
¹Mount Sinai Medical Center, New York, NY; ²New York Center for Liver Transplantation, Albany, NY; ³New York Presbyterian Hosptial, New York, NY; ⁴Montefiore Medical Center, Bronx, NY; ⁵University of Rochester Medical Center, Rochester, NY; ⁶Westchester Medical Center, Valhala, NY; ⁷New York University Hospitals Center, New York, NY.
Introduction: LDLT is an option for selective patients, especially in regions with less opportunity for deceased donors. New York State (NYS) has the most LDLT…
2015 American Transplant Congress
Campath Induction With Triple Maintenance Therapy in African American Kidney Transplant Recipients: Less Infections But Worse Graft Survival
M. Gillespie, F. Rasetto, B. Masters, T. Sparkes, B. Ravichandran, M. Moss, A. Haririan.
University of Maryland Medical Center, Baltimore, MD.
Introduction:African American (AA) kidney transplant recipients (KTR) are at a higher risk for worse clinical outcomes vs non-AA. Strategies to improve outcomes in AA KTR…
2015 American Transplant Congress
Historical Comparison of Projected and Observed Liver Transplants
J. Pyke,¹ D. Schladt,¹ W. Kim,⁵ S. Leppke,¹ J. Lake,⁴ S. Gentry,^2,3 D. Segev,² A. Israni,¹ J. Snyder.¹
¹SRTR, Minneapolis Medical Research Foundation, Minneapolis, MN; ²Surgery, Johns Hopkins University School of Medicine, Baltimore, MD; ³Mathematics, US Naval Academy, Baltimore, MD; ⁴Medicine and Surgery, University of Minnesota Medical School, Minneapolis, MN; ⁵School of Medicine, Stanford University, Stanford, CA.
We aimed to compare liver transplant simulation projections to observed data before and after a major policy update. The current liver simulated allocation model (LSAM…
2015 American Transplant Congress
Do Induction Therapy, Patient-Level and Post-Operative Factors Impact Outcomes in Moderate to High Immunologic Risk Simultaneous Kidney-Pancreas Transplantation in the Era of Stringent HLA Cross-Matching?
V. Rohan, D. Taber, D. Taraskiewicz, S. Nadig, J. Mcgillicuddy, K. Chavin, P. Baliga, C. Bratton.
MUSC, Charleston, SC.
Background: Simultaneous kidney and pancreas transplantation (SPK) is a lifesaving procedure for patients with diabetes mellitus. The success of SPK is dependent upon minimization of…
2015 American Transplant Congress
Delayed Tacrolimus (TAC) to Rapamycin (RAPA) Conversion in Renal Transplant Recipients With DGF/SGF
A. Haririan,¹ D. Klassen,¹ M. Keshtkar,¹ C. Drachenberg,² T. Dowling,³ E. Ramos,¹ R. Ugarte,¹ C. Cangro,¹ M. Weir.¹
¹Medicine, University of Maryland, Baltimore, MD; ²Pathology, University of Maryland, Baltimore, MD; ³Pharmacy, University of Maryland, Baltimore, MD.
The role of conversion from TAC to RAPA early after kidney transplantation in patients with DGF/SGF in improving graft function and delaying chronic allograft dysfunction…
2015 American Transplant Congress
Epidemiology and Outcomes of Non Tuberculous Mycobacterial (NTM) Infections in Solid Organ Transplant (SOT) Recipients
I. George, C. Santos, M. Olsen, T. Bailey.
Infectious Diseases, Washington University School of Medicine, St. Louis, MO.
Background: NTM are uncommon causes of infection in SOT recipients but may cause significant morbidity and mortality.Methods: A retrospective cohort of all patients who underwent…