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American Transplant Congress abstracts

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Articles tagged "Graft failure"

  • 2015 American Transplant Congress

    Allograft Enterectomy as a Life-Saving Procedure and Salvage for Retransplantation

    S. Nagai, R. Mangus, B. Ekser, C. Kubal, J. Fridell, A. Tector.

    Transplant Surgery, Indiana University School of Medicine, Indianapolis, IN.

    Background: Allgraftectomy after solid organ transplantation is usually performed as a palliative therapy. After isolated intestinal transplantation (IIT), allograft enterectomy is sometimes necessary as a…
  • 2015 American Transplant Congress

    A Joint Survival Longitudinal Approach to Better Assess the Etiological Role of Risk Factors of Kidney Transplant Graft Failure

    M.-C. Fournier,1,2 E. Dantan,1 Y. Foucher,1,2 M. Giral.2

    1EA 4275 - SPHERE - Biostatistique, Pharmacoépidémiologie et Mesures Subjectives en Santé, Université de Nantes, Nantes, France; 2INSERM CR1064 Centre pour la Recherche en Transplantation et Immunointervention (CRTI), Institut Transplantation-Urologie-Néphrologie (ITUN), Nantes, France.

    Background. Although risk factors of graft failure after renal transplantation have been widely considered, it is difficult to distinguish their etiological role: a direct association…
  • 2015 American Transplant Congress

    Preformed IgA Antibodies to B2-Glycoprotein Is an Indepedent Risk Factor for Graft Thrombosis and Early Graft Loss After Renal Transplantation

    J. Morales,1 M. Serrano,3 J. Martinez,2 D. Perez,2 M. Sevilla,2 A. Amdres,3 E. Gonzalez,3 E. Paz-Artal,2 A. Serrano.2

    1Research Institute, hospital 12 de Octubre, Madrid, Spain; 2Immunology, Hospital 12 de Octubre, Madrid, Spain; 3Nephrology, Hospital 12 de Octubre, Madrid, Spain.

    Vessel trombosis represent the first cause of early graft loss (EGL)alter renal transplantation (RT). Our group recently described that preformed IgA antibodies to B2-Glycoprotein (…
  • 2015 American Transplant Congress

    Clinical Relevance of C3d-Binding Donor-Specific Antibodies in Late Kidney Allograft Failure

    J. Lan, D. Gjertson, Y. Zheng, DeKAF Investigators, E. Reed, M. Cecka.

    Path, UCLA, LA, CA.

    Background: The objective of this study was to investigate the prognostic value of C3d-binding donor-specific antibodies (DSA) in determining late kidney allograft failure.Methods: 1048 patients…
  • 2015 American Transplant Congress

    DSA Monitoring in Kidney Transplant Recipients

    F. Pean,1 M. Cooper,1 J. Verbesey,1 A. Gilbert,1 B. Javaid,1 R. Mohammed,1 O. Timofeeva,2 J. Moore,1 K. Cruz,1 R. Ghasemian,1 T. Fishbein,1 M. Grafals.1

    1Medstar Georgetown Transplant Institute, Georgetown University, Washington, DC; 2Clinical Laboratory and Histocompatibility, Georgetown University, Washington, DC.

    Introduction: The development of DSA monitoring is a new technique to detect antibodies in kidney transplant recipients. Data has shown that development of DSA post…
  • 2015 American Transplant Congress

    Live Donor Kidney Transplantation: Recipient Outcomes When the Donor Developed ESRD

    A. Muzaale, A. Massie, D. Segev.

    Johns Hopkins University, Baltimore, MD.

    Recipient outcomes when the donor developed ESRD remain uncharacterized.Method: A cohort of 99 LDKT recipients between 04/1994-11/2011, whose donors subsequently developed ESRD, was compared with…
  • 2015 American Transplant Congress

    Calcineurin-Inhibitor Conversion to mTOR Inhibitor in Renal Transplant Recipients Leads to Worse Long Term Clinical Outcomes

    A. Alvarado,1 A. Shetty,1 O. Traitanon,1 J. Leventhal,1 V. Mas,2 D. Chhabra,3 J. Matthews,1 L. Gallon.1

    1Comprehensive Transplant Center, Northwestern University, Chicago, IL; 2University of Virgina, Charlottesville, Va; 3Advocate Christ Medical Center, Chicago, IL.

    We previously reported the short-term feasibility of Calcineurin-Inhibitor (CNI) elimination in kidney transplant recipients. We now report the long-term clinical impact on renal allograft function…
  • 2015 American Transplant Congress

    Successful Management of Post Transplant Focal Segmental Glomerulosclerosis With Plasma Exchange and Rituximab

    K. Koutroutsos,1 R. Charif,1 C. Roufosse,2 J. Galliford,1 D. Taube,1 M. Loucaidou.1

    1Kidney and Transplant Centre, Imperial Healthcare NHS Trust, London, United Kingdom; 2Department of Histopathology, Imperial Healthcare NHS Trust, London, United Kingdom.

    Background: Post-transplant Focal Segmental Glomerulosclerosis (FSGS) is associated with renal allograft loss. Currently, optimal treatment remains controversial. We propose a management protocol that includes treatment…
  • 2015 American Transplant Congress

    Age-Specific Graft Failure Rates in Pediatric Heart Transplant Recipients

    B. Foster,1 M. Dahhou,1 X. Zhang,1 V. Dharnidharka,2 V. Ng,3 J. Conway.4

    1Pediatrics, Research Institute of the McGill Univ. Health Centre, Montreal, QC, Canada; 2Pediatrics, Washington Univ., St. Louis, MO; 3Pediatrics, Hospital for Sick Children, Toronto, ON, Canada; 4Pediatrics, Stollery Children's Hospital, Edmonton, AB, Canada.

    Graft failure risk has been shown to peak during emerging adulthood (18-25 y) among kidney transplant recipients. The association between age and graft failure risk…
  • 2015 American Transplant Congress

    Outcomes After Right Kidney Living Donor Transplant Are Associated With Center Volume

    R. Reed, P. MacLennan, B. Shelton, D. Sonnier, M. Hanaway, J. Goodman, C. Young, M. Deierhoi, J. Locke.

    Surgery/Transplantation, University of Alabama at Birmingham, Birmingham, AL.

    Background: Right kidney living donor transplant (RKLDT) is a high-risk, low-volume procedure that is associated with increased risk for early graft failure. It is unclear…
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