Articles tagged "Liver"

2021 American Transplant Congress
Is Low Systemic Fibrinolytic Activity During the Anhepatic Phase Liver Transplant Surgery Associate with the Dreaded Post-Operative Complication of Hepatic Artery Thrombosis?
H. B. Moore¹, Y. Bababekov¹, J. Pomposelli¹, T. Ferrell¹, F. Azam¹, M. Adams², D. Yoeli¹, R. Choudhury¹, M. Wachs², E. Pomfret¹, T. Nydam¹
¹University of Colorado, Aurora, CO, ²Childrens Hospital Colorado, Aurora, CO
*Purpose: Removal of the native liver during transplantation results in impaired clearance of clot degrading proteins and activation of fibrinolysis as appreciated by Starzl in…
2021 American Transplant Congress
Benign Pneumatosis Intestinalis with Pneumoperitoneum in the Immunocompromised Patient: Three Cases
A. Mohamed, K. Delvecchio, T. Kitajima, M. Rizzari, K. Collins, A. Yoshida, S. Nagai, J. Denny, M. Abouljoud
Department of Transplant and Hepatobiliary Surgery, Henry Ford Hospital, Detroit, MI
*Purpose: Isolated pneumatosis intestinalis after solid organ transplantation, as well as its surgical management in appropriate clinical context, is a well described entity. The management…
2021 American Transplant Congress
A Patient-Centered Perspective on Progress in Transplantation
B. Hickner¹, N. Galvan², R. Cotton², C. O'Mahony², J. Goss², A. Rana²
¹Department of Student Affairs, Baylor College of Medicine, Houston, TX, ²Department of Surgery, Baylor College of Medicine, Houston, TX
*Purpose: This study aimed to provide a patient-centered perspective on change in transplantation outcomes through analysis of intent-to-treat survival, which accounted for donor shortages by…
2021 American Transplant Congress
Eosinophils Attenuate Hepatic Ischemia Reperfusion Injury in Mice Through St2-Dependent Il-13 Production
Y. Yang, Y. Wang, M. Wang, J. Jeong, L. Xu, Y. Wen, C. Emontzpohl, W. Dar, C. Ju
Department of Anesthesiology, McGovern Medical School University of Texas Health Science Center at Houston, Houston, TX
*Purpose: The purpose is to investigate the functional role of eosinophils during hepatic ischemia and reperfusion injury (IRI).*Methods: Mice with antibody-induced eosinophil depletion and two…
2021 American Transplant Congress
Glycogen Synthase Kinase 3 Beta Regulates Distinctive Macrophage Subsets in the Activation and Resolution of Liver Ischemia Reperfusion Injury
H. Zhang¹, M. Ni², J. Zhang¹, H. Wang², R. Busuttil¹, J. Kupiec-Weglinski¹, Y. Zhai¹
¹Dumont-UCLA Transplant Center, Los Angeles, CA, ²The First Affiliated Hospital of Nanjing Medical University, Nanjing, China
*Purpose: Glycogen synthase kinase 3β (Gsk3β) differentially regulates pro- and anti-inflammatory programs in macrophages upon TLR stimulations. We have documented in a murine liver partial…
2021 American Transplant Congress
Influence of Controlled Donation After Circulatory Death (cdcd) on Waiting List Mortalityfor Liver Transplantation in the Last 10 Years: The Spanish Experience
F. Alconchel, M. Royo-Villanova, J. Moya, L. Martínez-Alarcón, J. Zambudio, P. Cascales-Campos, T. Nicolás, R. Robles, F. Sánchez-Bueno, J. Pons, J. Rodríguez, A. Ríos, J. Fernández, P. Ramírez
University Hospital Virgen Arrixaca (IMIB-Arrixaca), Murcia, Spain
*Purpose: Controlled donation after circulatory death (cDCD) provides one third of liver donors in Spain nowadays. The aim of our work is to evaluate the…
2021 American Transplant Congress
Early Review of Liver Acuity Circles Allocation
S. Noreen¹, J. Heimbach², J. Pomposelli³, M. Cafarella¹, J. Trotter⁴
¹UNOS, Richmond, VA, ²Mayo Clinic, Rochester, MN, ³UCHealth, Aurora, CO, ⁴BSWHealth, Dallas, TX
*Purpose: Acuity circles (AC) allocation was implemented on February 4, 2020, followed shortly by the declaration of national emergency for COVID-19. The goal of this…
2021 American Transplant Congress
The Evolution of the National Liver Review Board
S. Noreen¹, J. Trotter², J. Pomposelli³, M. Cafarella¹, J. Heimbach⁴
¹UNOS, Richmond, VA, ²BSWHealth, Dallas, TX, ³UCHealth, Aurora, CO, ⁴Mayo Clinic, Rochester, MN
*Purpose: The National Liver Review Board (NLRB) was implemented 5/14/2019, establishing a national structure for liver exceptions comprised of three specialty review boards and a…
2021 American Transplant Congress
Cellular Landscape of Steatotic Livers Revealed by Single-nuclei Rna Sequencing
C. Kuscu¹, C. Kuscu¹, A. Shetty², E. Bardhi³, T. Rousselle⁴, J. Eason¹, M. Sraj⁵, D. Maluf⁶, V. Mas⁴
¹Surgery, James D Eason Transplant Institute, Memphis, TN, ²University of Maryland, Institute for Genome Sciences, Baltimore, MD, ³Program in Transplantation - University of Maryland, Baltimore, MD, ⁴Surgery, Division of Surgical Science, Baltimore, MD, ⁵Surgery, University of Maryland, Baltimore, MD, ⁶Surgery, Program in Transplantation - University of Maryland, Baltimore, MD
*Purpose: Hepatic IRI represents a barrier to the use of available organs for transplant, particularly fatty livers. We aimed to discern the cellular subsets and…
2021 American Transplant Congress
“A New Lease on Life”: Patient Perceptions After Early Liver Transplantation for Alcohol-Related Liver Disease
R. Greenberg, G. Punchhi, H. Sung, K. Gianaris, M. Krach, K. Herrick-Reynolds, P. Chen, M. Levan, J. Garonzik Wang, A. Cameron
Johns Hopkins, Baltimore, MD
*Purpose: At some centers, alcohol-related liver disease (ARLD) patients, who are unlikely to survive six months without a liver transplant (LT), are selected to receive…