ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Histology"

  • 2021 American Transplant Congress

    Plasma Donor-Derived Cell-Free DNA Levels Risk-Stratify Kidney Allograft Injury with Isolated Transplant Glomerulitis

    L. Bu1, S. Anand2, A. Pai3, J. S. Bromberg4, G. Gupta5, I. Moinuddin5, T. Alhamad6, V. Bowers7, S. Ghosh8, W. Tian8, E. Stites9

    1University of Minnesota, Minneapolis, MN, 2Intermountain Medical Center, Murray, UT, 3University of Texas McGovern Medical School, Houston, TX, 4University of Maryland School of Medicine, Baltimore, MD, 5Virginia Commonwealth University, Richmond, VA, 6Washington University in St. Louis, St. Louis, MO, 7Tampa General Hospital, Tampa, FL, 8CareDx, Brisbane, CA, 9University of Colorado, Aurora, CO

    *Purpose: The Banff lesion Glomerulitis (g) characterizes the degree of microvascular glomerular inflammation. Some studies have demonstrated glomerulitis in the absence of C4d in association…
  • 2021 American Transplant Congress

    Treatment of Refractory Chronic Active Antibody-Mediated Rejection: Improvement in Histopathology are Delayed Compared to the Reduction in Donor Specific Antibodies

    K. R. Degner1, S. Parajuli1, F. Aziz1, N. Garg1, M. Mohamed1, D. A. Mandelbrot1, S. E. Panzer1, L. Hidalgo1, N. A. Wilson1, S. R. Reese1, K. Van Hyfte1, W. Zhong1, P. Nickerson2, A. Djamali1

    1University of Wisconsin, Madison, WI, 2University of Manitoba, Winnipeg, MB, Canada

    *Purpose: There are limited options for the treatment and management of refractory chronic active antibody-mediated rejection (cABMR) after kidney transplantation. Longitudinal histologic data in patients…
  • 2021 American Transplant Congress

    Association of Donor-Derived Cell-Free DNA with Severity of Interstitial Fibrosis and Cortical Atrophy Lesions Following Kidney Transplantation

    L. Bu1, E. Stites2, V. Bowers3, T. Alhamad4, J. S. Bromberg5, G. Gupta6, I. Moinuddin6, S. Ghosh7, W. Tian7, A. Pai8, S. Anand9

    1University of Minnesota, Minneapolis, MN, 2University of Colorado, Aurora, CO, 3Tampa General Hospital, Tampa, FL, 4Washington University in St. Louis, St. Louis, MO, 5University of Maryland School of Medicine, Baltimore, MD, 6Virginia Commonwealth University, Richmond, VA, 7CareDx, Brisbane, CA, 8University of Texas McGovern Medical School, Houston, TX, 9Intermountain Medical Center, Murray, UT

    *Purpose: The most common cause of kidney transplant (KT) failure is the poorly characterized histopathologic entity “interstitial fibrosis and tubular atrophy” (IFTA). There are no…
  • 2021 American Transplant Congress

    Perivenular Fibrosis After Pediatric Liver Transplant

    J. Lew, S. Cho, S. Feng, E. R. Perito

    UCSF, San Francisco, CA

    *Purpose: Graft fibrosis is a concerning long-term complication after pediatric liver transplant (LT) and though perivenular (PV) fibrosis is common, its likelihood of progression and…
  • 2020 American Transplant Congress

    Computer-Assisted Cardiac Histologic Evaluation (CACHE) for Grading Cardiac Allograft Rejection

    E. Peyster1, S. ArabYarmohommadi2, A. Janowczyk2, M. Sekulic3, C. Cassol4, M. Feldman1, K. Margulies1, A. Madabhushi2

    1University of Pennsylvania, Philadelphia, PA, 2Case Western Reserve University, Cleveland, OH, 3University Hospitals Cleveland Medical Center, Cleveland, OH, 4Ohio State University, Columbus, OH

    *Purpose: Cardiac allograft rejection (CAR) is a serious concern in heart transplantation, occurring in 30-40% of patients during the first year. Endomyocardial biopsy (EMB) with…
  • 2020 American Transplant Congress

    Effects of Mandatory 6-Month Waiting Time Policy on Post-Transplant Outcomes and Explant Pathology in Liver Transplant Patients with Hepatocellular Carcinoma

    S. Nagai, T. Kitajima, S. Yeddula, R. Salgia, M. Abouljoud, D. Moonka

    Henry Ford Hospital, Detroit, MI

    *Purpose: In the United States, current allocation policy mandates a 6-month waiting period before exception scores are granted to liver transplant (LT) candidates with hepatocellular…
  • 2020 American Transplant Congress

    Recurrent Lupus Post Kidney Transplantation- The Histological and Clinical Characteristics

    A. Bentall1, W. Jiqiu2, A. Kattah1, M. L. Gonzalez Suarez3, F. G. Cosio1, M. Mai4, H. Khamash5, M. D. Stegall6, H. Amer1, L. D. Cornell7, F. Fervenza1, M. P. Alexander7

    1Division of Nephrology and Hypertension, Mayo Clinic, Rochester, MN, 2National Clinical Research Center of Kidney Diseases, Nanjing University, Nanjing, China, 3Department of Nephrology, University of Mississippi Medical Center, Jackson, MS, 4Division of Nephrology and Hypertension, Mayo Clinic, Jackonville, FL, 5Division of Nephrology and Hypertension, Mayo Clinic, Scottdale, AZ, 6Department of Transplant Surgery, Mayo Clinic, Rochester, MN, 7Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN

    *Purpose: Lupus nephritis (LN) progresses to ESRD in
  • 2020 American Transplant Congress

    Recurrent Diabetic Nephropathy Post Kidney Transplant is Associated with High Risk of Mortality

    A. Kukla, M. Merzkani, W. Park, B. Smith, S. Turkevi-Nagy, P. Zhang, X. Benavides, M. Morales Alvarez, A. Denic, A. Bentall, Y. Kudva, M. D'Costa, P. Alexander, M. Stegall

    Mayo Clinic, Rochester, MN

    *Purpose: The goal of the study was to determine the incidence of recurrent diabetic kidney disease (DKD) after kidney transplantation (KT) and assess its correlation…
  • 2020 American Transplant Congress

    Significance of Pathology in Antibody Mediated Rejection in Pediatric Kidney Transplant Recipients on 1 Year Outcomes: Interim Results of the Paramour “Pediatric Renal AMR Outcomes” Study

    I. Ashoor1, A. Jain2, R. Garro3, M. Kallash4, S. Soloman5, K. Twombley6

    1LSUHSC and Children's Hospital New Orleans, New Orleans, LA, 2Children's Hospital of Michigan, Detroit, MI, 3Emory University School of Medicine and Children’s Healthcare of Atlanta, Atlanta, GA, 4Nationwide Children's Hospital, Columbus, OH, 5Maria Fareri Children's Hospital at Westchester Medical Center, Valhalla, NY, 6Medical University of South Carolina, Charleston, SC

    *Purpose: Little is known about how pathology findings on biopsy correlate with outcomes in pediatric kidney transplant patients with antibody mediated rejection (AMR). We aimed…
  • 2020 American Transplant Congress

    Efficacy of Radiofrequency Ablation in the Treatment of Patients with Hepatocellular Carcinoma and Compensated Liver Disease: A Pathological Evaluation of Liver Explants

    W. Alhamoudi1, I. Salih2, S. Yousif2, M. Shawkat3, K. Bzeizi2, A. Albenmousa2, S. Alghamdi2, M. Sturdevant2, D. Broering2, H. Alsuhaibani2

    1Medicine, King Saud University, Riyadh, Saudi Arabia, 2Liver Transplant, King Faisal Specialist Hospital, Riyadh, Saudi Arabia, 3Internal Medicine, Minia University, Minia, Egypt

    *Purpose: Radiofrequency ablation (RFA) is a safe and effective treatment for patients with limited hepatocellular carcinoma (HCC). Ablative outcomes have been largely based on radiological…
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