Articles tagged "Liver"

2021 American Transplant Congress
Black Patients with Cirrhosis Have Longer Length of Stay and Higher Mortality When Hospitalized
A. Thomas¹, D. Simpson², D. P. Ladner², R. Berkowitz²
¹ACS Clinical Scholar, Chicago, IL, ²Transplant Surgery, Northwestern University Feinberg School of Medicine, Chicago, IL
*Purpose: Black patients with cirrhosis have been shown to have higher liver-related mortality compared to White patients. However, little knowledge exists about racial differences related…
2021 American Transplant Congress
The Inflammatory Response in the Context of Tissue Injury: Roles of Tyro3, Axl, and Mer (TAM) Receptor Tyrosine Kinases in Liver Ischemia/reperfusion Injury
J. Zhang¹, H. Zhang¹, M. Ni², R. Busuttil¹, J. Kupiec-Weglinski¹, Y. Zhai¹
¹Dumont-UCLA Transplant Center, Los Angeles, CA, ²Liver Suyrgery, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China
*Purpose: Although the inflammatory response in liver ischemia reperfusion injury has been studied extensively, how the context of tissue injury (presence of necrotic/apoptotic cells) regulates…
2021 American Transplant Congress
Influence of Controlled Donation After Circulatory Death (cdcd) on Waiting List Mortalityfor Liver Transplantation in the Last 10 Years: The Spanish Experience
F. Alconchel, M. Royo-Villanova, J. Moya, L. Martínez-Alarcón, J. Zambudio, P. Cascales-Campos, T. Nicolás, R. Robles, F. Sánchez-Bueno, J. Pons, J. Rodríguez, A. Ríos, J. Fernández, P. Ramírez
University Hospital Virgen Arrixaca (IMIB-Arrixaca), Murcia, Spain
*Purpose: Controlled donation after circulatory death (cDCD) provides one third of liver donors in Spain nowadays. The aim of our work is to evaluate the…
2021 American Transplant Congress
Early Review of Liver Acuity Circles Allocation
S. Noreen¹, J. Heimbach², J. Pomposelli³, M. Cafarella¹, J. Trotter⁴
¹UNOS, Richmond, VA, ²Mayo Clinic, Rochester, MN, ³UCHealth, Aurora, CO, ⁴BSWHealth, Dallas, TX
*Purpose: Acuity circles (AC) allocation was implemented on February 4, 2020, followed shortly by the declaration of national emergency for COVID-19. The goal of this…
2021 American Transplant Congress
A Patient-Centered Perspective on Progress in Transplantation
B. Hickner¹, N. Galvan², R. Cotton², C. O'Mahony², J. Goss², A. Rana²
¹Department of Student Affairs, Baylor College of Medicine, Houston, TX, ²Department of Surgery, Baylor College of Medicine, Houston, TX
*Purpose: This study aimed to provide a patient-centered perspective on change in transplantation outcomes through analysis of intent-to-treat survival, which accounted for donor shortages by…
2021 American Transplant Congress
Eosinophils Attenuate Hepatic Ischemia Reperfusion Injury in Mice Through St2-Dependent Il-13 Production
Y. Yang, Y. Wang, M. Wang, J. Jeong, L. Xu, Y. Wen, C. Emontzpohl, W. Dar, C. Ju
Department of Anesthesiology, McGovern Medical School University of Texas Health Science Center at Houston, Houston, TX
*Purpose: The purpose is to investigate the functional role of eosinophils during hepatic ischemia and reperfusion injury (IRI).*Methods: Mice with antibody-induced eosinophil depletion and two…
2021 American Transplant Congress
Glycogen Synthase Kinase 3 Beta Regulates Distinctive Macrophage Subsets in the Activation and Resolution of Liver Ischemia Reperfusion Injury
H. Zhang¹, M. Ni², J. Zhang¹, H. Wang², R. Busuttil¹, J. Kupiec-Weglinski¹, Y. Zhai¹
¹Dumont-UCLA Transplant Center, Los Angeles, CA, ²The First Affiliated Hospital of Nanjing Medical University, Nanjing, China
*Purpose: Glycogen synthase kinase 3β (Gsk3β) differentially regulates pro- and anti-inflammatory programs in macrophages upon TLR stimulations. We have documented in a murine liver partial…
2021 American Transplant Congress
Allocation Changes and Covid Effect on Waiting Time for Liver Transplantation
L. Dageforde¹, Q. Yuan², N. Elias¹
¹Division of Transplantation, Massachusetts General Hospital, Boston, MA, ²Organ Transplant Institute, 8th Medical Center, Chinese PLA General Hospital, Beijing, China
*Purpose: On April 30, 2019 the National Liver Review Board (NLRB) was implemented and patients meeting criteria for hepatocellular carcinoma exception points received a score…
2021 American Transplant Congress
White, Older Men Are Less Affected by the Changes of the Covid-19 Pandemic
R. J. Berkowitz, A. Daud, S. Brietigam, T. S. Taylor, J. Carter, M. A. Callegari, B. Borja-Cacho, J. C. Caicedo, D. Simpson, D. P. Ladner
Surgery, Northwestern Medicine, Chicago, IL
*Purpose: This study explores quality of life and lifestyle changes due to the COVID-19 pandemic among pre- and post- liver (LT) and kidney (KT) transplant…
2021 American Transplant Congress
The Evolution of the National Liver Review Board
S. Noreen¹, J. Trotter², J. Pomposelli³, M. Cafarella¹, J. Heimbach⁴
¹UNOS, Richmond, VA, ²BSWHealth, Dallas, TX, ³UCHealth, Aurora, CO, ⁴Mayo Clinic, Rochester, MN
*Purpose: The National Liver Review Board (NLRB) was implemented 5/14/2019, establishing a national structure for liver exceptions comprised of three specialty review boards and a…