Articles tagged "Liver transplantation"

2021 American Transplant Congress
Liver Simulated Allocation Model (LSAM) of a Height-Based Policy Change to Improve Sex Disparity in Liver Transplantation (LT)
S. Bernards¹, E. Lee¹, N. Leung², H. Zhao², M. Akan³, M. Sarkar¹, S. Tayur³, N. Mehta¹
¹UCSF, SF, CA, ²City U, HK, Hong Kong, ³CMU, Pittsburgh, PA
*Purpose: Since the introduction of the MELD-based allocation system, women are now 30% less likely than men to undergo LT and have 20% higher waitlist…
2021 American Transplant Congress
Patient Feedback of a Patient and Family Decision Support Tool for Liver Organ Offer Decisions
C. Schaffhausen¹, S. Chu², M. Bruin³, S. Chinnakotla³, J. Lake³, A. Israni⁴
¹Hennepin Healthcare Research Institute, Minneapolis, MN, ²University of Minnesota (UMN), Minneapolis, MN, ³UMN, Minneapolis, MN, ⁴Hennepin Healthcare, UMN, Minneapolis, MN
*Purpose: For liver transplant candidates on the waiting list, deciding to accept a donor organ with known or potential risk factors can be stressful and…
2021 American Transplant Congress
Outcomes of Patients Referred for Liver Transplant Evaluation
E. Solomon¹, M. Waykar², K. Robichaux³, J. Buggs⁴, A. Kumar¹, N. Kemmer⁵
¹Morsani College of Medicine, University of South Florida, Tampa, FL, ²Honors College, University of Tampa, Tampa, FL, ³Honors College, University of South Florida, Tampa, FL, ⁴Transplant Surgery, Tampa General Hospital, Tampa, FL, ⁵Transplant Hepatology, Tampa General Hospital, Tampa, FL
*Purpose: National demand for liver transplants is increasing steadily, with 8,896 liver transplants performed in the USA in 2019, a 7.8% increase from 2018. The…
2021 American Transplant Congress
Liver Transplantation for Unresectable Colorectal Cancer Liver Metastases: A Multicenter Experience
L. I. Ruffolo¹, K. Sasaki², K. Tomiyama¹, A. Nair¹, M. Orloff¹, B. Al-Judaibi³, M. Levstik³, M. Laryea³, K. Dokus¹, J. Errigo¹, A. Moro², C. Quintini², K. Hashimoto², M. Fujiki², K. Menon², C. Kwon², T. Diago Uso², R. Hernandez-Alejandro¹, F. Aucejo²
¹Surgery, University of Rochester Medical Center, Rochester, NY, ²Surgery, The Cleveland Clinic Foundation, Cleveland, OH, ³Transplant Hepatology, University of Rochester Medical Center, Rochester, NY
*Purpose: Colorectal cancer is the third leading cause of cancer related death, unfortunately 50% of patients will develop colorectal liver metastases (CRLM), and a minority…
2021 American Transplant Congress
Impact of Graft Quality on Patient Survival in Sick Patients
G. Handing¹, S. Keeling¹, C. Christmann¹, N. Galvan², C. O’Mahony², J. Goss², R. Cotton², A. Rana²
¹School of Medicine, Baylor College of Medicine, Houston, TX, ²Michael E DeBakey Department of Surgery, Division of Abdominal Transplant, Houston, TX
*Purpose: It is widely accepted in the literature that patients who have a Model for End Stage Liver Disease (MELD) Score greater than 30 incur…
2021 American Transplant Congress
Outcomes After Liver Transplantation With Steatotic Grafts: Redefining Acceptable Cutoffs for Moderately Steatotic Grafts
B. L. Da¹, J. Satiya², R. P. Heda³, Y. Jiang⁴, L. Lau⁵, A. Fahmy¹, A. Winnick¹, N. Roth¹, E. Grodstein¹, P. J. Thuluvath⁶, A. K. Singal⁷, T. D. Schiano⁸, L. W. Teperman¹, S. K. Satapathy¹
¹Liver Disease, Northwell Health, Manhasset, NY, ²Beth Israel Deaconess Medical Center, Boston, MA, ³Tulane Medical Center, Memphis, TN, ⁴The University of Memphis, Memphis, TN, ⁵Northwell Health, Manhasset, NY, ⁶University of Maryland School of Medicine, Baltimore, MD, ⁷Liver Disease, Avera McKenna University Health Center and Transplant Institute, Manhasset, NY, ⁸Icahn School of Medicine at Mount Sinai, New York City, NY
*Purpose: Graft macro-steatosis can predispose to worse graft survival. Our objective was to redefine acceptable cutoffs for graft steatosis using the national database.*Methods: Data of…
2021 American Transplant Congress
Neutrophil Extracellular Trap-induced Thrombotic Microangiopathy in Steatotic Mouse Recipients Impacts Liver Transplant Outcomes
H. Hirao, H. Kojima, K. Kadono, K. J. Dery, D. G. Farmer, F. M. Kaldas, J. W. Kupiec-Weglinski
UCLA Medical Center, Los Angeles, CA
*Purpose: Nonalcoholic steatohepatitis (NASH) is an emerging global epidemic projected to become the leading indication for liver transplantation (LT). Although recent studies focus on the…
2021 American Transplant Congress
Neutrophil CEACAM1 Induces Hepatic Autophagy and Shapes Innate-adaptive Immune Response in Liver Transplantation: From Mouse-to-human
H. Hirao¹, H. Kojima¹, K. Kadono¹, K. J. Dery¹, K. Nakamura², D. G. Farmer¹, F. M. Kaldas¹, J. W. Kupiec-Weglinski¹
¹Surgery, Dumont-UCLA Transplant Center, Los Angeles, CA, ²Surgery, Kyoto University, Kyoto, Japan
*Purpose: Although CEACAM1 (CC1; carcinoembryonic antigen-related cell adhesion molecule 1; CD66a) regulates innate-adaptive immunity, its role in orthotopic liver transplantation (OLT) remains unknown. CC1 expresses…
2021 American Transplant Congress
Analyzing the Impact of Covid-19 in the Hospitalized Cohort of Liver Transplant Recipients: An Early Systematic Review and Meta-Analysis
J. Kumar¹, I. Reccia², P. Bachul¹, D. DiSabato,¹, R. Barth¹, J. Fung¹, T. Baker¹, P. Witkowski¹
¹University of Chicago, Chicago, IL, ²Imperial College, London, United Kingdom
*Purpose: To determine pooled prevalence of outcomes among hospitalized liver transplant recipients with COVID-19 through meta-analysis.*Methods: A database search was completed between Dec1, 2019-Nov15, 2020,…
2021 American Transplant Congress
The Combined Effects of Simultaneous Portal Vein Thrombosis and Renal Dysfunction in Liver Transplant Recipients
M. Molinari¹, C. F. Carillo², D. Dongling¹, D. Jorgensen¹, S. Dharmayan¹, C. Kaltenmeier¹, H. Liu¹, J. Behari¹, V. Rachakonda¹, S. Ganesh¹, C. Hughes¹, A. Tevar¹, H. Al Harakeh¹, B. Emmanuel¹, A. Humar¹, R. Bataller¹
¹University of Pittsburgh Medical Centre, Pittsburgh, PA, ²Medicine, University of Pittsburgh Medical Centre, Pittsburgh, PA
*Purpose: Simultaneous portal vein thrombosis (PVT) and renal dysfunction (RD) have unknown effects after liver transplant (LT). We analyzed the outcomes of patients with simultaneous…