2022 American Transplant Congress
Correlating Histology, Immunohistochemical, & Serologic Data in Heart Transplant Recipients: Implications for Molecular Diagnostic Assays
University of Pittsburgh Medical Center, Pittsburgh, PA
*Purpose: The ISHLT classification of rejection in heart allograft biopsies is independent of DSA status. There is only limited data on the prevalence of DSA…2022 American Transplant Congress
Significant Reduction of Troponin I Elaboration After Ischemia Minimization in the First Hour of Ex Vivo Xeno Heart Perfusion
*Purpose: Previous studies showed that ischemia minimization (IM), accomplished by perfusing the heart xenograft during storage, prevents ‘initial cardiac xenograft dysfunction’ (ICXD) and enables prolonged…2022 American Transplant Congress
Equity in Access to Deceased Donor Transplant for Candidates on the Heart Waitlist
*Purpose: Transplantation is often the gold standard therapy for those with organ failure, but limited supply prevents all patients from accessing this treatment. The Organ…2022 American Transplant Congress
Association Between Allograft Gene Expression and Acute Cellular Rejection Grade in Heart Transplant Recipients
*Purpose: Endomyocardial biopsy (EMB) remains the gold standard in acute rejection (AR) surveillance in heart transplantation (HT) despite interpretation subjectivity and low concordance rates between…2022 American Transplant Congress
The Use of Donor-Derived Cell-Free DNA in Female and Male Heart Transplant Recipients: A Sex-Specific Analysis of the Surveillance Heartcare Outcomes Registry
*Purpose: To investigate sex-specific donor-derived cell-free DNA AlloSure (AS) levels during allograft quiescence and rejection after heart transplantation.*Methods: Sex-stratified data were obtained from the Surveillance…2022 American Transplant Congress
Impaired Left Ventricular Global Longitudinal Strain: Clinical Presentation and Outcomes in Liver Transplantation Recipients without Arrhythmia or Structural Heart Disease
University of Maryland School of Medicine, Baltimore, MD
*Purpose: Assess the prevalence and characteristics of patients without arrhythmia or structural heart disease (SHD) but with impaired pre-transplant left ventricular global longitudinal strain (GLS)…2022 American Transplant Congress
De Novo Donor-Specific Antibody Development in Heart Transplant Recipients Following COVID-19 Vaccination
*Purpose: To determine the incidence of de novo donor-specific antibodies (DSAs) in recipients of orthotopic heart transplants (OHT) who received an mRNA vaccine against SARS-CoV-2.*Methods:…2022 American Transplant Congress
Left Ventricular Diastolic Dysfunction: Prevalence and Relation to Outcomes in Liver Transplantation Recipients
1University of Maryland, Baltimore, MD, 2University of Maryland School of Medicine, Baltimore, MD
*Purpose: Assess the prevalence and characteristics of patients with pre-transplant left ventricular diastolic dysfunction (LVDD) and its potential impact on post-transplant morbidity and mortality.*Methods: Retrospective…2022 American Transplant Congress
The Prevalence and Morbidity Associated with BK Virus in Heart Transplant Recipients
*Purpose: BK polyomavirus (BKV) is a quiescent polyomavirus that is present in approximately 80% of the population and can reactivate in immunocompromised patients and impair…2022 American Transplant Congress
Pericardial Effusion: A Potential Late Complication of COVID-19 Infection
Internal Medicine, Division of Nephrology, University of Texas Medical Branch, Galveston, TX
*Purpose: COVID-19 infection involves entry of SARS-CoV-2 virus into cells via interaction between its spike protein and angiotensin converting enzyme resulting in an NF-κβ mediated…
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