ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Histology"

  • 2020 American Transplant Congress

    Accelerated Decline in Glomerular Density: An Unrecognized Pathologic Process after Kidney Transplantation

    A. Denic, B. H. Smith, W. D. Park, M. V. Luhman, M. P. Alexander, A. D. Rule, M. D. Stegall

    Mayo Clinic, Rochester, Rochester, MN

    *Purpose: Studies in healthy adults have shown that glomerular density slowly declines with older age (-0.5% per decade), and globally sclerotic glomeruli (GSG) slowly increase…
  • 2020 American Transplant Congress

    Kidney Cortical Wedge Biopsies for Human Organ Research: Does Anatomic Variability Impact Their Utility?

    C. M. Edwards1, J. T. Langford1, M. Reschke2, J. R. DiRito1, D. Mulligan1, D. Haakinson1, G. T. Tietjen1

    1Surgery, Yale School of Medicine, New Haven, CT, 2Biomedical Engineering, Yale University, New Haven, CT

    *Purpose: The purpose of this study is to characterize human kidney anatomic variability both within singular biopsies and between biopsy sites in order to investigate…
  • 2020 American Transplant Congress

    Computer-Assisted Cardiac Histologic Evaluation (CACHE) for Grading Cardiac Allograft Rejection

    E. Peyster1, S. ArabYarmohommadi2, A. Janowczyk2, M. Sekulic3, C. Cassol4, M. Feldman1, K. Margulies1, A. Madabhushi2

    1University of Pennsylvania, Philadelphia, PA, 2Case Western Reserve University, Cleveland, OH, 3University Hospitals Cleveland Medical Center, Cleveland, OH, 4Ohio State University, Columbus, OH

    *Purpose: Cardiac allograft rejection (CAR) is a serious concern in heart transplantation, occurring in 30-40% of patients during the first year. Endomyocardial biopsy (EMB) with…
  • 2020 American Transplant Congress

    Effects of Mandatory 6-Month Waiting Time Policy on Post-Transplant Outcomes and Explant Pathology in Liver Transplant Patients with Hepatocellular Carcinoma

    S. Nagai, T. Kitajima, S. Yeddula, R. Salgia, M. Abouljoud, D. Moonka

    Henry Ford Hospital, Detroit, MI

    *Purpose: In the United States, current allocation policy mandates a 6-month waiting period before exception scores are granted to liver transplant (LT) candidates with hepatocellular…
  • 2020 American Transplant Congress

    Recurrent Lupus Post Kidney Transplantation- The Histological and Clinical Characteristics

    A. Bentall1, W. Jiqiu2, A. Kattah1, M. L. Gonzalez Suarez3, F. G. Cosio1, M. Mai4, H. Khamash5, M. D. Stegall6, H. Amer1, L. D. Cornell7, F. Fervenza1, M. P. Alexander7

    1Division of Nephrology and Hypertension, Mayo Clinic, Rochester, MN, 2National Clinical Research Center of Kidney Diseases, Nanjing University, Nanjing, China, 3Department of Nephrology, University of Mississippi Medical Center, Jackson, MS, 4Division of Nephrology and Hypertension, Mayo Clinic, Jackonville, FL, 5Division of Nephrology and Hypertension, Mayo Clinic, Scottdale, AZ, 6Department of Transplant Surgery, Mayo Clinic, Rochester, MN, 7Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN

    *Purpose: Lupus nephritis (LN) progresses to ESRD in
  • 2020 American Transplant Congress

    Recurrent Diabetic Nephropathy Post Kidney Transplant is Associated with High Risk of Mortality

    A. Kukla, M. Merzkani, W. Park, B. Smith, S. Turkevi-Nagy, P. Zhang, X. Benavides, M. Morales Alvarez, A. Denic, A. Bentall, Y. Kudva, M. D'Costa, P. Alexander, M. Stegall

    Mayo Clinic, Rochester, MN

    *Purpose: The goal of the study was to determine the incidence of recurrent diabetic kidney disease (DKD) after kidney transplantation (KT) and assess its correlation…
  • 2020 American Transplant Congress

    Significance of Pathology in Antibody Mediated Rejection in Pediatric Kidney Transplant Recipients on 1 Year Outcomes: Interim Results of the Paramour “Pediatric Renal AMR Outcomes” Study

    I. Ashoor1, A. Jain2, R. Garro3, M. Kallash4, S. Soloman5, K. Twombley6

    1LSUHSC and Children's Hospital New Orleans, New Orleans, LA, 2Children's Hospital of Michigan, Detroit, MI, 3Emory University School of Medicine and Children’s Healthcare of Atlanta, Atlanta, GA, 4Nationwide Children's Hospital, Columbus, OH, 5Maria Fareri Children's Hospital at Westchester Medical Center, Valhalla, NY, 6Medical University of South Carolina, Charleston, SC

    *Purpose: Little is known about how pathology findings on biopsy correlate with outcomes in pediatric kidney transplant patients with antibody mediated rejection (AMR). We aimed…
  • 2019 American Transplant Congress

    Immunomics of Renal Allograft Acute T-Cell Mediated Rejection Biopsies of Tacrolimus- and Belatacept- Treated Patients

    M. van der Zwan1, C. C. Baan1, R. C. Colvin2, R. N. Smith2, R. A. White2, D. N. Ndishabandi2, A. L. Nigg1, T. P. van den Bosch1, G. N. de Graav1, M. C. Clahsen-van Groningen1, D. A. Hesselink1

    1Internal Medicine, Division Nephrology and Transplantation, Erasmus MC, Rotterdam, Netherlands, 2Pathology, Massachusetts General Hospital/Harvard Medical School, Boston, MA

    *Purpose: Belatacept-based therapy in kidney transplant recipient has been shown to increase long-term renal allograft and patient survival compared with calcineurin inhibitor based therapy, however…
  • 2019 American Transplant Congress

    Clinical Response to Pathological Finding in Uterus Transplantation

    L. Johannesson, G. Testa

    Simmons Transplant Institute, Baylor University Medical Center, Dallas, TX

    *Purpose: Uterus transplantation has recently proven to be the first successful treatment for absolute uterine factor infertility with demonstration of live births. All reported episodes…
  • 2019 American Transplant Congress

    First UK Experience of the Molecular Microscope (MMDX™) in the Kidney Transplant Clinic

    C. Lawrence1, S. Thiru2, A. Manoj1, S. Fluck1

    1Renal Medicine, The Lister Hospital, Stevenage, United Kingdom, 2Histopathology, Addenbrookes Hospital, Cambridge, United Kingdom

    *Purpose: Molecular diagnostic methods are now included in the Banff classification of kidney transplant pathology. Traditional histopathology may be limited by intra/inter pathologist variation. The…
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