Articles tagged "Liver transplantation"

2020 American Transplant Congress
Younger Age is Associated with Improved Survival in Patients Undergoing Liver Transplantation Alone for Metastatic Neuroendocrine Tumors
R. Gedaly, D. Valvi, X. Mei, M. Gupta, M. Shah, A. Ancheta, F. Marti
University of Kentucky, Lexington, KY
*Purpose: Neuroendocrine tumor (NET) metastases are a major cause of morbidity and mortality. The role of liver transplantation to treat unresectable metastases from NET is…
2020 American Transplant Congress
Health-Related Quality of Life after Anonymous Nondirected Living Liver Donation: A Multi-Center, North American Collaboration
M. H. Raza¹, W. E. Jackson², A. Dell³, L. Ding⁴, J. Shapiro³, E. A. Pomfret⁵, Y. Genyk⁶, L. Sher⁶, J. Emamaullee⁶
¹Keck School of Medicine of USC, Los Angeles, CA, ²Gastroenterology, University of Colorado, Aurora, CO, ³Surgery, University of Alberta, Edmonton, AB, Canada, ⁴Preventive Medicine, University of Southern California, Los Angeles, CA, ⁵Surgery, University of Colorado, Aurora, CO, ⁶Surgery, University of Southern California, Los Angeles, CA
*Purpose: Literature on anonymous or ‘altruistic’ nondirected living liver donors (ND-LLDs) remains sparse as living donor liver transplant (LDLT) programs continue to explore the utilization…
2020 American Transplant Congress
Liver Plasmacytoid Dendritic Cells Express High Levels of DAP12, TREM2 and PD-L1 and Promote Effector T Cell Exhaustion and Augmented Treg Responses in Spontaneous Liver Transplant Tolerance
R. Nakano, O. Yoshida, S. Kimura, D. Geller, A. Thomson
University of Pittsburgh, Pittsburgh, PA
*Purpose: The precise mechanisms of liver transplant tolerance are yet to be elucidated. Non-conventional plasmacytoid dendritic cells (pDCs) are thought to promote immune regulation, including…
2020 American Transplant Congress
Inactive Status Changes Disproportionately Impacts the Probability of Obtaining a Deceased Donor Liver Transplant in Donation Service Areas with Higher MMaT
D. Haakinson¹, S. Noreen², D. Stewart², R. Batra¹, G. Gan¹, Y. Deng¹, S. Kulkarni¹
¹Yale, New Haven, CT, ²UNOS, Richmond, VA
*Purpose: Liver transplant (LT) rate is typically calculated by including both active and inactive patients, despite the fact that inactive patients are unable to receive…
2020 American Transplant Congress
Single-Cell RNA Sequencing Reveals Gene Expression Profiling of Ischemia Reperfusion Injury
L. Wang, S. He, J. Xu, Z. Guo, X. He
Organ Transplant Center, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China
*Purpose: Ischemia-reperfusion injury (IRI) during liver transplantation is an important factor that leads to graft dysfunction and even recipient death. This study aims to explore…
2020 American Transplant Congress
Concurrent Final Acceptance Associated with Decreased Deceased Donor Liver Utilization
A. Robinson¹, K. Shutterly², M. Sellers³, J. Rosendale¹, D. Brockmeier⁴
¹United Network for Organ Sharing, Richmond, VA, ²Center for Organ Recovery and Education, Pittsburgh, PA, ³Emory University Hospital and LifeLink of Georgia, Atlanta, GA, ⁴Mid-America Transplant Services, St. Louis, MO
*Purpose: With broader sharing for candidates with high MELD scores, it is not unusual for liver candidates to receive offers from multiple donors. Accepting multiple…
2020 American Transplant Congress
Impact of Donation after Circulatory Death Allografts on Outcomes Following Liver Re-Transplantation in the United States
S. Kumar¹, S. Lin², J. D. Schold²
¹Digestive Disease Institute, Cleveland Clinic Abu Dhabi, Abu Dhabi, United Arab Emirates, ²Quantitative Health Sciences, Cleveland Clinic Foundation, Cleveland, OH
*Purpose: Scarcity of donor organs in liver transplantation (LT) has necessitated consideration of donation after circulatory death (DCD) donors. Complications following LT and disease recurrence…
2020 American Transplant Congress
Acute Liver Failure Requiring Liver Transplantation Due to Acute Hepatitis A Infection: A Case Series
C. Xie¹, J. M. Fenkel¹, D. L. Halegoua-DeMarzio¹, J. M. Civan¹, D. M. Tholey¹, S. K. Herrine¹, M. Thapar¹, S. Arastu¹, A. M. Frank², A. P. Shah², J. M. Glorioso², C. G. Ramirez², A. S. Bodzin², W. R. Maley², D. A. Sass¹
¹Gastroenterology and Hepatology, Thomas Jefferson University, Philadelphia, PA, ²Transplant Surgery, Thomas Jefferson University, Philadelphia, PA
*Purpose: On August 1, Philadelphia declared a public health emergency regarding rapid increases in new acute hepatitis A virus (HAV) cases, with 355 locally-acquired cases…
2020 American Transplant Congress
Risk Prediction in the Meld-NA Era: The Tremendous Impact of Liver Related Complications
N. R. Mazumder¹, K. Atiemo², K. Jackson³, A. Daud⁴, A. Kho³, J. Levitsky¹, D. P. Ladner⁴
¹Gastroenterology and Hepatology, Northwestern University, Chicago, IL, ²Transplant Surgery, Tulane, New Orleans, LA, ³Center for Health Information Partnerships, Institute for Public Health and Medicine, Northwestern University, Chicago, IL, ⁴Transplant Surgery, Northwestern University, Chicago, IL
*Purpose: The MELD-Na score widely used for medical decision making but is not a good predictor of patient outcomes at low scores. Although portal hypertensive…
2020 American Transplant Congress
Taking on Pediatric Liver Tumors – Beyond Hepatoblastoma
U. Ekong, N. Yazigi, K. Khan, S. Kaufman, J. Guerra, R. Girlanda, J. Hawksworth, A. Kroemer, C. Matsumoto, T. Fishbein
MedStar Georgetown Transplant Institute, Washington, DC
*Purpose: Background. Hepatic angiosarcomas, hepatocellular carcinoma, hemangioendothelioma, and rhabdomyosarcoma of the bile ducts are very rare tumors in children with historically poor prognosis. Median survival…

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