Articles tagged "Methodology"

2020 American Transplant Congress
Patient-Informed Design of an Educational Website on Living Kidney Donation
M. Keller¹, R. Seibert¹, T. Feeley², L. Kayler¹
¹Erie County Medical Center, Buffalo, NY, ²University at Buffalo, SUNY, Buffalo, NY
*Purpose: Web-based education may be a powerful tool to support kidney patients’ learning about living kidney donation (LKD); however, websites that are not user-friendly can…
2020 American Transplant Congress
Mass Cytometry-Based Immunoprofiling as a Tool to Predict Rejection in a Large Cohort of Pediatric Transplant Recipients
M. Rao¹, J. T. Harden², M. Lapasaran², C. O. Esquivel³, O. M. Martinez², S. M. Krams²
¹Pediatrics, Stanford University, Palo Alto, CA, ²Stanford University School of Medicine, Stanford, CA, ³Surgery and Pediatrics, Stanford University School of Medicine, Stanford, CA
*Purpose: Rejection remains a serious problem in the pediatric transplant population. Early detection remains a challenge; furthermore, the changes in immune makeup which accompany rejection…
2020 American Transplant Congress
Improved Medication Safety Outcomes with a Mobile Health, Pharmacist-Led Intervention: Results of the TRANSAFE Rx Randomized Controlled Trial
H. Gonzales, J. Fleming, M. Gebregziabher, J. McGillicuddy, D. Taber
MUSC, Charleston, SC
*Purpose: Medication (med) safety events are a predominant cause of poor health outcomes, particularly within high-risk groups such as kidney transplant (KTX) recipients. The primary…
2020 American Transplant Congress
Quantifying Gender-Based Disparties in Liver Allocation: A Path Forward
B. A. Shelton¹, K. Olthoff², E. Pomfret³, K. A. Forde², D. Sawinski⁴, M. Gray¹, N. Ascher⁵, J. E. Locke¹
¹University of Alabama at Birmingham, Birmingham, AL, ²University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, ³University of Colorado School of Medicine, Denver, CO, ⁴University of Pennsylvania, Philadelphia, PA, ⁵University of California at San Francisco School of Medicine, San Francisco, CA
*Purpose: Differences in local organ supply and demand have introduced geographic inequities in the Model for End-stage Liver Disease (MELD) based liver allocation system prompting…
2020 American Transplant Congress
microPOTS: A New Single Cell Proteomic Method for Profiling Human Kidney Transplant Biopsy Tissue
T. Sigdel¹, P. Piehowski², S. Roy¹, J. Liberto¹, A. Schroeder¹, P. Rashmi¹, S. Sur¹, I. Damm¹, W. Qian², M. M. Sarwal¹
¹University of California San Francisco, San Francisco, CA, ²Pacific Northwest National Laboratory, Richland, WA
*Purpose: The purpose of this study was to interrogate acute rejection (AR) in the renal allograft at single cell level. Despite advances in single cell…
2020 American Transplant Congress
The Centers for Medicare and Medicaid Services’ Proposed Metrics for Recertification of Organ Procurement Organizations: Evaluation by the Scientific Registry of Transplant Recipients
J. Snyder¹, D. Musgrove¹, D. Zaun¹, A. Wey¹, N. Salkowski¹, J. Rosendale², A. Israni¹, R. Hirose³, B. Kasiske¹
¹SRTR, Minneapolis, MN, ²UNOS, Richmond, VA, ³Department of Surgery, Univ of California, San Francisco, San Francisco, CA
*Purpose: On December 23, 2019, the US Centers for Medicare and Medicaid Services proposed two new standards that organ procurement organizations (OPOs) must meet for…
2020 American Transplant Congress
Mass-Spectrometry Based Discovery of Tubular Injury Marker in Chronic Kidney Disease
J. Kim¹, D. Han¹, J. Jeong², J. Moon¹, S. Lee³, Y. Kim¹, K. Yoo⁴, D. Kim¹, Y. Kim¹, S. Yang¹
¹Seoul National University Hospital, Seoul, Korea, Republic of, ²Veterans Health Service Medical Center, Seoul, Korea, Republic of, ³Kangwon National University Hospital, Kangwon-do, Korea, Republic of, ⁴Ulsan National University Hospital, Ulsan, Korea, Republic of
*Purpose: Renal tubular injury and interstitial fibrosis are inevitable processes in the progression of chronic kidney disease (CKD). The purpose of this study is to…
2020 American Transplant Congress
Enumeration of Platelets by Flow Cytometry Reveals Human Erythrocyte Fragmentation During Pig Organ Xenoperfusion Studies
Z. Abady¹, K. M. Petitpas¹, L. Burdorf¹, S. G. Pratts¹, B. M. Cerel¹, S. Sendil², M. R. Connolly¹, W. Qin³, Y. Kan³, J. Layer³, M. Youd³, W. Westlin³, L. Yang³, R. N. Pierson III¹, A. M. Azimzadeh¹
¹Surgery, Massachusetts General Hospital and Harvard School of Medicine, Boston, MA, ²Surgery, University of Maryland School of Medicine, Baltimore, MD, ³eGenesis, Cambridge, MA
*Purpose: Human or baboon platelet sequestration and activation occurs during pig organ xenograft perfusion, although the mechanism remains poorly understood. To evaluate an apparent “rebound”…
2019 American Transplant Congress
Validation Of The Optimized Prediction Of Mortality (Opom) Machine Learning Model For Non-hepatocellular Carcinoma Candidates Awaiting Liver Transplant
L. Lau¹, X. Xie², F. Jia², P. D. Greig¹, T. C. Chan²
¹Multi-Organ Transplant, Department of Surgery, University of Toronto, Toronto, ON, Canada, ²Mechanical and Industrial Engineering, University of Toronto, Toronto, ON, Canada
*Purpose: Currently the Model for End-Stage Liver Disease (MELD) is used to rank candidates for liver transplant in many jurisdictions. However, MELD does not provide…
2019 American Transplant Congress
Creating Geographic Catchment Areas for Solid Organ Transplant Centers
K. Ross¹, R. Patzer², D. Axelrod³
¹Emory University, Emory Transplant Center, Georgetown, TX, ²Emory University, Emory Transplant Center, Georgetown, GA, ³Dept of Surgery, University of Iowa, Iowa City, IA
*Purpose: While measurement of transplant center performance has traditionally begun at listing, there is a significant population of potential candidates who may benefit from transplant…