Articles tagged "Graft survival"

2022 American Transplant Congress
COVID-19 Infection Post-Transplant: What is the Collateral Damage to the Graft? A Case for Pre-Transplant Vaccination
A. Fabick¹, E. Overly¹, V. Rao², V. Rohan³, N. Patel¹, D. DuBay³, C. Candland³, N. Pilch¹
¹Department of Pharmacy, Medical University of South Carolina, Charleston, SC, ²Department of Transplant Nephrology, Medical University of South Carolina, Charleston, SC, ³Department of Transplant Surgery, Medical University of South Carolina, Charleston, SC
*Purpose: COVID-19 produces an unpredictable immune reaction and is challenging to manage during active infection and post-infection, in kidney transplant (KTX) recipients. The first peak…
2022 American Transplant Congress
Long Term Analysis of Pediatric En-Bloc Kidney Transplantation: A Single Center Experience
H. H. Patel¹, P. Di Cocco², J. Almario², A. Fratti², S. Akshelyan², E. Benedetti², I. Tzvetanov², M. Spaggiari²
¹University of Missouri-Kansas City School of Medicine, Kansas City, MO, ²University of Illinois at Chicago, Chicago, IL
*Purpose: Pediatric en-bloc kidney transplantations for adult recipients are uncommonly performed due to unique donor characteristics, the technical challenge of the operation, and potential surgical…
2022 American Transplant Congress
Outcome of Living Donor Kidney Transplant and Deceased Donor Kidney Transplant: A Retrospective Cohort Study at National Kidney and Transplant Institute
A. B. Burog, A. Parayno
ORGAN TRANSPLANTATION AND VASCULAR SURGERY, National Kidney And Transplant Institute, Quezon City, Philippines
*Purpose: To compare the graft and patient survival of living and deceased donor kidney transplant and identify the factors that affect graft survival.*Methods: Retrospective cohort…
2022 American Transplant Congress
Binding Mechanisms For Donor Dc-derived Exosomes To Cross-dress Of Recipient Dc
L. ZHANG¹, X. LI¹, J. LIU¹, H. WEI¹, C. LI¹, A. HUANG², C. ZHENG¹, Q. LIU¹
¹Department of Biochemistry, Southern University of Science and Technology, Shenzhen, China, ²Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
*Purpose: Our previous evidence suggests donor dendritic cell (DC)-derived exosomes cross-dress recipient DC after heart transplantation in mice. This process plays a critical role in…
2022 American Transplant Congress
Risk Factors Associated with Medium-Term Allograft and Recipient Survival: Learned from 1,587 Adults with Single Kidney Transplantation
S. Chang¹, B. Liu¹, D. Du¹, N. Gong², L. Zhu¹, G. Chen¹, W. Zhang¹, Z. Chen²
¹Institute of Organ Transplantation,Tongji Hospital,Tongji Medical College,HUST, Wuhan, China, ²Huazhong University of Science and Technology, Wuhan, China
*Purpose: Retrospectively investigated the reason for graft failure during the perioperative period and discussed whether DGF and the high SCr level in a short time…
2022 American Transplant Congress
Long-Term Outcomes After Conversion to a Belatacept-Based Immunosuppression in Kidney Transplant: A Matched Cohort Study
G. Divard, C. Debiais, C. Legendre, O. Aubert, C. Lefaucheur, A. Loupy
Paris Transplant Group, INSERM, Paris, France
*Purpose: Conversion to belatacept after transplant seems to be safe. However, no studies have reported the long-term efficacy and safety outcomes after conversion to belatacept…
2022 American Transplant Congress
Overexpression of Human Ectonucleoside Triphosphate Diphosphohydrolase 1 (entpd1; Hcd39) Did Not Afford Significant Protection on Porcine Endothelial Cells
R. Matheson¹, B. Gonzalez Nolasco¹, K. Deng¹, R. Garofalo¹, N. Serifis¹, T. M. Coe¹, C. Rhatigan¹, D. Gil¹, D. Cloonan¹, K. Lee¹, K. Hall², M. Youd², J. F. Markmann¹, S. C. Robson³
¹Transplantation surgery research, Massachusetts General Hospital, Boston, MA, ²eGenesis Bio, Cambridge, MA, ³Beth Israel Deaconess Medical Center, Boston, MA
*Purpose: The thromboregulatory and anti-inflammatory potential of human CD39 (hCD39) makes it a gene of interest in xenotransplantation. In porcine endothelium, CD39 activity is generally…
2022 American Transplant Congress
PACAP-Mediated Autophagy Prevents Liver Ischemia Reperfusion Injury in OLT
Z. Xue, B. Yang, R. Busuttil, J. Kupiec-Weglinski, H. Ji
UCLA Medical Center, Los Angeles, CA
*Purpose: Pituitary adenylate cyclase-activating polypeptide (PACAP) is from vasoactive intestinal peptide-glucagon-secretin family. Our group was the first to demonstrate that neuropeptide PACAP, which innervates the…
2022 American Transplant Congress
High KDPI Kidneys: Lifelong Freedom from Dialysis for Elderly Patients
M. M. Romine¹, W. Irish², H. Jones³, A. Aaron², D. Leeser⁴
¹Department of Surgery, Eastern Carolina University, Greenville, NC, ²Eastern Carolina University, Greenville, NC, ³Eastern Nephrology Associates, Greenville, NC, ⁴East Carolina University, Greenville, NC
*Purpose: According to national data, there is an increase in kidney transplants in patients over 65, corresponding to an overall general increase. Elderly patients continue…
2022 American Transplant Congress
PSGL-1-mTOR-TIM3 Signaling in a Murine Model of Hindlimb Transplantation
K. Kadono¹, F. Messner², J. He², Y. Guo², B. Oh², G. Brandacher², J. Kupiec-Weglinski¹
¹UCLA Medical Center, Los Angeles, CA, ²Johns Hopkins UJohns Hopkins University School of Medicine, Baltimore, MD
*Purpose: Peri-transplant tissue damage driven by innate-adaptive immune cascades resulting from ischemia-reperfusion injury (IRI) is a major concern in vascularized composite allotransplantation (VCA). Here, we…

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