Articles tagged "Lung transplantation"

2022 American Transplant Congress
Simultaneous Lung and Kidney Transplant in a Young Patient with COVID-19
M. Bitar¹, J. G. Youssef², S. Yau², A. Goodarzi², G. Youssef³
¹Houston Methodist Academic Pulmonary Medicine, Houston Methodist Hospital, Houston, TX, ²Houston Methodist Pulmonary Transplant Center, Houston Methodist Hospital, Houston, TX, ³Department of Lymphoma and Myeloma, MD Anderson Cancer Center, Houston, TX
*Purpose: Lung transplant is the last resort for COVID-19 refractory ARDS. Dual organ transplant is seen as a relative contraindication at many institutions. We describe…
2022 American Transplant Congress
CD31⁺ Extracellular Vesicles in Ex Vivo Lung Perfusion Are Associated with Unsuitability for Transplant
G. C. Madu¹, S. Moshkelgosha², A. Chruscinski³, A. Sage², M. Cypel², S. Keshavjee², S. Juvet²
¹Temerty Faculty of Medicine, University of Toronto, Toronto, ON, Canada, ²University Health Network, Toronto, ON, Canada, ³Multi-Organ Transplantation, University Health Network, Toronto, ON, Canada
*Purpose: Primary graft dysfunction (PGD) is an important cause of morbidity and mortality following lung transplantation and results in part from injuries sustained in the…
2022 American Transplant Congress
Longitudinal Analysis of the Lung Microbiome and Immune Status in Lung Transplant Recipients
Y. Zhao, P. Zhang, Y. Su, Y. Zhu, L. Shen
Shanghai Pulmonary Hospital, Shanghai, China
*Purpose: The dynamic remodeling of lung flora structure and the association between microbial community dynamics and immune status after lung transplantation (LTx) remain unclear.*Methods: Fourteen…
2022 American Transplant Congress
Lung Transplantation Outcomes in Recipients Living with HIV in the United States
J. M. Czeresnia¹, S. Madan², M. M. Abbasi³, V. Hemmige¹
¹Department of Medicine - Division of Infectious Diseases, Montefiore Medical Center, Bronx, NY, ²Department of Medicine - Division of Cardiology, Montefiore Medical Center, Bronx, NY, ³Department of Surgery - Division of Cardiovascular and Thoracic Surgery, Montefiore Medical Center, Bronx, NY
*Purpose: To compare outcomes of lung transplantation in HIV-positive and HIV-negative recipients in the United States.*Methods: A national transplant database (UNOS/SRTR) was queried for cases…
2022 American Transplant Congress
Impact of Belatacept on Clinical Outcomes in Lung Transplant Patients with Antibody-Mediated Rejection
L. Zaffiri, R. Hallak, S. Leonard, M. Neely, A. Hulber, H. Berry, K. A. Young, J. M. Reynolds
Duke University, Durham, NC
*Purpose: Antibody-mediated rejection (AMR) is cause of significant morbidity and mortality in lung transplant recipients (LTRs). An optimal therapeutic regimen is still lacking. Recent evidence…
2022 American Transplant Congress
The Impact of Tacrolimus Trough Variability on Acute Rejection Following Lung Transplantation
K. Evans¹, K. Beermann¹, H. Lee², M. Harris¹, C. W. Frankel³, H. Berry¹, H. Ali³
¹Pharmacy, Duke Health, Durham, NC, ²Biostatistics and Bioinformatics, Duke University, Durham, NC, ³Pulmonary, Allergy, and Critical Care, Duke Health, Durham, NC
*Purpose: This study aimed to evaluate the association of tacrolimus coefficient of variation (CV) with biopsy-proven acute cellular rejection in the first year following lung…
2022 American Transplant Congress
More Than Just Drain Pipes, Pulmonary Lymphatics Play a Pivotal Role in the Development of Bronchiolitis Obliterans Syndrome
L. Wang¹, R. Han², H. Outtz Reed³, W. W. Hancock²
¹Childrens Hospital of Phila, Philadelphia, PA, ²Children's Hospital of Philadelphia, Philadelphia, PA, ³Weill Cornell, New York, NY
*Purpose: Chronic allograft dysfunction (CLAD) remains a major determinant of the generally poor long-term outcome of lung transplantation compared to that of other solid organ…
2022 American Transplant Congress
Risk Factors for Extubation Failure Post- Lung Transplantation
A. J. Trindade¹, W. D. Gannon¹, A. G. Dragnich¹, G. Dahlberg¹, C. T. Demarest², E. S. Lambright², K. A. McPherson¹, S. G. Norfolk¹, C. M. Shaver¹, I. M. Robbins¹, M. Bacchetta²
¹Allergy, Pulmonary and Critical Care Medicine, Vanderbilt University Medical Center, Nashville, TN, ²Thoracic Surgery, Vanderbilt University Medical Center, Nashville, TN
*Purpose: Extubation delays following lung transplantation can result in delirium, deconditioning, infections, and increased hospital length of stay. Risk stratifying patients for extubation failure may…
2022 American Transplant Congress
Incidence and Laterality of Pulmonary Emboli in Single Lung Transplant Recipients
F. Pyarali¹, J. Thomas², A. Peiris², R. Rampolla¹
¹Department of Pulmonary and Critical Care, Cedars Sinai Medical Center, Los Angeles, CA, ²Smidt Heart Institute, Cedars Sinai Medical Center, Los Angeles, CA
*Purpose: Lung transplantation surgery increases the risk of pulmonary embolism (PE), with an incidence described between 6% to 27%, based on data from 15 years…
2022 American Transplant Congress
Evaluation of Crushed Posaconazole Delayed Release Tablets in Lung Transplant Recipients
R. Gordon¹, K. Dewey¹, R. Jariwala¹, B. Yen¹, J. Kukreja², S. Hays², J. Singer², R. Florez¹
¹Department of Clinical Pharmacy, University of California, San Francisco, San Francisco, CA, ²University of California, San Francisco, San Francisco, CA
*Purpose: We hypothesized that crushed posaconazole delayed release (POSA DR) tablets can reach therapeutic levels in lung transplant recipients who are at risk for invasive…