Articles tagged "Liver transplantation"

2021 American Transplant Congress
Implementation of an Alcohol Screening Program Identifies Active Pre-transplant Drinking and Allows Engagement in Chemical Dependency Treatment
N. Lim¹, T. Leventhal¹, M. Thomson¹, M. Hassan¹, J. Thompson¹, S. Chinnakotla², V. Kirchner², T. Pruett², R. Kandaswamy², V. Humphreville², A. Adams², J. Lake¹
¹Division of Gastroenterology, Hepatology and Nutrition, University of Minnesota, Minneapolis, MN, ²Division of Transplantation, University of Minnesota, Minneapolis, MN
*Purpose: Alcohol (ETOH) is an important cause of cirrhosis in the US today. Screening patients for ETOH use prior to LT is important to identify…
2021 American Transplant Congress
Is Low Systemic Fibrinolytic Activity During the Anhepatic Phase Liver Transplant Surgery Associate with the Dreaded Post-Operative Complication of Hepatic Artery Thrombosis?
H. B. Moore¹, Y. Bababekov¹, J. Pomposelli¹, T. Ferrell¹, F. Azam¹, M. Adams², D. Yoeli¹, R. Choudhury¹, M. Wachs², E. Pomfret¹, T. Nydam¹
¹University of Colorado, Aurora, CO, ²Childrens Hospital Colorado, Aurora, CO
*Purpose: Removal of the native liver during transplantation results in impaired clearance of clot degrading proteins and activation of fibrinolysis as appreciated by Starzl in…
2021 American Transplant Congress
Liver Transplant Outcomes Using Nationally Allocated Grafts
S. Ohara¹, B. Lizaola-Mayo², P. Morgan², D. Das³, J. Wagler⁴, K. S. Reddy², B. Aqel², A. Moss², C. Jadlowiec²
¹Valleywise Health General Surgery Residency Program, Phoenix, AZ, ²Mayo Clinic, Phoenix, AZ, ³Mayo Clinic Alix School of Medicine, Scottsdale, AZ, ⁴John C Lincoln, Phoenix, AZ
*Purpose: There is national variation in acceptance criteria and utilization of livers across transplant centers. Data pertaining to outcomes of liver grafts declined by local…
2021 American Transplant Congress
Artificial Neural Network Application for MELDNa Prediction
L. Pruinelli¹, M. Nguyen¹, S. Olson¹, J. Zhou¹, J. Schold², T. Pruett¹, S. Ma¹, G. Simon¹
¹University of Minnesota, Minneapolis, MN, ²Cleveland Clinic Foundation, Cleveland, OH
*Purpose: The adoption of MELDNa decreased 90-days mortality on patients waiting for liver transplant (LT); however, there are no tools available to predict MELDNa trajectories…
2020 American Transplant Congress
Liver Transplant Waitlist Mortality is Not Associated with Urbanicity
Y. Chen¹, Y. Hung², Y. Hsu³, C. de Crescenzo¹, C. Rickert¹, J. Adler⁴, D. Chang¹, H. Yeh¹
¹Surgery, Massachusetts General Hospital, Boston, MA, ²Surgery, Sinai Hospital of Baltimore, Baltimore, MA, ³Harvard School of Public Health, Boston, MA, ⁴Surgery, Brigham and Women's Hospital, Boston, MA
*Purpose: Because of geographic disparity in transplant rates and organ usage, distance-based liver distribution has been proposed to replace Donor Service Area based distribution. However,…
2020 American Transplant Congress
Waitlist Mortality and Transplant Probability for Inactively Listed Liver Patients Depends on Donor Service Areas’ Median MELD at Transplant
R. Batra¹, S. Noreen², D. Stewart², D. Haakinson¹, G. Gan³, Y. Deng³, S. Kulkarni¹
¹Surgery, Yale University School of Medicine, New Haven, CT, ²UNOS, Richmond, VA, ³Yale University, New Haven, CT
*Purpose: Presently, the outcome of patients listed inactive on liver transplant waiting list (WL) are unknown; as inactive patients cannot receive deceased donor organ offers,…
2020 American Transplant Congress
Early Recurrence Of Hepatocellular Carcinoma Following Transplantation: Risk Score From A Multi-institutional Study Of > 3000 Patients
P. Tabrizian¹, M. Holzner², V. Agopian³, R. Busuttil³, G. Sapisochin⁴, N. Mehta⁵, F. Yao⁵, J. Roberts⁶, S. Florman¹, M. E. Schwartz¹, T. Ivanics⁷, J. Emond⁸, B. Samstein⁹, R. Brown, MD, MPH⁹, M. Najjar¹⁰, W. Chapman¹¹, M. Doyle¹¹, K. Halazun⁹
¹Transplant, Mount Sinai Medical Center, New York, NY, ²Surgery, Georgetown University Hospital, Washington DC, MD, ³Transplant, David Geffen School of Medicine at UCLA, Los Angeles, CA, ⁴Transplant, Univeristy of Toronto, Toronto, ON, Canada, ⁵Transplant, UCSF, San Francisco, CA, ⁶Transplantation, UCSF, San Francisco, CA, ⁷Transplant, University of Toronto, Toronto, ON, Canada, ⁸Transplant, Columbia University Medical Center, New York, NY, ⁹Transplant, Weill Cornell Medical Center, New York, NY, ¹⁰Transplant, Columbia Medical Center, New York, NY, ¹¹Transplant, Washington University School of Medicine, St Louis, MO
*Purpose: Early recurrence of hepatocellular carcinoma (HCC) after liver transplantation (LT) carries a poor prognosis. We aimed to develop a risk score for early HCC…
2020 American Transplant Congress
Higher Probability of Living Donor Liver Transplantation is Associated with DSAs Having a Higher Median Meld at Transplant
D. Haakinson¹, S. Noreen², D. Stewart², R. Batra¹, G. Gan¹, Y. Deng¹, S. Kulkarni¹
¹Yale, New Haven, CT, ²UNOS, Richmond, VA
*Purpose: Recent studies show that outcomes of living donor liver transplantation (LDLT) are superior compared to those receiving deceased donor grafts. Access to deceased donor…
2020 American Transplant Congress
Human Antigen R (HuR): A New Regulator of Heme Oxygenase-1 Cytoprotection in Mouse and Human Liver Transplantation
K. J. Dery¹, K. Nakamura², K. Kadono¹, H. Hirao¹, S. Kageyama¹, T. Ito¹, H. Kojima¹, F. Kaldas¹, R. W. Busuttil¹, J. W. Kupiec-Weglinski¹
¹Department of Surgery, Division of Liver and Pancreas Transplantation, UCLA, Los Angeles, CA, ²Surgery, Nishi-Kobe Medical Center, Hyogo, Japan
*Purpose: Ischemia-reperfusion injury (IRI) represents a risk factor in liver transplantation (LT). We have shown that overexpression of heme oxygenase 1 (HO-1) mitigates hepatic IRI…
2020 American Transplant Congress
Management of Hepatic Artery Stenosis Post Liver Transplant
S. Bommena, I. Joshi, P. Kang, T. Chaly, A. Seetharam, N. Patel, M. B. Fallon, S. Mehta
Banner University Medical Center, University of Arizona College of Medicine, Phoenix, AZ
*Purpose: Hepatic Artery Stenosis (HAS) is a significant complication after liver transplantation associated with morbidity. The primary aim of this study is to determine if…