Articles tagged "Graft survival"

2019 American Transplant Congress
Excellent Outcomes in Liver Transplantation under Charity Care: An Opportunity to Mitigate Socio-Economic Disparities in Access to Transplantation
F. Paterno¹, J. Rosado¹, R. Olivo², S. Gavzy¹, L. Brown¹, D. Wilson¹, B. Koneru¹, N. Pyrsopoulos², J. V. Guarrera¹
¹Department of Surgery, Division of Transplant and Hepatobiliary Surgery, Rutgers New Jersey Medical School, Newark, NJ, ²Department of Medicine, Division of Hepatology, Rutgers New Jersey Medical School, Newark, NJ
*Purpose: Lack of health insurance is a major barrier in the access to health care even in the case of life-threatening conditions like end-stage liver…
2019 American Transplant Congress
Prevention of Islet Allo- and Xenograft Rejection with Immunoglobulin M Immunotherapy
M. Ma, P. Chhabra, K. Brayman
Surgery, University of Virginia, Charlottesville, VA
*Purpose: To investigate if IgM therapy mitigates islet allo- and xenotransplant rejection and promotes permanent islet survival.*Methods: 1) New onset diabetic NOD mice (n=14) were…
2019 American Transplant Congress
Room for Optimism; Improvement in Long-Term Patient and Graft Survival of Kidney Transplants in the United States over the past Three Decades
C. Wu, A. Rana, N. Galvan, C. O'Mahony, J. Goss, B. Murthy
Division of Abdominal Transplantation, Baylor College of Medicine, Houston, TX
*Purpose: Previous studies indicated that the short-term (1 year) allograft survival of kidney transplants has improved significantly over the years. However, less is known about…
2019 American Transplant Congress
B Cell-Specific IRE1a Deficiency Protects Renal Allografts from Rejection via Inhibition of Donor-Specific Antibodies and Induction of B Regulatory Cells
L. Qiu¹, J. Wang¹, X. Yeap¹, D. Fang², Z. J. Zhang¹
¹Comprehensive Transplant Center, Department of Surgery, Northwestern University, Chicago, IL, ²Department of Pathology, Northwestern University, Chicago, IL
*Purpose: Despite the progress in immunosuppressive regimens, antibody-mediated rejection remains a major contributor to renal allograft loss in recipients with donor-specific antibodies (DSA). IRE1a, an…
2019 American Transplant Congress
High Fibre Diet Prevents Transplant-Associated Dysbiosis and Prevents Kidney Allograft Rejection
J. J. Singer¹, H. Wu¹, T. Kwan¹, Y. Loh¹, C. Wang¹, J. Tan², L. Macia², S. Alexander³, S. Chadban¹
¹Kidney Node Laboratory, Charles Perkins Centre, The University of Sydney, Sydney, Australia, ²Nutritional Immunometabolism Lab, Charles Perkins Centre, The University of Sydney, Sydney, Australia, ³The Children's Hospital Westmead, Sydney, Australia
*Purpose: To investigate the impact of high fibre (HF) diet or dietary supplementation with the short chain fatty acid (SCFA) sodium acetate (SA) on kidney…
2019 American Transplant Congress
Aorto-Iliac Calcification is a Risk Factor for Inferior Patient and Graft Survival in Kidney Transplant Recipients; A Systematic Review and Meta-Analysis
A. A. Rijkse, J. L. van Dam, H. J. Kimenai, J. N. IJzermans, R. C. Minnee
HPB/Transplant surgery, Erasmus Medical Center, Rotterdam, Netherlands
*Purpose: While the incidence of transplanting a kidney onto atherosclerotic iliac arteries is becoming more common, little is known about the clinical outcome. We performed…
2019 American Transplant Congress
Outcomes of ABO Incompatible Transplant on Steroid Free Immunosuppression
A. Wang, D. Mishler, T. Taber, M. Yaqub, A. Sharfuddin, W. Goggins, O. Adebiyi
Department of Medicine, Division of Nephrology, Indiana University School of Medicine, Indianapolis, IN
*Purpose: ABO incompatible (ABOi) kidney transplant (KTx) was introduced to expand donor organ pool. However it is also an immunologically high-risk procedure requiring pre-transplant antibody…
2019 American Transplant Congress
Donor, Recipient Indices and Frailty Predict Outcomes after Heart-Kidney Transplantation
C. Beifeld¹, V. Dio Guardi¹, K. Lau¹, A. Di Carlo¹, S. Karhadkar²
¹Surgery, Temple University Hospital, Philadelphia, PA, ²Temple University Hospital, Philadelphia, PA
*Purpose: Simultaneous heart kidney transplantation (SHKT) is increasing in frequency; however there is a lack of consensus regarding patient selection criteria for this life saving…
2019 American Transplant Congress
Long-Term Outcomes and Safety of Living Kidney Transplantation from Older Donors
Y. Kakuta¹, M. Okumi¹, T. Kanzawa¹, K. Unagami², H. Ishida², K. Tanabe¹
¹Urology, Tokyo Women's Medical University, Tokyo, Japan, ²Organ Transplant Medicine, Tokyo Women's Medical University, Tokyo, Japan
*Purpose: The shortage of deceased donors and increase in the aging population have led to increased kidney transplantation using older living donors (LDs) in Japan,…
2019 American Transplant Congress
Lymphotoxin Beta Receptor Determines Lymph Node Structure for Treg Migration and Suppression of Graft Rejection
V. Saxena, W. Piao, L. Li, C. M. Paluskievicz, Y. Xiong, T. Simon, J. S. Bromberg
U Maryland, Baltimore, MD
*Purpose: Lymphotoxin beta receptor (LTβR) mediated signaling in lymphatic endothelium cells (LEC) is important for migration of regulatory T cells (Treg) to afferent lymphatic vessels…