2020 American Transplant Congress
Glucocorticoid-Induced Osteoporosis in Lung Transplant Patients
Department of Pharmacy, University of Chicago Medicine, Chicago, IL
*Purpose: Although vital for preventing rejection, glucocorticoids contribute to post-operative morbidity, including osteoporosis. The primary purpose of this study was to identify the occurrence of…2020 American Transplant Congress
Divergent Molecular Pathways Underlie the Evolution of Allograft Fibrosis in Two Mouse Models of Chronic Lung Allograft Dysfunction
*Purpose: Chronic lung allograft dysfunction (CLAD) after lung transplantation (LTx) is potentiated by activation of the innate immune system and occurs in two patterns: diffuse…2020 American Transplant Congress
Safety and Immunogenicity of Adjuvanted Recombinant Subunit Herpes Zoster Vaccine in Lung Transplant Recipients
1University Health Network, Toronto, ON, Canada, 2CDC, Atlanta, GA
*Purpose: The new adjuvanted subunit recombinant herpes zoster vaccine (RZV; Shingrix™) may have potential utility in transplant patients for the prevention of shingles, but there…2020 American Transplant Congress
Effects of Subnormothermic Ex Vivo Lung Perfusion on Inflammatory Injury in a Murine Lung Transplant Model
*Purpose: Ex vivo lung perfusion (EVLP) has emerged as a technique that safely preserve lungs prior to transplantation. Recent evidence demonstrates increased levels of inflammatory…2020 American Transplant Congress
Evaluation of the Mitra Microsampling Device for TTV Measurement in Human Whole Blood of Lung Transplant Recipients
*Purpose: The apathogenic Torque Teno Virus (TTV) is highly prevalent among solid organ transplant recipients and mirrors the immunocompetence of its host. qPCR based measurement…2020 American Transplant Congress
Improved Kidney Function Post Lung Transplant with Intravenous Tacrolimus Avoidance
*Purpose: Tacrolimus (TAC) poses a dose-dependent risk of acute kidney injury (AKI) as well as chronic kidney disease (CKD) post-transplant. In 2017, our institution’s lung…2020 American Transplant Congress
Bilateral Lung Transplantation Combined with Cardiac Correction in Treatment of Severe Pulmonary Arterial Hypertension Complicated with Eisenmenger Syndrome in Puerpera, a Feasible Strategy for Future?
*Purpose: Though pregnancy is not recommended for patients with pulmonary arterial hypertension (PAH) in current guidelines, some patients do stick to parturition due to varies…2020 American Transplant Congress
The Impact of Thy1 Expression of Fibroblast for Chronic Lung Allograft Dysfunction
*Purpose: Chronic lung allograft dysfunction (CLAD) result from excessive immune activation and excessive collagen deposition by fibroblasts within the lung parenchyma or airway.Bronchiolitis obliterans (OB)…2020 American Transplant Congress
A Survey of Lung Transplant Recipient Attitudes and Beliefs on Accepting an Organ That Was Positive for Hepatitis C Virus
*Purpose: Recent data show that organs from donors who are HCV positive (+ve) can be safely transplanted into HCV negative recipients. We conducted a survey…2020 American Transplant Congress
Use of 16S Sequencing to Reveal Potential Respiratory Pathogens in Lung Transplant Recipients
*Purpose: Respiratory infections are common after lung transplant and contribute to mortality and allograft failure. 16S ribosomal RNA (rRNA) gene sequencing could facilitate diagnosis of…
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