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Articles tagged "Heart"

  • 2020 American Transplant Congress

    The Liver Protects All? Donor Specific Antibody Formation in Heart-Liver Transplant Recipients

    A. W. Rogers1, T. N. Eagar2, C. Pham1, J. Krisl1, B. J. Pierce1, M. Moaddab1, R. Ghobrial3, B. Trachtenberg4, A. Bhimaraj4, A. O. Gaber3

    1Department of Pharmacy, Houston Methodist Hospital, Houston, TX, 2Department of Pathology, Houston Methodist Hospital, Houston, TX, 3Department of Surgery, Houston Methodist Hospital, Houston, TX, 4Houston Methodist Hospital, Houston, TX

    *Purpose: Donor specific antibodies (DSAs) are key in the development of antibody mediated rejection (AMR). Their role in decreased patient and graft survival has been…
  • 2020 American Transplant Congress

    Neonatal Tolerance Induction: Behaviours of Allogeneic Spleen and Bone Marrow Inocula in Neonatal Mice are Largely Determined by the Nature of Their CD8 T Cells

    R. A. Bascom, K. Tao, L. J. West

    University of Alberta, Edmonton, AB, Canada

    *Purpose: Injected adult allo-spleen (SC) and bone marrow cells (BMC) traffic to secondary lymphoid organs, proliferate and spread throughout neonatal mice; allo-SC consistently cause acute…
  • 2020 American Transplant Congress

    Combined Heart-Liver Transplantation: A Systematic Review of the Literature

    I. A. Ziogas1, D. Giannis2, P. Kapsampelis2, A. Giannopoulou2, A. Evangeliou2, K. S. Mylonas2, G. Tsoulfas3, L. K. Matsuoka1, M. I. Montenovo1, M. Izzy1, S. P. Alexopoulos1

    1Vanderbilt University Medical Center, Nashville, TN, 2Society of Junior Doctors, Athens, Greece, 3Aristotle University of Thessaloniki, Thessaloniki, Greece

    *Purpose: Combined heart-liver transplant (CHLT) has been increasingly utilized as the treatment of choice for candidates with dual end-stage organ disease. We aimed to assess…
  • 2019 American Transplant Congress

    Geographic Disparities in Heart Transplant Rates

    M. Kosztowski, S. Yu, A. Kilic, A. Massie, S. Zhou, D. Segev, S. Gentry

    JHU, Baltimore, MD

    *Purpose: One of the motivations for the recent changes to the heart allocation policy was to reduce geographic disparities. We investigated whether heart transplant (HT)…
  • 2019 American Transplant Congress

    Analyzing The Effect Of Liver Transplantation On Myocardial Strain Using Speckle Tracking Echocardiography In Nonalcoholic Steatohepatitis (NASH) Patients

    A. Chhatriwala, M. Lam, E. Kim, S. Raissi, N. Mazumder, J. Thomas, H. Maddur, M. Rinella

    Northwestern Memorial Hospital, Chicago, IL

    *Purpose: Nonalcoholic Steatohepatitis (NASH) is currently the second most common indication for liver transplant in the United States and is projected to increase in the…
  • 2019 American Transplant Congress

    Risk Factors to Define an Extended Criteria Donor Heart Do Not Appear to Have Cumulative Adverse Effects after Heart Transplantation

    M. Olymbios, S. Dimbil, R. J. Levine, F. Esmailian, J. Patel, J. A. Kobashigawa

    Cedars-Sinai Smidt Heart Institute, Los Angeles, CA

    *Purpose: There remains a disparity between the number of patients awaiting heart transplantation (HTx) and the availability of donor hearts. This is exacerbated by relatively…
  • 2019 American Transplant Congress

    Cardiac Risk Assessment in Kidney Transplant Candidates: Clinical Usefulness of Different Guidelines

    A. Velioglu1, S. Mehdiyev1, H. Arikan1, E. Asicioglu1, A. Cincin2, S. Tuglular1

    1Nephrology, Marmara University School of Medicine, Istanbul, Turkey, 2Cardiology, Marmara University School of Medicine, Istanbul, Turkey

    *Purpose: Despite cardiovascular (CV) assessment recommended all kidney transplant recipients to minimize perioperative risk, the utility and reliability of various assessments are not well established.…
  • 2019 American Transplant Congress

    Local IL-33 Regulates Heart Transplant Infiltrating Myeloid Cells Metabolism and Differentiation to Protect against Chronic Rejection

    Z. Zhang1, Q. Liu1, T. Li1, G. S. Hussey2, M. Velayutham1, J. L. Dziki2, L. R. Mathews1, Y. C. Lee2, G. K. Dwyer1, H. Dai1, A. S. Roessing1, S. Shiva3, M. H. Oberbarnscheidt1, S. F. Badylak2, H. R. Turnquist1

    1Department of Surgery, Thomas E. Starzl Transplantation Institute, Pittsburgh, PA, 2Department of Bioengineering, McGowan Institute for Regenerative Medicine, Pittsburgh, PA, 3Department of Pharmacology and Chemical Biology, Vascular Medicine Institute, Pittsburgh, PA

    *Purpose: Self-molecules containing damage-associated molecular patterns stimulate the pro-inflammatory response of infiltrating innate immune cells after their release during tissue injury. Yet, if local endogenous…
  • 2019 American Transplant Congress

    ­Pediatric Heart and Lung Graft Loss during the “High-Risk Age Window”

    J. Long1, J. Motter1, K. R. Jackson1, M. Kosztowski1, B. Orandi2, X. Luo1, K. Van Arendonk3, A. Massie1, E. Bush1, R. S. Higgins1, D. L. Segev1, J. M. Garonzik-Wang1

    1Johns Hopkins School of Medicine, Baltimore, MD, 2University Of Alabama at Birmingham, Birmingham, AL, 3Children’s Hospital of Wisconsin-Milwaukee Campus, Milwaukee, WI

    *Purpose: Pediatric kidney transplant recipients experience a high-risk age window of increased graft loss during late adolescence and early adulthood (17-24 years), termed emerging adulthood.…
  • 2019 American Transplant Congress

    Can Cardiac Risk Predictor Models Be Trusted in Kidney Transplant Recipients?

    K. L. Hoffman1, R. R. Alloway1, A. Shields2, E. Woodle2, A. Govil1

    1Nephrology & Transplant Medicine, University of Cincinnati, Cincinnati, OH, 2Transplant Surgery, University of Cincinnati, Cincinnati, OH

    *Purpose: Kidney transplant recipients (KTR) bear a higher risk of developing cardiovascular disease due to comorbid conditions. Non-invasive cardiovascular risk stratification tools have not been…
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