2022 American Transplant Congress
Outcomes in Lung Transplant Recipients Switched from Tacrolimus to Cyclosporine Due to Hyperammonemia Early Post-Transplantation
Loyola University Medical Center, Chicago, IL
*Purpose: Assess the impact of switching from tacrolimus to cyclosporine due to hyperammonemia on outcomes at 1-year post-lung transplant.*Methods: A retrospective review of lung transplant…2022 American Transplant Congress
The Impact of Long-Term Exposure to Tacrolimus on Chronic Kidney Disease Following Lung Transplantation: A Retrospective Analysis from a Single Transplantation Center
*Purpose: Chronic kidney disease (CKD) is a progressive and irreversible complication in lung transplant patients who have received long-term treatment with tacrolimus. This study aimed…2022 American Transplant Congress
Safety and Efficacy of Peri-Vaccination Antimetabolite Hold to Augment Third SARS-CoV-2 Vaccine Dose Response in Lung Transplant Recipients
Johns Hopkins University School of Medicine, Baltimore, MD
*Purpose: Lung transplant recipients (LTRs) are less likely than other solid organ transplant recipients (SOTRs) to develop an antibody response to SARS-CoV-2 vaccination. Mycophenolate has…2022 American Transplant Congress
Angiotensin II-Regulated Proteins Production by Pulmonary Macrophages in Chronic Lung Allograft Dysfunction
*Purpose: Chronic lung allograft dysfunction (CLAD), characterized by fibrosis, is the most important cause of mortality after lung transplantation. CLAD mechanisms remain poorly understood and…2022 American Transplant Congress
Clinical Impact of a Modified Lung Allocation Score That Mitigates Selection Bias
*Purpose: The U.S. lung allocation system uses the Lung Allocation Score (LAS) to prioritize lung transplant candidates. Selection bias, induced by dependent censoring of waitlisted…2022 American Transplant Congress
Direct Central Ambulatory Venoarterial Extracorporeal Membrane Oxygenation and Double Lung Transplantation without Graft Reduction with Extreme Mediastinal Shift
*Purpose: Double Lung transplantation in the presence of extreme mediastinal shift can be technically challenging due to donor sizing and recipient factors.*Methods: We present the…2022 American Transplant Congress
Lung Transplant Recipients with Sars-cov2 Infection and Bnt162b2 Vaccination Induce Circulating Exosomes with Spike Protein S2 Capable of Inducing Immune Responses to Sars0-cov2 in Mice
1St. Joseph’s Hospital and Medical Center, Phoenix, AZ, 2Yale School of Medicine, New Haven, CT
*Purpose: Exosomes are small vesicles which are released by cells into body fluids. We have demonstrated the presence of circulating exosomes with viral antigens in…2022 American Transplant Congress
De Novo Donor-Specific Antibody Development with Mycophenolate versus Azathioprine in Lung Transplant Recipients
*Purpose: The effect of mycophenolate mofetil (MMF) or azathioprine (AZA) immunosuppression (ISN) regimens on de novo donor specific antibody (DSA) formation in lung transplant recipients…2022 American Transplant Congress
The Addition of Bortezomib to a Rituximab Based Antibody Mediated Rejection Treatment Protocol in Lung Transplant
Loyola University Medical Center, Maywood, IL
*Purpose: To evaluate the impact of antibody mediated rejection (AMR) treatment with rituximab combined with bortezomib vs. rituximab alone on patient survival, graft survival, and…2022 American Transplant Congress
Lung Transplantation For Covid-19: An International Registry
*Purpose: SARS-CoV-2 can result in a range of infections from asymptomatic disease to progressive COVID-19 and death. In some patients with COVID-19 Lung Disease (C19LD),…
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