The Utility of Non-Invasive Intra Abdominal Pressure Monitoring After Pediatric Abdominal Organ Transplantation
1Pediatrics, Georgetown University School of Medicine, Washington, DC
2Georgetown Transplant Institute, MedStar-Georgetown University Hospital, Washington, DC
3Pediatrics, Pharmacology and Physiology, MedStar-Georgetown University Hospital, Washington, DC.
Meeting: 2015 American Transplant Congress
Abstract number: C289
Keywords: Liver transplantation, Outcome, Pediatric, Post-operative complications
Session Information
Session Name: Poster Session C: Late Breaking
Session Type: Poster Session
Date: Monday, May 4, 2015
Session Time: 5:30pm-6:30pm
Presentation Time: 5:30pm-6:30pm
Location: Exhibit Hall E
Intra abdominal pressure (IAP) is monitored in critically ill children because intra-abdominal hypertension (IAH) may be associated with renal dysfunction and adverse outcomes.
We retrospectively examined the incidence and clinical relevance of increased IAP, measured by the transurethral catheter method in 28 pediatric solid abdominal organ transplant recipients between 0-48 hours postoperatively from November 2011 to September 2013, by correlating IAP levels with mean blood pressure (MABP, mm Hg), abdominal perfusion pressure (APP), serum creatinine, urine output, graft and patient survival (at 1 year follow-up), hospital length of stay (LOS) and PICU LOS using Spearman's Coefficient. Isolated increases in IAP were classified as mild (10-14 cm H2O), moderate (15-20 cm) and severe (>20 cm of water) with or without organ dysfunction. Mean IAP between 0-8 hours postoperatively was 7.6 ± 0.7 (Mean ± SEM) and did not change significantly over the first 48 hrs. IAP was >10 cms H2O in 18/28 patients on one or more occasions. The peak IAP was 12.1 ± 0.9. Two cases of severe IAH were documented, who had lower MABP (67.2 ± 1.9), APP (53.4 ± 2.7), urine output (1.6 ± 0.36 ml/min) and greater Cr (0.5 ± 0.04) compared to patients with moderate and mild IAH. In summary, in our cohort, IAH did not affect graft or patient survival. Severe IAH, despite being infrequent, was associated with lower MABP, APP, urine output and worse renal function.
To cite this abstract in AMA style:
Harkin E, McLeod M, Khan K, Natarajan A. The Utility of Non-Invasive Intra Abdominal Pressure Monitoring After Pediatric Abdominal Organ Transplantation [abstract]. Am J Transplant. 2015; 15 (suppl 3). https://atcmeetingabstracts.com/abstract/the-utility-of-non-invasive-intra-abdominal-pressure-monitoring-after-pediatric-abdominal-organ-transplantation/. Accessed October 10, 2024.« Back to 2015 American Transplant Congress