Articles tagged "Lung transplantation"

2022 American Transplant Congress
Inhalation Alone versus Inhalation Plus Intravenous Colistin for Multidrug-Resistant Gram-Negative Bacterial Infection After Lung Transplantation
H. Kim¹, Y. Yang¹, A. Woo², S. Jeong³, S. Kim², J. Lee¹, M. Park², H. Paik¹
¹Department of thoracic and cardiovascular surgery, Yonsei University College of medicine, Seoul, Korea, Republic of, ²Division of Pulmonology, Department of Internal Medicine, Yonsei University College of medicine, Seoul, Korea, Republic of, ³Division of Infectious Disease, Department of Internal Medicine, Yonsei University College of medicine, Seoul, Korea, Republic of
*Purpose: After lung transplantation, patients are exposed to the risk of various infections accounting for morbidity and mortality. Multidrug-resistant gram-negative (MDR-GN) bacteria are emerging pathogen.…
2022 American Transplant Congress
Surveillance with Allosure for Allograft Rejection and Infection in Lung Transplant
M. M. Botros¹, N. Sulejmani², B. F. Reader³, B. C. Keller¹
¹Pulmonary, Critical Care & Sleep Medicine, The Ohio State University, Columbus, OH, ²Medical Affairs, CareDx, South San Francisco, CA, ³Division of Transplant Surgery, The Ohio State University, Columbus, OH
*Purpose: Measurement of plasma donor-derived cell-free DNA (dd-cfDNA; AlloSure, CareDx) has been shown to be a useful non-invasive diagnostic test for injury and infection after…
2022 American Transplant Congress
Perioperative Cardiovascular Outcomes of Pre-Transplant ECMO in Recipients of Lung Transplant
F. Anjum¹, R. Munshi², A. M. Courtwright¹, M. M. Crespo¹, J. C. Salgado¹, J. D. Christie¹, V. N. Ahya¹, N. Patel¹, D. Hadjiliadis¹, E. Clausen¹, M. Cevasco³, E. E. Cantu³, C. A. Bermudez³, J. M. Diamond¹
¹Pulmonary and Critical Care, University of Pennsylvania, Philadelphia, PA, ²Nassau University Medical Center, East Meadow, NY, ³Cardiovascular Surgery, University of Pennsylvania, Philadelphia, PA
*Purpose: Use of extracorporeal membrane oxygenation (ECMO) as a bridge to lung transplant (BTT) has increased over time. While similar one-year and overall survival has…
2022 American Transplant Congress
Variability In Plasma Donor-derived Cell-free DNA Levels With CLAD More Than 5-years After Lung Transplantation: Pilot Data
D. Levine¹, D. Ross²
¹Department of Medicine, University of Texas, San Antonio, San Antonio, TX, ²Natera, Inc., Ausin, TX
*Purpose: Donor-derived cell-free DNA (dd-cfDNA) has been clinically validated for detection of acute rejection (AR) in lung transplant (LT) although studies have typically focused on…
2022 American Transplant Congress
The SHELTER Trial of Transplanting Donor Hepatitis C Virus RNA+ Lungs Into Uninfected Recipients
V. Potluri¹, P. Reese¹, S. Prenner¹, H. Mentch¹, D. Goldberg², T. Claridge¹, J. Smith¹, C. Gentile¹, V. Van Deerlin¹, R. Reddy¹, T. Fallah¹, C. Bermudez¹, M. Crespo¹, J. Diamond¹
¹University of Pennsylvania, Philadelphia, PA, ²University of Miami, Miami, FL
*Purpose: The advent of direct acting antiviral therapy has motivated centers to transplant lungs from donors with hepatitis C virus infection (HCV-RNA+) into uninfected recipients.…
2022 American Transplant Congress
Transbronchial Cryobiopsy vs Conventional Forceps Biopsy in Lung Transplant Recipients Multicenter Study
M. Svorcova¹, J. Vachtenheim¹, J. Havlin¹, P. Jakubec², D. Rakita³, J. Balko⁴, J. Simonek¹, J. Kolarik¹, J. Pozniak¹, R. Lischke¹
¹3rd Surgery Department, 1st Faculty of Medicine, Charles University in Prague and Motol University, National Lung Transplant Program Prague, Prague, Czech Republic, ²Department of respiratory disease and tuberculosis, University Hospital Olomouc, Olomouc, Czech Republic, ³Department of pneumology, 2nd Faculty of Medicine, Charles University in Prague and Motol University, Prague, Czech Republic, ⁴Department of Pathology and Molecular Medicine, 2nd Faculty of Medicine, Charles University in Prague and Motol University, Prague, Czech Republic
*Purpose: Transbronchial biopsy is considered the gold standard in the diagnosis of acute cellular rejection after lung transplantation. There still remains the discussion in conventional…
2022 American Transplant Congress
Simultaneous Lung and Kidney Transplant in a Young Patient with COVID-19
M. Bitar¹, J. G. Youssef², S. Yau², A. Goodarzi², G. Youssef³
¹Houston Methodist Academic Pulmonary Medicine, Houston Methodist Hospital, Houston, TX, ²Houston Methodist Pulmonary Transplant Center, Houston Methodist Hospital, Houston, TX, ³Department of Lymphoma and Myeloma, MD Anderson Cancer Center, Houston, TX
*Purpose: Lung transplant is the last resort for COVID-19 refractory ARDS. Dual organ transplant is seen as a relative contraindication at many institutions. We describe…
2022 American Transplant Congress
CD31⁺ Extracellular Vesicles in Ex Vivo Lung Perfusion Are Associated with Unsuitability for Transplant
G. C. Madu¹, S. Moshkelgosha², A. Chruscinski³, A. Sage², M. Cypel², S. Keshavjee², S. Juvet²
¹Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada, ²University Health Network, Toronto, ON, Canada, ³Multi-Organ Transplantation, University Health Network, Toronto, ON, Canada
*Purpose: Primary graft dysfunction (PGD) is an important cause of morbidity and mortality following lung transplantation and results in part from injuries sustained in the…
2022 American Transplant Congress
Longitudinal Analysis of the Lung Microbiome and Immune Status in Lung Transplant Recipients
Y. Zhao, P. Zhang, Y. Su, Y. Zhu, L. Shen
Shanghai Pulmonary Hospital, Shanghai, China
*Purpose: The dynamic remodeling of lung flora structure and the association between microbial community dynamics and immune status after lung transplantation (LTx) remain unclear.*Methods: Fourteen…
2022 American Transplant Congress
Lung Transplantation Outcomes in Recipients Living with HIV in the United States
J. M. Czeresnia¹, S. Madan², M. M. Abbasi³, V. Hemmige¹
¹Department of Medicine - Division of Infectious Diseases, Montefiore Medical Center, Bronx, NY, ²Department of Medicine - Division of Cardiology, Montefiore Medical Center, Bronx, NY, ³Department of Surgery - Division of Cardiovascular and Thoracic Surgery, Montefiore Medical Center, Bronx, NY
*Purpose: To compare outcomes of lung transplantation in HIV-positive and HIV-negative recipients in the United States.*Methods: A national transplant database (UNOS/SRTR) was queried for cases…