2015 American Transplant Congress
Treatment of Subclinical Rejection Identified On Surveillance Biopsy May Prevent the Development of Chronic Alloimmune Injury
Imperial College Kidney and Transplant Centre, Hammersmith Hospital, London, United Kingdom.
Surveillance biopsies [SBx] are not universally performed following renal transplantation. In patients in whom protocol biopsies are performed, how best to manage subclinical rejection [SCR]…2015 American Transplant Congress
Post-Transplant Recurrence of Calcium Oxalate Crystals in Primary Hyperoxaluria Type 1 Detected by Surveillance Biopsies: Incidence, Risk Factors, and Effect on Graft Function
Background: Primary hyperoxaluria type 1 (PH1) is a rare metabolic defect that results in oxalate over-production by the liver and leads to renal disease due…2015 American Transplant Congress
A New Diagnostic and Pronostic Tool for Antibody Mediated Rejection in Kidney Transplantation: Intragraft Donor Specific Anti-HLA Antibodies Detection
INTRODUCTION: Antibody mediated rejection (AMR) is one of the main cause of loss of the kidney transplant. Despite the new BANFF classification, diagnostic difficulties and…2015 American Transplant Congress
MYH9 Polymorphic Variants and Chronic Lesions in Transplanted Kidney Biopsy
MYH9 encoding a non-muscle myosin heavy chain IIA is expressed in podocytes, mesangial, tubular, capillary endothelial cells and vascular wall. Intronic variants of MYH9 associate…2015 American Transplant Congress
Banff Criteria Are Inadequate to Assess Chronic Renal Allograft Injury 10 Years Post-Transplantation
Background: The Banff criteria have been developed to assess acute and chronic injury in renal allografts. However, the criteria have been based on biopsies for…2015 American Transplant Congress
Morphometry of the Epithelial-Mesenchymal Transition (EMT) in Subsequent Biopsies from Transplanted Kidney
EMT plays the principal role in the pathogenesis of IF/TA as a consequence in the failure of a transplanted kidney. Many facts suggest that the…2015 American Transplant Congress
Outcome of Kidney Transplantation from Older Living Donors: Histological Evaluation Using Zero-Time Biopsy Specimens
OBJECTIVE: The relationship between preimplantation biopsy and graft outcome in kidney transplantations from older living donors has not been studied yet. We reviewed graft outcomes…2015 American Transplant Congress
Outcome of Kidney Transplantation from Obese Living Donors: Histological Evaluation Using Zero-Time Biopsy Specimens
BACKGROUND AND OBJECTIVE: The relationship between preimplantation biopsy and graft outcome in kidney transplantation from obese living donors has not been studied. We reviewed graft…2015 American Transplant Congress
Transplant Glomerulopathy in a Novel Model of Chronic Antibody Mediated Rejection Is Associated With DSA and Glomerular IgM
PurposeChronic active antibody mediated rejection (cAMR) and transplant glomerulopathy (TG) are major determinants of long-term allograft survival. However, the contribution of DSA and glomerular immunoglobulins…2015 American Transplant Congress
Distinct Subtypes of Rejection in a Novel Non Human Primate Model of Sensitization
[Background] Preformed and newly formed alloantibody post transplantation (TX) can significantly deteriorate graft survival. Patterns of humoral rejection in sensitized patients varies significantly due to…