2016 American Transplant Congress
Clinical Significance of C3d Binding Donor Specific Anti-HLA Antibodies (DSA) Detected by Single Antigen Beads (SAB) After Kidney Transplantation.
A new Luminex-based SAB method detects DSA compliment fixing via C3d-binding. This study compares the clinical outcomes in kidney recipients that developed de novo DSA…2016 American Transplant Congress
The Combined Effect of Acute Rejection and De Novo Donor-Specific Antibodies on Kidney Allograft Survival.
Division of Renal Diseases and Hypertension, University of Colorado, Aurora, CO.
While dnDSA is associated with graft loss in multiple studies, the clinical context in which dnDSA develops and contributes to graft loss is less well…2016 American Transplant Congress
Post-Transplantation Hypomagnesemia as a Predictor of Survival Among the Kidney Transplant Population.
Transplant Research Center, Brigham and women's hospital, Boston, MA.
We have previously shown a robust relationship between low magnesium in the first year post-transplant and better long-term kidney allograft function. Given this somewhat counterintuitive…2016 American Transplant Congress
NAD+ Promotes Allograft Survival Independently of CD4+CD25+Foxp3+ Regulatory T Cells.
CD4+CD25+Foxp3+ regulatory T cells (Tregs) play a central role in the maintenance of immune tolerance and T cell homeostasis. It is known that Tregs promote…2016 American Transplant Congress
Composite Score to Define the Risk of Allograft Loss After Standard-of-Care Treatment of Antibody-Mediated Rejection in Kidney Transplantation.
The development of a reliable surrogate endpoint for allograft survival after AMR treatment is a current unmet need in clinical transplantation (FDA AMR Workshop). We…2016 American Transplant Congress
Detection of Venous Thrombi by Microdialysis Catheters and Angiographic Guided Thrombus Extraction in Two Solitary Pancreas Transplants.
Introduction: The complication rate after pancreas transplantation (PTx) is very high, with venous thrombosis being the most commonly occurring complication that leads to early graft…2016 American Transplant Congress
Endoscopic Polydimethylsiloxane Injection in Prevention of Recurrent Graft Pyelonephritis for Transplanted Kidney with Vesicoureteral Reflux.
Reccurent acute graft pyelonephritis (AGPN) with vesicoureteral reflux (GVUR) can have a deleterious impact on graft outcome. The objective of this study was to evaluate…2016 American Transplant Congress
Profiling of T Cell Subsets in a Primate Cardiac Transplant Model.
Surgery, University of Maryland, Baltimore, MD.
Purpose: Costimulation blockade prolongs graft survival but does not induce tolerance in primates, and mechanisms of rejection are incompletely understood. Here we evaluate changes in…2016 American Transplant Congress
Impact of Donor AKI on Outcome Following High KDPI Deceased Donor Kidney Transplantation.
Background: Transplanting deceased donor kidneys with AKI does not appear to have negative impact on graft survival, however the impact of AKI on high KDPI…2016 American Transplant Congress
Kidney Graft Homing of De Novo Donor Specific HLA Antibodies Is an Early Step within the Antibody-Mediated Graft Damage Process.
In this study, by a parallel analysis on sera and graft biopsies we have analyzed, in a pediatric cohort of unsensitized recipients of a first…
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