ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Histology"

  • 2016 American Transplant Congress

    Treatment of Post-Transplant Focal Glomerulosclerosis: The Effect on Histopathology Lesions and Podocyte Foot Process Effacement.

    K. Koutroutsos,1 J. Moss,2 L. Moran,2 T. Cook,2 R. Charif,1 D. Taube,1 C. Roufosse,2 M. Loucaidou.1

    1Renal and Transplant Centre, Imperial Healthcare NHS Trust, London, United Kingdom; 2Department of Histopathology, Imperial Healthcare NHS Trust, London, United Kingdom.

    Background: Post-transplant Focal Segmental Glomerulosclerosis (FSGS) is associated with increased risk for renal allograft failure. It has been reported in the literature that podocyte foot…
  • 2016 American Transplant Congress

    Criteria for the Diagnosis of Microvascular Inflammation (MVI) in Kidney Transplant Biopsies (KTxBx).

    J. Grande,1 R. Leduc,2 The DeKAF Study Group.

    1Dept. of Lab Medicine & Pathology, Mayo Clinic College of Medicine, Rochester, MN; 2Division of Biostatistics, U. Minnesota School of Public Health, Minneapolis, MN.

    The presence of MVI (Banff glomerulitis "g" score and Banff peritubular capillary "ptc" score) in KTxBx, often related to antibody mediated rejection (AMR), is associated…
  • 2016 American Transplant Congress

    Clinical, Histologic and Charge Endpoints When Populations with Hepatitis C Recurrence Are Treated with Direct-Acting Antiviral or Interferon Based Therapies.

    S. Olson, A. McCann, S. Kumer, T. Schmitt, B. Floyd, R. Taylor, R. Gilroy.

    University of Kansas, Kansas City, KS.

    Background: While the primary endpoint for patients transplanted for Hepatitis C (HCV) has been established as sustained virologic response (SVR), different pathways have existed to…
  • 2016 American Transplant Congress

    Complexity of Hylinosis in Renal Transplant Biopsies: Donor Age, Glomerular Disease, and Time.

    G. Einecke,1 J. Reeve,2 P. Halloran.2,3

    1Nephrology, Hannover Medical School, Hannover, Germany; 2Alberta Transplant Applied Genomics Centre, Edmonton, Canada; 3Department of Medicine, Division of Nephrology and Transplant Immunology, University of Alberta, Edmonton, Canada.

    Arteriolar hyalinosis lesions (ah) are often interpreted as a sign of calcineurin inhibitor toxicity even though they are induced by other conditions. We studied the…
  • 2016 American Transplant Congress

    The Treatment of Borderline Lesion in Protocol Biopsies Did Not Improve the Outcome in Kidney Transplant Recipients.

    A. Flores-Mendoza, L. Marino-Vazquez, A. Guichard-Romero, N. Uribe-Uribe, R. Rivera-Marfil, A. Nuñez-Abreu, J. Alberu, L. Morales-Buenrostro.

    Nephrology, Transplantation and Pathology, National Institute of Medical Sciences and Nutrition SZ, Mexico, Distrito Federal, Mexico.

    Introduction. Up to 30% of patients with protocol biopsies and stable renal function have borderline lesions. His relationship with acute rejection remains uncertain, as does…
  • 2016 American Transplant Congress

    Lower Renal Graft Function and Accelerated Fibrosis in HIV-Infected Transplant Recipients with Previous HIVAN Compared to Non HIVAN HIV-Positive Transplant Recipients.

    M.-N. Peraldi,1 H. Ayari,1 M. Burbach,1 C. Randoux,2 E. Pillebout,1 N. De Castro,3 J.-M. Molina,3 D. Glotz.1

    1Nephrologie et Transplantation, Hôpital Saint-Louis et Université Paris-Diderot, Paris, France; 2Néphrologie, Hôpital Bichat et Université Paris-Diderot, Paris, France; 3Service de Maladies Infectieuses, Hôpital Saint-Louis et Université Paris-Diderot, Paris, France.

    Several studies reported reduced renal allograft survival rates among HIV-infected transplant recipients. Few data focus on histological lesions and their progression in renal grafts from…
  • 2016 American Transplant Congress

    Everolimus with Low-Dose Tacrolimus vs. a Standard Immunosuppressive Regimen: Renal Histology at 6 Months in De Novo Renal Transplant Patients.

    S. Yilmaz,1 D. Shaffer,2 F. Shihab,3 K. McCague,4 D. Patel,4 Y. Qazi,5 F. Vincenti.6

    1University of Calgary, Calgary, AB, Canada; 2Vanderbilt University, Nashville, TN; 3University of Utah, Salt Lake City, UT; 4Novartis Pharmaceuticals Corporation, East Hanover, NJ; 5University of Southern California, Los Angeles, CA; 6University of California San Francisco, San Francisco, CA.

    Morphologic changes in transplant protocol biopsies provide early evidence of renal damage. This study examined the renal histology of de novo patients 6 months post…
  • 2016 American Transplant Congress

    Randomized Controlled Study Evaluating Adherence Monitoring with Electronic Feedback on Reducing Renal Allograft Rejection.

    A. Bodzin, Y. Becker, M. Josephson, P. Witkowski, M. Lockwood, L. Potter, B. Kane, L. Lourenco, J. Millis.

    Transplant Center, University of Chicago, Chicago, IL.

    Purpose: The negative impact of non-adherence to the immunosuppressant medication (IM) regimen on transplant outcomes is well recognized. In an attempt to improve outcomes, the…
  • 2016 American Transplant Congress

    Association of Ultrastructural Changes in Renal Allograft Biopsies with Antibody-Mediated Rejection (AMR) and Graft Outcomes.

    A. Haririan,1 M. Chaudhry,2 J. Papadimitriou,2 N. Costa,1 B. Thomas,1 M. Mavanur,1 R. Ugarte,1 C. Cangro,1 C. Drachenberg.2

    1Dept of Medicine, Unniversity of Maryland, Baltimore, MD; 2Dept of Pathology, University of Maryland, Baltimore, MD.

    The role of electron microscopy (EM) in diagnosis of AMR is not well-defined. We sought to examine the EM findings in 796 biopsies from 622…
  • 2016 American Transplant Congress

    Kidney Structural Characteristics as Predictors of Long-Term Kidney Function in Living Kidney Donors.

    J. Mathew,1 A. Denic,1 M. Alexander,2 T. Vrtiska,3 H. Chakkera,4 S. Taler,1 A. Rule.1

    1Nephrology, Mayo Clinic, Rochester, MN; 2Pathology, Mayo Clinic, Rochester, MN; 3Radiology, Mayo Clinic, Rochester, MN; 4Nephrology, Mayo Clinic, Scottsdale, AZ.

    PurposeKidney structural characteristics may be predictive of long-term living donor outcomes such as a lower estimated Glomerular Filtration Rate (eGFR).MethodsAs part of the Renal and…
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