2022 American Transplant Congress
Circulating and Intragraft Donor (HLA)-Specific B Cells Drive Allograft Rejection After Kidney Transplantation
*Purpose: Besides donor-specific antibodies (DSA), circulating donor(HLA)-specific memory B cells (mBc) have also shown to play a deleterious role driving antibody-mediated rejection (ABMR) in kidney…2022 American Transplant Congress
Histopathology at Diagnosis and One-Year Outcomes in Antibody Mediated Rejection in Pediatric Kidney Transplant Recipients: Preliminary Findings from the Paramour “Pediatric Renal AMR Outcomes” Study
*Purpose: Antibody mediated rejection (AMR) is a major cause of kidney allograft dysfunction leading to graft loss. There is a paucity of data regarding how…2022 American Transplant Congress
Pre-Transplant Evaluation of Patients Undergoing Combined Heart-Liver Transplantation and Correlation with Explant Pathology
*Purpose: Fontan-associated liver disease (FALD) is a well-described complication of Fontan physiology. More patients with failing Fontan are being evaluated for heart transplant and evidence-based…2022 American Transplant Congress
Single Cell Multiomics Reveals Immune Mediators in Acute Cellular Rejection Following Pediatric Liver Transplantation
*Purpose: Acute cellular rejection (ACR) is a common complication following pediatric liver transplantation with potential negative effects on allograft longevity. Currently, diagnosis and management are…2022 American Transplant Congress
Recoverability of Diabetic Nephropathy of Donor Kidney After Kidney Transplantation
Samsung Medical Center, Seoul, Korea, Republic of
*Purpose: The natural course of diabetic donors on the outcome of kidney transplantation (KT) is controversial. The aim of this study was to analyze the…2021 American Transplant Congress
Impact of Treatment of Subclinical Rejection at 2 Weeks After Kidney Transplantation, Compared by 1 Year Histologic Outcomes
*Purpose: Subclinical rejection (SCR) is associated with chronic allograft nephropathy, which is the most common cause of allograft failure in kidney transplantation (KT). Therefore, early…2021 American Transplant Congress
Plasma Donor-Derived Cell-Free DNA Levels Risk-Stratify Kidney Allograft Injury with Isolated Transplant Glomerulitis
*Purpose: The Banff lesion Glomerulitis (g) characterizes the degree of microvascular glomerular inflammation. Some studies have demonstrated glomerulitis in the absence of C4d in association…2021 American Transplant Congress
Treatment of Refractory Chronic Active Antibody-Mediated Rejection: Improvement in Histopathology are Delayed Compared to the Reduction in Donor Specific Antibodies
1University of Wisconsin, Madison, WI, 2University of Manitoba, Winnipeg, MB, Canada
*Purpose: There are limited options for the treatment and management of refractory chronic active antibody-mediated rejection (cABMR) after kidney transplantation. Longitudinal histologic data in patients…2021 American Transplant Congress
Association of Donor-Derived Cell-Free DNA with Severity of Interstitial Fibrosis and Cortical Atrophy Lesions Following Kidney Transplantation
*Purpose: The most common cause of kidney transplant (KT) failure is the poorly characterized histopathologic entity “interstitial fibrosis and tubular atrophy” (IFTA). There are no…2021 American Transplant Congress
Perivenular Fibrosis After Pediatric Liver Transplant
*Purpose: Graft fibrosis is a concerning long-term complication after pediatric liver transplant (LT) and though perivenular (PV) fibrosis is common, its likelihood of progression and…
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