Articles tagged "Histology"

2020 American Transplant Congress
Recurrent Lupus Post Kidney Transplantation- The Histological and Clinical Characteristics
A. Bentall¹, W. Jiqiu², A. Kattah¹, M. L. Gonzalez Suarez³, F. G. Cosio¹, M. Mai⁴, H. Khamash⁵, M. D. Stegall⁶, H. Amer¹, L. D. Cornell⁷, F. Fervenza¹, M. P. Alexander⁷
¹Division of Nephrology and Hypertension, Mayo Clinic, Rochester, MN, ²National Clinical Research Center of Kidney Diseases, Nanjing University, Nanjing, China, ³Department of Nephrology, University of Mississippi Medical Center, Jackson, MS, ⁴Division of Nephrology and Hypertension, Mayo Clinic, Jackonville, FL, ⁵Division of Nephrology and Hypertension, Mayo Clinic, Scottdale, AZ, ⁶Department of Transplant Surgery, Mayo Clinic, Rochester, MN, ⁷Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN
*Purpose: Lupus nephritis (LN) progresses to ESRD in
2020 American Transplant Congress
Recurrent Diabetic Nephropathy Post Kidney Transplant is Associated with High Risk of Mortality
A. Kukla, M. Merzkani, W. Park, B. Smith, S. Turkevi-Nagy, P. Zhang, X. Benavides, M. Morales Alvarez, A. Denic, A. Bentall, Y. Kudva, M. D'Costa, P. Alexander, M. Stegall
Mayo Clinic, Rochester, MN
*Purpose: The goal of the study was to determine the incidence of recurrent diabetic kidney disease (DKD) after kidney transplantation (KT) and assess its correlation…
2020 American Transplant Congress
Significance of Pathology in Antibody Mediated Rejection in Pediatric Kidney Transplant Recipients on 1 Year Outcomes: Interim Results of the Paramour “Pediatric Renal AMR Outcomes” Study
I. Ashoor¹, A. Jain², R. Garro³, M. Kallash⁴, S. Soloman⁵, K. Twombley⁶
¹LSUHSC and Children's Hospital New Orleans, New Orleans, LA, ²Children's Hospital of Michigan, Detroit, MI, ³Emory University School of Medicine and Children’s Healthcare of Atlanta, Atlanta, GA, ⁴Nationwide Children's Hospital, Columbus, OH, ⁵Maria Fareri Children's Hospital at Westchester Medical Center, Valhalla, NY, ⁶Medical University of South Carolina, Charleston, SC
*Purpose: Little is known about how pathology findings on biopsy correlate with outcomes in pediatric kidney transplant patients with antibody mediated rejection (AMR). We aimed…
2019 American Transplant Congress
Immunomics of Renal Allograft Acute T-Cell Mediated Rejection Biopsies of Tacrolimus- and Belatacept- Treated Patients
M. van der Zwan¹, C. C. Baan¹, R. C. Colvin², R. N. Smith², R. A. White², D. N. Ndishabandi², A. L. Nigg¹, T. P. van den Bosch¹, G. N. de Graav¹, M. C. Clahsen-van Groningen¹, D. A. Hesselink¹
¹Internal Medicine, Division Nephrology and Transplantation, Erasmus MC, Rotterdam, Netherlands, ²Pathology, Massachusetts General Hospital/Harvard Medical School, Boston, MA
*Purpose: Belatacept-based therapy in kidney transplant recipient has been shown to increase long-term renal allograft and patient survival compared with calcineurin inhibitor based therapy, however…
2019 American Transplant Congress
Clinical Response to Pathological Finding in Uterus Transplantation
L. Johannesson, G. Testa
Simmons Transplant Institute, Baylor University Medical Center, Dallas, TX
*Purpose: Uterus transplantation has recently proven to be the first successful treatment for absolute uterine factor infertility with demonstration of live births. All reported episodes…
2019 American Transplant Congress
First UK Experience of the Molecular Microscope (MMDX™) in the Kidney Transplant Clinic
C. Lawrence¹, S. Thiru², A. Manoj¹, S. Fluck¹
¹Renal Medicine, The Lister Hospital, Stevenage, United Kingdom, ²Histopathology, Addenbrookes Hospital, Cambridge, United Kingdom
*Purpose: Molecular diagnostic methods are now included in the Banff classification of kidney transplant pathology. Traditional histopathology may be limited by intra/inter pathologist variation. The…
2019 American Transplant Congress
Role of Kidney Biopsy in Simultaneous Heart-Kidney Transplantation
P. B. Shah¹, M. A. Josephson¹, K. Henriksen², A. Chang²
¹Nephrology, University of Chicago Medicine, Chicago, IL, ²Pathology, University of Chicago Medicine, Chicago, IL
*Purpose: Simultaneous heart-kidney (SHK) transplantation has superior post-transplant survival compared to heart transplantation alone in end-stage heart failure patients who have dialysis dependent or non-dialysis…
2019 American Transplant Congress
Reduction of Circulating DSA: Does It Affect Histology?
M. Gupta¹, E. Edusei¹, S. Tsai², M. Magruder², J. Lee¹, J. Lee¹, C. Hartono¹, T. Muthukumar¹, M. Everly³, D. Dadhania¹
¹Nephrology, New York Presbyterian Weill Cornell, New York, NY, ²New York Presbyterian Weill Cornell, New York, NY, ³Terasaki Research Institute, Los Angeles, CA
*Purpose: De novo donor specific antibodies (dnDSA) are reported in 13-30% of kidney transplant recipients. dnDSA has been associated with antibody mediated rejection (AMR) and…
2019 American Transplant Congress
Kidney Biopsies In Hiv-negative To Hiv-positive Kidney Transplants – An Institutional Experience
V. Walavalkar¹, A. Zarinsefat², A. Urisman¹, D. Dobi¹, J. Vasquez³, P. Stock², Z. Laszik¹
¹Pathology, UCSF Medical Center, San Francisco, CA, ²Transplant Surgery, UCSF Medical Center, San Francisco, CA, ³Medicine, UCSF Medical Center, San Francisco, CA
*Purpose: Increased life expectancy in HIV+ patients has resulted in an increase in CKD leading to ESRD; and therefore renal transplantation in these individuals is…
2019 American Transplant Congress
Living Kidney Donor Time Zero Biopsy Findings Predict Graft Loss in the Recipient
N. Issa¹, C. Lopez¹, A. Denic¹, J. J. Larson¹, R. Narasimhan¹, L. Archila¹, S. S. Taler¹, H. Chakkera², J. Augustine³, M. Stegall⁴, A. Rule¹
¹Nephrology, Mayo Clinic, Rochester, MN, ²Nephrology, Mayo Clinic, Phoenix, AZ, ³Nephrology, Cleveland Clinic, Cleveland, OH, ⁴Transplantation, Mayo Clinic, Rochester, MN
*Purpose: Recipient outcomes with living donor kidney grafts are superior to those achieved from deceased donors. However, there may still be variability in the quality…